Patents by Inventor Hiroo KIMURA

Hiroo KIMURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230390459
    Abstract: The present invention relates to an axon bundle obtained by a method of culturing a nerve cell aggregation having one spheroid and an axon bundle extending from the spheroid wherein the nerve cell aggregation consisting of a plurality of neurons having a cell body and an axon obtained by a method comprising the following step: supplying a culture medium to one first chamber, one second chamber and one channel having the length of at least 1 mm, the width of 100 to 150 ?m and the height of 100 to 200 ?m, which connecting said first chamber and second chamber, wherein said first chamber, second chamber, and channel are contained in one of the modules disposed in a culture plate, seeding the first chamber with a nerve cell derived from a stem cell or a spheroid of primary cultured nerve cells; and culturing said nerve cell, thereby growing an axon bundle from said spheroid and extending them into said channel, wherein the length of the axon bundle obtained is 1 mm or more, and the diameter of the axon bundles
    Type: Application
    Filed: October 28, 2021
    Publication date: December 7, 2023
    Applicants: KEIO UNIVERSITY, Jiksak Bioengineering Inc.
    Inventors: Shinsuke SHIBATA, Hiroo KIMURA, Takayuki NISHIJIMA, Tomoko SHINDO, Hideyuki OKANO, Jiro KAWADA, Sayaka TOITA