Patents by Inventor Hiroo Maeda

Hiroo Maeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyethylene glycol substituted phenyl glyoxals
    Patent number: 5093531
    Abstract: A polyethylene glycol derivative of the formula ##STR1## wherein R represents a lower alkyl and n represents an optional positive integer which renders the average molecular weight of the polyethylene glycol moiety about 1,000 to 12,000, a peptide modified by said polyethylene glycol derivative and a method for production thereof.The polyethylene glycol derivative (I) is capable of modifying the guanidino groups in peptides. The peptides modified by the polyethylene glycol derivative (I) are extremely stable, are considerably delayed in biological clearance (i.e. the durability is extended) and exhibit their physiological activities effectively over the long period.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: March 3, 1992
    Assignee: Sumitomo Pharmaceuticals Company, Limited
    Inventors: Akihiko Sano, Hiroo Maeda, Yoshiyuki Kai, Keiichi Ono