Abstract: A crane includes a boom and a hook suspended from the boom by a wire rope and transports a load in a state in which the load W is suspended from the hook, and further includes a sensor that detects the position of an obstacle, and a control device that generates a transport path CR by arranging a plurality of node points in an area containing a lifting-up point and a lifting-down point of the load and connecting the node points. The control device generates a new transport path after increasing a number of node points arranged around the obstacle when the sensor detects movement of the obstacle.

Abstract: A fixing device includes an endless belt, a rotatable pressing member, a pad member inside of the belt, and a sliding member held by the pad member and sliding on an inner circumferential surface of the belt in a nip. The rotatable pressing member nips and feeds a recording material in the nip in cooperation with the belt and fixes a toner image on the recording material by applying heat and pressure. The sliding member includes a base material layer on which a plurality of projections projecting toward the rotatable pressing member are formed on a side sliding with the belt and a sliding layer provided on an outer surface of the plurality of projections. A shape of a surface of the sliding layer is a curved surface and a radius of curvature R of the curved surface satisfies 300 ?m?R?850 ?m.

Abstract: An image forming apparatus includes a first rotatable member, a second rotatable member, an air nozzle, and a pipe. The pipe includes a portion provided in a range overlapping with the first rotatable member and making one reciprocation or more in a case that when a direction crossing a feeding direction of a recording material fed in a nip is a widthwise direction of the first rotatable member, the pipe is viewed in a direction perpendicular to the widthwise direction.

Abstract: An image forming apparatus includes a first rotatable member, a second rotatable member, an air nozzle, and a pipe. The pipe includes a portion extending along a widthwise direction of the first rotatable member perpendicular to a recording material feeding direction.

Abstract: An image forming apparatus includes a reception unit to receive a job, heating and pressing rotary members to form a nip portion, and a spraying member having a nozzle and a cylinder. The nozzle discharges air to the heating rotary member and a recording material. During a period after the reception unit receives the job and before a leading edge of a first sheet of the recording material reaches the nip portion, the spraying member performs a spraying operation of spraying air in an amount greater than or equal to a predetermined amount. The air that the spraying member sprays on the first sheet of the recording material during the job is higher in temperature than the air that the spraying member sprays during the period after the reception unit receives the job and before the leading edge of the first sheet of the recording material reaches the nip portion.

Abstract: A fixing device includes an endless belt, a rotatable pressing member, a pad member inside of the belt, and a sliding member held by the pad member and sliding on an inner circumferential surface of the belt in a nip. The rotatable pressing member nips and feeds a recording material in the nip in cooperation with the belt and fixes a toner image on the recording material by applying heat and pressure. The sliding member includes a base material layer on which a plurality of projections projecting toward the rotatable pressing member are formed on a side sliding with the belt and a sliding layer provided on an outer surface of the plurality of projections. A leading end of the plurality of projections is a plane and an average roughness (Ra) of the plane satisfies 0.13 ?m?Ra?1.67 ?m.

Abstract: Without an increase in the cost, a movable range is defined. A first joint mechanism includes a base part, and a rotary part that rotates relatively to the base part. The first joint mechanism includes a regulated part that rotates together with the rotary part, a regulating part that is disposed on the extension of the rotation locus of the regulated part, and that has a function of regulating rotation of the regulated part relative to the base part, within a first movable range, and a movable range defining member that is disposed on either the base part or the rotary part, and that defines, as a movable range of the regulated part, a second movable range that is narrower than the first movable range.

Abstract: The present invention relates to a method for identifying cells having a predisposition to develop an intestinal phenotype, wherein the cells are characterized by the loss of expression of the RUNX3 gene and the expression of one or more intestinal marker genes. In particular, the invention is directed to the identification of cells, which exhibit an intestinal phenotype representing a precursor of gastric cancer. Furthermore, the invention discloses a method for identifying a compound inhibiting the development of an intestinal phenotype in cells having a predisposition to develop an intestinal phenotype. Finally, the invention also relates to kits of parts for performing these methods.

Abstract: The present invention relates to a method for identifying cells having a predisposition to develop an intestinal phenotype, wherein the cells are characterized by the loss of expression of the RUNX3 gene and the expression of one or more intestinal marker genes. In particular, the invention is directed to the identification of cells, which exhibit an intestinal phenotype representing a precursor of gastric cancer. Furthermore, the invention discloses a method for identifying a compound inhibiting the development of an intestinal phenotype in cells having a predisposition to develop an intestinal phenotype. Finally, the invention also relates to kits of parts for performing these methods.

Abstract: The present invention relates to a method for identifying cells having a predisposition to develop an intestinal phenotype, wherein the cells are characterized by the loss of expression of the RUNX3 gene and the expression of one or more intestinal marker genes. In particular, the invention is directed to the identification of cells, which exhibit an intestinal phenotype representing a precursor of gastric cancer. Furthermore, the invention discloses a method for identifying a compound inhibiting the development of an intestinal phenotype in cells having a predisposition to develop an intestinal phenotype. Finally, the invention also relates to kits of parts for performing these methods.