Patents by Inventor Hiroshi Hama
Hiroshi Hama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240142352Abstract: A clearing reagent in accordance with an embodiment of the present invention for making a biological material transparent is a solution containing: at least one compound selected from the group consisting of urea and a urea derivative; sorbitol; and a surfactant which is contained at a concentration of 5 (w/v) % or less.Type: ApplicationFiled: November 7, 2023Publication date: May 2, 2024Inventors: Atsushi MIYAWAKI, Hiroshi HAMA
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Publication number: 20230181426Abstract: A drug supply device includes: a plurality of cassettes configured to eject a drug one by one; and a control device configured to set a plurality of groups including a plurality of cassettes selected from among the plurality of cassettes. The control device selects a cassette that performs a drug ejection operation from each of the plurality of groups such that a number of tablets of a drug to be ejected from the plurality of cassettes that perform the drug ejection operation is each levelled in one of the plurality of group and among the plurality of groups.Type: ApplicationFiled: February 10, 2023Publication date: June 15, 2023Inventors: Akira KONDO, Hiroshi HAMA
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Publication number: 20210131925Abstract: A method for making a biological material transparent according to the present invention includes: a first permeation step of causing a first solution to permeate into a biological material, the first solution containing at least one compound selected from the group consisting of urea and urea derivatives at a predetermined concentration; and then a second permeation step of causing a second solution to permeate into the biological material, the second solution containing at least one compound selected from the group consisting of urea and urea derivatives at a concentration higher than the concentration of the at least one compound contained in the first solution.Type: ApplicationFiled: December 21, 2020Publication date: May 6, 2021Inventors: Atsushi Miyawaki, Hiroshi Hama, Hiroshi Kurokawa
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Publication number: 20210131926Abstract: A clearing reagent according to this invention for making a biological material transparent is a solution containing, as an active component, at least one compound selected from the group consisting of urea and urea derivatives, in order to provide a novel clearing reagent for making a biological material transparent.Type: ApplicationFiled: December 21, 2020Publication date: May 6, 2021Inventors: Atsushi Miyawaki, Hiroshi Hama, Hiroshi Kurokawa, Hiroyuki Kawano, Asako Sakaue
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Patent number: 10444124Abstract: A clearing reagent according to the present invention for making a biological material transparent is a solution containing: at a concentration of 1M or more and not more than 8.5M, at least one compound selected from the group consisting of urea and urea derivatives; and glycerol at a concentration of 25 (w/v) % or more and not more than 35 (w/v) %.Type: GrantFiled: May 18, 2012Date of Patent: October 15, 2019Assignee: RIKENInventors: Atsushi Miyawaki, Hiroshi Hama, Asako Sakaue
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Patent number: 10254276Abstract: An antibody composition, which is an aspect of the present invention, contains at least one compound selected from the group consisting of urea and urea derivatives, the compound being contained in the antibody composition at a concentration of not less than 0.1 M and less than 1 M, the antibody composition being a solution.Type: GrantFiled: July 10, 2013Date of Patent: April 9, 2019Assignee: RIKENInventors: Atsushi Miyawaki, Hiroshi Hama
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Patent number: 9889957Abstract: A drug packaging device is provided in which both sheets are easily connectable to each other with a simple construction. A working plate having a first portion for temporarily fixing an end portion of a sheet remaining at a drug filling unit side, and a second portion for temporarily fixing an end portion of a new sheet are provided. The end portions of the respective packaging sheets which are temporarily fixed at the first portion and the second portion are connectable to each other.Type: GrantFiled: December 27, 2013Date of Patent: February 13, 2018Assignee: PANASONIC HEALTHCARE HOLDINGS CO., LTD.Inventors: Akinori Hatsuno, Hiroshi Hama
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Publication number: 20170370810Abstract: A clearing reagent in accordance with an embodiment of the present invention for making a biological material transparent is a solution containing: at least one compound selected from the group consisting of urea and a urea derivative; sorbitol; and a surfactant which is contained at a concentration of 5 (w/v) % or less.Type: ApplicationFiled: January 20, 2016Publication date: December 28, 2017Inventors: Atsushi MIYAWAKI, Hiroshi HAMA
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Publication number: 20150346196Abstract: An antibody composition, which is an aspect of the present invention, contains at least one compound selected from the group consisting of urea and urea derivatives, the compound being contained in the antibody composition at a concentration of not less than 0.1 M and less than 1 M, the antibody composition being a solution.Type: ApplicationFiled: July 10, 2013Publication date: December 3, 2015Inventors: Atsushi Miyawaki, Hiroshi Hama
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Publication number: 20140178927Abstract: A clearing reagent according to the present invention for making a biological material transparent is a solution containing: at a concentration of 1M or more and not more than 8.5M, at least one compound selected from the group consisting of urea and urea derivatives; and glycerol at a concentration of 25 (w/v) % or more and not more than 35 (w/v) %.Type: ApplicationFiled: May 18, 2012Publication date: June 26, 2014Applicant: RIKENInventors: Atsushi Miyawaki, Hiroshi Hama, Asako Sakaue
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Publication number: 20140109514Abstract: A drug packaging device is provided in which both sheets are easily connectable to each other with a simple construction. A working plate having a first portion for temporarily fixing an end portion of a sheet remaining at a drug filling unit side, and a second portion for temporarily fixing an end portion of a new sheet are provided. The end portions of the respective packaging sheets which are temporarily fixed at the first portion and the second portion are connectable to each other.Type: ApplicationFiled: December 27, 2013Publication date: April 24, 2014Applicant: PANASONIC HEALTHCARE CO., LTD.Inventors: Akinori Hatsuno, Hiroshi Hama
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Publication number: 20140109528Abstract: A drug-packaging device is provided that can reduce the number of steps executed by a worker with suppressing waste of a sheet which is caused by sheet exchange. A detection sensor for detecting the connection site between a packaging sheet remaining at a drug filling unit side and a new package sheet is provided, and drug filling processing at the connection site is skipped.Type: ApplicationFiled: December 27, 2013Publication date: April 24, 2014Applicant: PANASONIC HEALTHCARE CO., LTD.Inventors: Hiroshi Hama, Akinori Hatsuno
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Publication number: 20140087419Abstract: A method for making a biological material transparent according to the present invention includes: a first permeation step of causing a first solution to permeate into a biological material, the first solution containing at least one compound selected from the group consisting of urea and urea derivatives at a predetermined concentration; and then a second permeation step of causing a second solution to permeate into the biological material, the second solution containing at least one compound selected from the group consisting of urea and urea derivatives at a concentration higher than the concentration of the at least one compound contained in the first solution.Type: ApplicationFiled: April 27, 2012Publication date: March 27, 2014Applicant: RIKENInventors: Atsushi Miyawaki, Hiroshi Hama, Hiroshi Kurokawa
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Patent number: 8420781Abstract: An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived from Fungia sp., and a novel chromoprotein and fluorescent protein derived from Montipora. sp.Type: GrantFiled: August 2, 2011Date of Patent: April 16, 2013Assignees: Riken, Medical & Biological Laboratories Co., Ltd.Inventors: Atsushi Miyawaki, Takako Kogure, Hiroshi Hama, Masataka Kinjo, Kenta Saito, Satoshi Karasawa, Toshio Araki
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Publication number: 20130045503Abstract: A clearing reagent according to this invention for making a biological material transparent is a solution containing, as an active component, at least one compound selected from the group consisting of urea and urea derivatives, in order to provide a novel clearing reagent for making a biological material transparent.Type: ApplicationFiled: March 11, 2011Publication date: February 21, 2013Applicant: RIKENInventors: Atsushi Miyawaki, Hiroshi Hama, Hiroshi Kurokawa, Hiroyuki Kawano, Asako Sakaue
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Publication number: 20120034643Abstract: An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived from Fungia sp., and a novel chromoprotein and fluorescent protein derived from Montipora. sp.Type: ApplicationFiled: August 2, 2011Publication date: February 9, 2012Applicants: MEDICAL & BIOLOGICAL LABORATORIES CO., LTD., RIKENInventors: Atsushi MIYAWAKI, Takako KOGURE, Hiroshi HAMA, Masataka KINJO, Kenta SAITO, Satoshi KARASAWA, Toshio ARAKI
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Patent number: 8017746Abstract: An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived from Fungia sp., and a novel chromoprotein and fluorescent protein derived from Montipora. sp.Type: GrantFiled: December 3, 2004Date of Patent: September 13, 2011Assignees: Riken, Medical & Biological Laboratories Co., Ltd.Inventors: Atsushi Miyawaki, Takako Kogure, Hiroshi Hama, Masataka Kinjo, Kenta Saito, Satoshi Karasawa, Toshio Araki
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Publication number: 20070292909Abstract: An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived from Fungia sp., and a novel chromoprotein and fluorescent protein derived from Montipora. sp.Type: ApplicationFiled: December 3, 2004Publication date: December 20, 2007Inventors: Atsushi Miyawaki, Takako Kogure, Hiroshi Hama, Masataka Kinjo, Kenta Saito, Satoshi Karasawa, Toshio Araki
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Publication number: 20070080319Abstract: A corrosion inhibitor for magnesium and/or magnesium alloy containing, as an effective component, a least one kind of compound selected from the group consisting of a compound of the formula (1) and a compound of the formula (2) and salts thereof, and a process for producing components or parts made of magnesium and/or magnesium alloy using the corrosion inhibitor wherein R1 is a hydrogen atom, or C1-4 alkyl, R2 is a hydrogen atom, C1-4 alkyl, mercapto or hydroxy, R3 is a hydrogen atom, C1-4 alkyl or hydroxy, A is —N? or —C(R4)?, R4 is a hydrogen atom or amino.Type: ApplicationFiled: November 10, 2003Publication date: April 12, 2007Inventors: Kazunori Fukumura, Yuhua Yu, Masaya Kajimoto, Hiroshi Hama, Takashi Hamauzu, Hiroshi Yagi
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Patent number: 7155659Abstract: A signal separation circuit (11) normally outputs a main signal, but outputs a TMCC signal when an error detection and correction unit (4) sets a completion flag. Main signals are input via a selection circuit (3) to an execution unit (4), where error correction of the main signals is performed. The error-corrected main signals are supplied via a switching circuit (8) to a first data output circuit (9). Meanwhile, TMCC signals are input via the selection circuit (3) to an execution unit (4), error correction is carried out to the TMCC signals. The error-corrected TMCC signals are supplied via switching circuit (8) to a second data output circuit (10).Type: GrantFiled: March 23, 2001Date of Patent: December 26, 2006Assignee: Sanyo Electric Co., Ltd.Inventor: Hiroshi Hama