Abstract: A solid-state imaging device includes: a plurality of pixel circuits arranged in rows and columns; a plurality of selector circuits that each receive, as inputs, two pixel signals corresponding to two columns different from each other; k column AD conversion circuits that perform AD conversion on pixel signals output from the plurality of selector circuits, k being an integer greater than or equal to two; and m column AD conversion circuits that are provided redundantly. In the solid-state imaging device, the plurality of selector circuits selectively exclude, from among the k column AD conversion circuits and the m column AD conversion circuits, m column AD conversion circuits corresponding to m columns adjacent to each other, and associate k pixel signals output from the plurality of pixel circuits with k column AD conversion circuits which have not been excluded.

Abstract: A composite molded article is manufactured in such a manner that a molding mold that forms a molding space by mold closing and has a weir portion projecting into the molding space is opened, a flat plate-like first member that is softened under heating is arranged in a part of a portion where the molding space is formed, the stereoscopic first molded portion is formed with mold closing, simultaneously an injected molten resin is filled in a remaining portion of the molding space around the first member outside the weir portion in a state that the weir portion is made to abut against a thin portion provided at a peripheral edge of the first molded portion, and the second molding portion joined to the first molding portion is formed by hardening molten resin after the resin is caused to contact the first molded portion.

Abstract: The object is to provide a novel therapeutic strategy achieving high therapeutic effect on a skeletal dysplasia caused by excessive activation of FGFR3, particularly achondroplasia and hypochondroplasia. Provided is a therapeutic agent for a skeletal dysplasia, including meclizine or its pharmaceutically acceptable salt as an active ingredient.