Patents by Inventor Hiroshi Kiyokawa

Hiroshi Kiyokawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7750156
    Abstract: The present invention provides an industrially advantageous method of producing aminophenol compounds represented by the formula (1) by a simple and easy procedure at a high yield and a high purity.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: July 6, 2010
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Kiyokawa, Shinji Aki
  • Publication number: 20070219374
    Abstract: The present invention provides an industrially advantageous method of producing aminophenol compounds represented by the formula (1) by a simple and easy procedure at a high yield and a high purity.
    Type: Application
    Filed: March 25, 2005
    Publication date: September 20, 2007
    Inventors: Hiroshi Kiyokawa, Shinji Aki
  • Patent number: 6037046
    Abstract: An electromagnetic wave absorption panel for use in building construction includes a protective tile layer, an absorber layer, a metal reflective layer, and a building support layer, such as concrete. The absorber layer is multi-component structure, such as: a high dielectric constant layer and ferrite layer; a ferrite layer and a low dielectric constant layer; a ferrite and a polymer; a polymer and a material having a higher dielectric constant than the polymer; a ferroelectric, a ferrite, and a polymer; a ferrite, a polymer, and a high dielectric constant material; and a high dielectric constant material, a material in which the imaginary part of the permeability is greater than or equal to the real part of the permeability, and a low dielectric constant material. The invention also includes combinations of the above, such as: a high dielectric constant material, a ferrite, and a low dielectric constant material; and multiple layers of a ferrite and a polymer.
    Type: Grant
    Filed: January 13, 1997
    Date of Patent: March 14, 2000
    Assignees: Symetrix Corporation, Fujita Corporation
    Inventors: Vikram Joshi, Kenichi Kimura, Carlos A. Paz de Araujo, Hiroshi Kiyokawa
  • Patent number: 5853889
    Abstract: An electromagnetic wave absorption panel for use in building construction includes a protective tile layer, an absorber layer, a metal reflective layer, and a building support layer, such as concrete. The absorber layer utilizes novel materials including high dielectric constant materials, such as ABO.sub.3 type perovskites, layered superlattice materials, conducting oxides, and signet magnetics, ferroelectrics, such as ABO.sub.3 type perovskites and layered superlattice materials, garnets, a nickel-zinc ferrite, Ni.sub.0.4 Zn.sub.0.6 Fe.sub.2 O.sub.4, and polymer-ceramic composites of the above materials.
    Type: Grant
    Filed: January 13, 1997
    Date of Patent: December 29, 1998
    Assignees: Symetrix Corporation, Fujita Corporation
    Inventors: Vikram Joshi, Kenichi Kimura, Carlos A. Paz de Araujo, Hiroshi Kiyokawa
  • Patent number: 5516777
    Abstract: This invention provides a condensed pyrazole derivative of the Formula (1): ##STR1## (where A denotes CH or N, R.sup.0 and R.sup.3 denote same or different, a hydrogen atom or a lower alkyl group, R.sup.1 and R.sup.2 denote same or different, a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group or a halogen atom, m denotes 1 or 2, and n denotes 1, 2 or 3, provided that, when n is 2, two R.sup.2 may be connected to each other to form a lower alkylenedioxy group), or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of action of androgen, thereby being excellent in therapeutical effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long lasting of efficacy and high oral absorption.
    Type: Grant
    Filed: January 17, 1995
    Date of Patent: May 14, 1996
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Kiyokawa, Satoshi Yamada, Keisuke Miyajima, Koji Edamatsu, Kunihiko Tatsumi, Takeshi Yamauchi, Kazumasa Kishi, Kunihiko Kiyono
  • Patent number: 5420128
    Abstract: The invention discloses a pyrimidien derivative expressed in Formula [I]: ##STR1## where R.sup.1 denotes a hydrogen atom or hydroxyl group, R.sup.2 denotes a hydrogen atom, lower alkoxycarbonyl group, lower alkoxy group, halogen atom, lower alkyl group, cycloalkyl group with 3 to 8 carbon atoms, lower alkoxycarbonyl lower alkyl group, carboxyl group, carboxy lower alkyl group, group: --CONHR.sup.6 (R.sup.
    Type: Grant
    Filed: June 9, 1992
    Date of Patent: May 30, 1995
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Kiyokawa, Satoshi Yamada, Keisuke Miyajima, Kinji Hashimoto, Masatoshi Inai, Makoto Inoue, Kunihiko Tatsumi, Takeshi Yamauchi, Kazunobu Kurisu, Yoshifumi Chone
  • Patent number: 5409928
    Abstract: This invention provides a condensed pyrazole derivative of the Formula (1): ##STR1## (where A denotes CH or N, R.sup.0 and R.sup.3 denote same or different, a hydrogen atom or a lower alkyl group, R.sup.1 and R.sup.2 denote same or different, a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group or a halogen atom, m denotes 1 or 2, and n denotes 1, 2 or 3, provided that, when n is 2, two R.sup.2 may be connected to each other to form a lower alkylenedioxy group), or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of action of androgen, thereby being excellent in therapeutical effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long lasting of efficacy and high oral absorption.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: April 25, 1995
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Kiyokawa, Satoshi Yamada, Keisuke Miyajima, Koji Edamatsu, Kunihiko Tatsumi, Takeshi Yamauchi, Kazumasa Kishi, Kunihiko Kiyono
  • Patent number: 4824834
    Abstract: Pyrazolotriazine compounds of the formula: ##STR1## wherein R.sup.1 is OH or alkanoyloxy; R.sup.2 is H, OH, or SH; R.sup.3 is (1) unsaturated N- or S-containing heterocyclic group optionally having 1-2 substituents of halogen, nitro or phenylthio, (2) naphthyl, (3) phenyl optionally having 1-3 substituents of (i) alkyl, (ii) phenyl, (iii) alkoxycarbonyl, (iv) cyano, (v) nitro, (vi) alkoxy, (vii) phenylalkoxy (viii) phenylthio-alkyl, (ix) phenoxy, (x) ##STR2## R is alkyl, halo-substituted alkyl, phenyl optionally having 1-3 substituents, or pyridyl, and l is 0, 1 or 2, (xi) halogen, (xii) phenylalkyl, (xiii) carboxy, (xiv) alkanoyl, (xv) benzoyl optionally having 1-3 substituents, (xvi) amino, (xvii) OH, (xviii) alkanoyloxy, (xix) ##STR3## or (xx) ##STR4## (A is alkylene), said compounds having a xanthine oxidase inhibitory activity and are useful for the prophylaxis and treatment of gout.
    Type: Grant
    Filed: October 8, 1987
    Date of Patent: April 25, 1989
    Assignee: Otsuka Pharmaceutical Company, Limited
    Inventors: Setsuro Fujii, Hiroyuki Kawamura, Hiroshi Kiyokawa, Satoshi Yamada