Abstract: The purpose of the present invention is to provide a screening method that enables efficient discovery of a novel senolytic drug and a senolytic drug obtained by the screening method. The present invention pertains to a senolytic drug that inhibits binding between PGAM and Chk1 and also selectively kills senescent cells. More particularly, the senolytic drug of the present invention contains, as an active ingredient, at least one selected from the group consisting of an mRSK1 kinase inhibitor, an Fak kinase inhibitor, an inhibitor of signaling pathways involving Fak kinase, a CDK inhibitor, a calcium antagonist agent, an inotropic glycoside, a DNA damaging agent, an antimicrobial agent, an Aurora kinase inhibitor, a flavonoid, a PI3K kinase inhibitor, an HDAC inhibitor, a therapeutic agent for age-related macular degeneration, a p38 MAPK inhibitor, an mTOR inhibitor, a tyrosine kinase inhibitor, a Bcl-2 inhibitor, statin, a serotonin receptor antagonist, other kinase inhibitors and Nutlin-3b.

Abstract: A robot includes a movable unit and a driving unit that drives the movable unit. The movable unit includes a predicted colliding section that is a structure forming an outer shape of the movable unit and may collide with a human body during movement of the movable unit. The predicted colliding section is formed to have a predetermined shape such that a pressure applied to a human body is lower than a predetermined safety standard value for pressure for the human body when the movable unit is driven at maximum thrust by the driving unit and collides with the human body.

Abstract: A method for suppressing aging includes obtaining a blood sample from a subject, detecting one or more blood metabolites in the blood sample, identifying the subject as having a biological age greater than a chronological age of the subject by determining metabolite levels of the one or more blood metabolites of the subject, and subjecting the identified subject to fasting more than 10 hours.

Abstract: A wireless power supply apparatus includes a power reception coil, an actual load and an auxiliary load. The power reception coil functions as a repeater for receiving electric power in a non-contact manner by magnetic resonance with a power transmission coil to which electric power is supplied from a power supply unit and relaying transfer of the electric power from the power transmission coil. The actual load is connected to the power reception coil and is powered by the electric power received by the power reception coil. The auxiliary load is inserted parallel to the power reception coil and the actual load and forms a closed circuit with the power reception coil when supply of the electric power to the actual load is interrupted to be in an open state.

Abstract: A direct drive type system such as a direct drive type robot is provided. This system includes a rail member, a movable member guided by the rail member and movable along the rail member, and an electric motor to drive the movable member. The system includes a transmission coil and a reception coil. The transmission coil has plural transmission coil segments which are planar coils and arranged on and along the rail member. High-frequency power is supplied to the transmission coil from a power source. The reception coil is arranged on the movable member to be opposed to the transmission coil and configured to an area faced with each of the transmission coil segments, wherein the area is smaller than that of each transmission coil segment. The reception coil receives power from the transmission coil without contact by a magnetic resonance. The received power is supplied to the motor.

Abstract: A robot includes a movable unit and a driving unit that drives the movable unit. The movable unit includes a predicted colliding section that is a structure forming an outer shape of the movable unit and may collide with a human body during movement of the movable unit. The predicted colliding section is formed to have a predetermined shape such that a pressure applied to a human body is lower than a predetermined safety standard value for pressure for the human body when the movable unit is driven at maximum thrust by the driving unit and collides with the human body.

Abstract: A wireless power supply apparatus includes a power reception coil, an actual load and an auxiliary load. The power reception coil functions as a repeater for receiving electric power in a non-contact manner by magnetic resonance with a power transmission coil to which electric power is supplied from a power supply unit and relaying transfer of the electric power from the power transmission coil. The actual load is connected to the power reception coil and is powered by the electric power received by the power reception coil. The auxiliary load is inserted parallel to the power reception coil and the actual load and forms a closed circuit with the power reception coil when supply of the electric power to the actual load is interrupted to be in an open state.

Abstract: A direct drive type system such as a direct drive type robot is provided. This system includes a rail member, a movable member guided by the rail member and movable along the rail member, and an electric motor to drive the movable member. The system includes a transmission coil and a reception coil. The transmission coil has plural transmission coil segments which are planar coils and arranged on and along the rail member. High-frequency power is supplied to the transmission coil from a power source. The reception coil is arranged on the movable member to be opposed to the transmission coil and configured to an area faced with each of the transmission coil segments, wherein the area is smaller than that of each transmission coil segment. The reception coil receives power from the transmission coil without contact by a magnetic resonance. The received power is supplied to the motor.

Abstract: In a sensor and a radar for measuring the distance and the moving speed of a target by radiating a radio frequency, particularly a millimeter wave, compatibility between cost reduction and high detection performance has been conventionally a significant problem. In the present invention, the frequency of a transmitted signal changes during a fixed time while performing digitally-frequency-modulation on frequency sweeping straight lines extending, with different slopes relative to the time axis, from plural slightly different initial values serving as starting points, the signal is transmitted after being modulated so as to periodically repeat the sweep time serving as a unit, signal components corresponding to the respective sweeping slopes are digitally sampled, in synchronization with the transmitted modulation signal, from a received signal which is reflected and returned from a target, and the received signal is analyzed.

Abstract: There is provided a highly accurate velocity sensor having a reduced detection error. A sensor circuit unit generates an electromagnetic wave and emits it from a transmission antenna. Furthermore, a reception antenna receives a reflection wave from the ground and a mixer mixes it with a local signal, thereby generating a low-frequency signal. The electromagnetic wave emitted from the sensor circuit unit shapes a beam by a dielectric lens before emitting it toward the ground. Here, the beam shape is such that the beam width in the vicinity of the sensor is smaller than the beam width in the vicinity of the ground.

Abstract: When printing job notice information is received from an information processing apparatus and a printing job execution instruction is received from a user, an image forming apparatus generates printing job generation information based on whether the printing job execution instruction matches the printing job notice information. Based on the printing job generation information, the information processing apparatus determines whether to generate the printing job.

Abstract: There is provided a semiconductor device able to increase the mobility of carriers and reduce the current in the OFF state. The semiconductor device includes a gate electrode, an insulating layer on the gate electrode, a first electrode on the insulating layer, a second electrode on the insulating layer at an interval with the first electrode, an organic semiconductor layer disposed in the interval between the first electrode and the second electrode and covering at least part of the first electrode and the second electrode, and a first resistance layer formed on the organic semiconductor layer and having an electrical resistance lower than that of the organic semiconductor layer. The first resistance layer is formed from conductive polymers.

Abstract: An organic transistor is capable of emitting light at high luminescence efficiency, operating at high speed, handling large electric power, and can be manufactured at low cost. The organic transistor includes an organic semiconductor layer between a source electrode and a drain electrode, and gate electrodes shaped like a comb or a mesh, which are provided at intervals approximately in the central part of the organic semiconductor layer approximately parallel to the source electrode and the drain electrode. The organic semiconductor layer consists of an electric field luminescent organic semiconductor material such as compounds of naphthalene, anthracene, tetracene, pentacene, hexacene, a phthalocyanine system compound, an azo system compound, a perylene system compound, a triphenylmethane compound, a stilbene compound, poly N-vinyl carbazole, and poly vinyl pyrene.

Abstract: An automotive radar having a high level of azimuth accuracy and a broad detectable range by virtue of preventing leaks of unnecessary waves to receiving antennas is to be provided. A transmitting array antenna 1 and receiving array antennas 2a, 2b are arranged on an antenna plate (grounding conductor plate) 3 which serves to ground the antennas, and radio wave absorbers 4 are arranged on two sides of the edges 15 of the antenna plate 3. The radio wave absorbers 4 may be configured of, for instance, a sponge material containing radio wave absorbing grains.

Abstract: In a sensor and a radar for measuring the distance and the moving speed of a target by radiating a radio frequency, particularly a millimeter wave, compatibility between cost reduction and high detection performance has been conventionally a significant problem. In the present invention, the frequency of a transmitted signal changes during a fixed time while performing digitally-frequency-modulation on frequency sweeping straight lines extending, with different slopes relative to the time axis, from plural slightly different initial values serving as starting points, the signal is transmitted after being modulated so as to periodically repeat the sweep time serving as a unit, signal components corresponding to the respective sweeping slopes are digitally sampled, in synchronization with the transmitted modulation signal, from a received signal which is reflected and returned from a target, and the received signal is analyzed.

Abstract: There is provided a highly accurate velocity sensor having a reduced detection error. A sensor circuit unit generates an electromagnetic wave and emits it from a transmission antenna. Furthermore, a reception antenna receives a reflection wave from the ground and a mixer mixes it with a local signal, thereby generating a low-frequency signal. The electromagnetic wave emitted from the sensor circuit unit shapes a beam by a dielectric lens before emitting it toward the ground. Here, the beam shape is such that the beam width in the vicinity of the sensor is smaller than the beam width in the vicinity of the ground.

Abstract: There is provided a highly accurate velocity sensor having a reduced detection error. A sensor circuit unit generates an electromagnetic wave and emits it from a transmission antenna. Furthermore, a reception antenna receives a reflection wave from the ground and a mixer mixes it with a local signal, thereby generating a low-frequency signal. The electromagnetic wave emitted from the sensor circuit unit shapes a beam by a dielectric lens before emitting it toward the ground. Here, the beam shape is such that the beam width in the vicinity of the sensor is smaller than the beam width in the vicinity of the ground.

Abstract: A high frequency circuit module for use in an automotive radar or the like, in which RF circuit parts are mounted on both sides of a hard multilayer dielectric substrate, and a transmission line connecting the RF circuit parts provided on both sides is constructed by a via group including a periodical structure or a via having a coaxial structure perpendicular to faces of the multilayer dielectric substrate. As the multilayer dielectric substrate, a hard multilayer substrate using metallic layers as a microstrip line wiring layer, a DC/IF signal line layer, and grounding metal layers for shielding which are disposed on and under the DC/IF signal line is employed. By using the transmission line achieved by a through via having the periodical structure or the through via having the coaxial structure, an electromagnetic wave propagating in parallel between the grounding conductors is confined.

Abstract: The invention intends to provide a sensor module suitable for miniaturization and reduction in costs, in the radar sensor that uses a millimeter or sub-millimeter wave signal of which frequency is more than 20 GHz. To accomplish this problem, the radar sensor is integrated into a one chip MMIC, in which an active circuit including an oscillator and a mixer is formed with an antenna on one semiconductor substrate. Further, the MMIC is sealed with a resin package. A dielectric lens is formed on the resin package over the antenna to attain a desired beamwidth. Thereby, the lens and the resin package can integrally be formed by a metal mold, thus reducing the cost.

Abstract: There is provided a semiconductor device able to increase the mobility of carriers and reduce the current in the OFF state. The semiconductor device includes a gate electrode, an insulating layer on the gate electrode, a first electrode on the insulating layer, a second electrode on the insulating layer at an interval with the first electrode, an organic semiconductor layer disposed in the interval between the first electrode and the second electrode and covering at least part of the first electrode and the second electrode, and a first resistance layer formed on the organic semiconductor layer and having an electrical resistance lower than that of the organic semiconductor layer. The first resistance layer is formed from conductive polymers.