Patents by Inventor Hiroshi Kuga

Hiroshi Kuga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11954312
    Abstract: An input device includes a touch panel having an operation surface and configured to receive a touch input and a hover input by an operation body; a display device configured to display a plurality of selection items; a memory; and a processor coupled to the memory. The processor is configured to highlight a selection item, a selection of the selection item being made by the hover input from the plurality of selection items, confirm the selection of the selection item by the hover input in a case where a duration during which the selection item is selected by the hover input reaches a first predetermined threshold, and confirm a selection of the selection item by the touch input in a case where the touch input is detected on the selection item before the duration reaches the first predetermined threshold.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: April 9, 2024
    Assignee: ALPS ALPINE CO., LTD.
    Inventors: Toshiki Nakamura, Hiroshi Shigetaka, Hirofumi Kuga, Masahiro Takata, Yasuji Hagiwara
  • Publication number: 20210169852
    Abstract: A protein that recognizes a drug moiety of an antibody-drug conjugate in which a drug represented by the following formula is conjugated to an antibody via a linker, and a method for quantifying the concentration in plasma of an antibody-drug conjugate in a mammal to which the antibody-drug conjugate has been administered, by using the protein, and a method for identifying a tissue distribution of an antibody-drug conjugate.
    Type: Application
    Filed: July 26, 2019
    Publication date: June 10, 2021
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Masako SOMA, Hiroshi KUGA, Takeshi MASUDA, Junko KAWAMURA, Hiromi ISHIBASHI, Satoru YASUDA
  • Patent number: 7041818
    Abstract: A DDS compound comprising a carboxy(C1-4)alkyldextran polyalcohol modified with a saccharide compound and a residue of drug compound bound to the carboxy(C1-4)alkyldextran polyalcohol, and a method for measuring a DDS compound in which a polymer carrier and a residue of drug compound are bound to each other by means of a spacer comprising 2 to 8 amino acids linked by peptide bond(s), which comprises the steps of treating the DDS compound with a peptidase, and measuring the resulting hydrolysate.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: May 9, 2006
    Assignee: Daiichi Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Susaki, Kazuhiro Inoue, Hiroshi Kuga, Masahiro Ikeda, Yoshinobu Shiose
  • Patent number: 6838450
    Abstract: A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: January 4, 2005
    Assignees: Daiichi Pharmaceutical Co., LTD, Drug Delivery System Institute, Ltd.
    Inventors: Kazuhiro Inoue, Hiroshi Susaki, Masahiro Ikeda, Hiroshi Kuga, Eiji Kumazawa, Akiko Togo
  • Patent number: 6835807
    Abstract: A drug complex useful as a DDS compound, which is represented by the following formula: A-R—NH—Y—CH2—O—CO-Q, wherein A is a polymer as a drug carrier; R is a spacer, wherein the spacer is an amino acid or an oligopeptide comprising 2 to 8 amino acids; Y is phenylene group which may be substituted; and Q is a residue of a drug compound such as antineoplastic agents. The complex provides rapid and site-selective release of a drug compound such as antineoplastic or anti-inflammatory agents and surely exhibits expected efficacy.
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: December 28, 2004
    Assignee: Daiichi Pharmaceuticals Co., Ltd.
    Inventors: Hiroshi Susaki, Kazuhiro Inoue, Hiroshi Kuga
  • Patent number: 6811996
    Abstract: A drug delivery system compound comprising a carboxy(C1-4)alkyldextran polyalcohol modified with a saccharide compound and a residue of drug compound bound to the carboxy(C1-4)alkyldextran polyalcohol, and a method for measuring a drug delivery system compound in which a polymer carrier and a residue of drug compound are bound to each other by a spacer comprising 2 to 8 amino acids linked by peptide bond(s), which comprises treating the drug delivery system compound with a peptidase, and measuring the resulting hydrolysate.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: November 2, 2004
    Assignee: Daiichi Pharmaceutical Co., Ltd.
    Inventors: Kazuhiro Inoue, Hiroshi Kuga, Yoshinobu Shiose, Hiroshi Korenaga
  • Publication number: 20040192644
    Abstract: A DDS compound comprising a carboxy(C1-4)alkyldextran polyalcohol modified with a saccharide compound and a residue of drug compound bound to the carboxy(C1-4)alkyldextran polyalcohol, and a method for measuring a DDS compound in which a polymer carrier and a residue of drug compound are bound to each other by means of a spacer comprising 2 to 8 amino acids linked by peptide bond(s), which comprises the steps of treating the DDS compound with a peptidase, and measuring the resulting hydrolysate.
    Type: Application
    Filed: April 13, 2004
    Publication date: September 30, 2004
    Applicant: Daiichi Pharmaceutical Co., Ltd.
    Inventors: Hiroshi Susaki, Kazuhiro Inoue, Hiroshi Kuga, Masahiro Ikeda, Yoshinobu Shiose
  • Publication number: 20030171262
    Abstract: A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.
    Type: Application
    Filed: May 28, 2002
    Publication date: September 11, 2003
    Applicant: Daiichi Pharmaceutical Co., Ltd.
    Inventors: Kazuhiro Inoue, Hiroshi Susaki, Masahiro Ikeda, Hiroshi Kuga, Eiji Kumazawa, Akiko Togo
  • Patent number: 6436912
    Abstract: A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized-in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: August 20, 2002
    Assignees: Daiichi Pharmaceutical Co., Ltd., Drug Delivery System Institute, Ltd.
    Inventors: Kazuhiro Inoue, Hiroshi Susaki, Masahiro Ikeda, Hiroshi Kuga, Eiji Kumazawa, Akiko Togo