Patents by Inventor Hiroshi Kusuoku

Hiroshi Kusuoku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9918930
    Abstract: The present invention provides a processed plant product having an excellent TRPM8 activating action, a method for producing the same, and a cooling agent and a TRPM8 activator comprising the processed plant product. A method for producing a processed nutmeg product, comprising a step of simultaneously treating nutmeg or an extract thereof with an alcohol or a 25% (v/v) or more alcohol aqueous solution and one or more selected from a protonic acid and an H-type cation exchange resin.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: March 20, 2018
    Assignee: KAO CORPORATION
    Inventors: Tomohiro Shirai, Kentaro Kumihashi, Mitsuyoshi Sakasai, Hiroshi Kusuoku, Hiroshi Hashimoto
  • Patent number: 9340478
    Abstract: Provided are a cooling agent having an excellent TRPM8 activating action, a TRPM8 activator, a method for imparting cooling sensation, and a novel compound useful for imparting cooling sensation.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: May 17, 2016
    Assignee: Kao Corporation
    Inventors: Tomohiro Shirai, Hiroshi Kusuoku, Mitsuyoshi Sakasai, Kentaro Kumihashi
  • Patent number: 9222079
    Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: December 29, 2015
    Assignee: KAO CORPORATION
    Inventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
  • Publication number: 20150071865
    Abstract: The present invention provides a processed plant product having an excellent TRPM8 activating action, a method for producing the same, and a cooling agent and a TRPM8 activator comprising the processed plant product. A method for producing a processed nutmeg product, comprising a step of simultaneously treating nutmeg or an extract thereof with an alcohol or a 25% (v/v) or more alcohol aqueous solution and one or more selected from a protonic acid and an H-type cation exchange resin.
    Type: Application
    Filed: July 11, 2013
    Publication date: March 12, 2015
    Applicant: KAO CORPORATION
    Inventors: Tomohiro Shirai, Kentaro Kumihashi, Mitsuyoshi Sakasai, Hiroshi Kusuoku, Hiroshi Hashimoto
  • Publication number: 20140329910
    Abstract: Provided are a cooling agent having an excellent TRPM8 activating action, a TRPM8 activator, a method for imparting cooling sensation, and a novel compound useful for imparting cooling sensation.
    Type: Application
    Filed: November 19, 2012
    Publication date: November 6, 2014
    Applicant: Kao Corporation
    Inventors: Tomohiro Shirai, Hiroshi Kusuoku, Mitsuyoshi Sakasai
  • Patent number: 8790726
    Abstract: Deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient and which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: July 29, 2014
    Assignee: Kao Corporation
    Inventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
  • Patent number: 8197859
    Abstract: To provide a lipolysis agent, a slimming agent, and a cellulite-ameliorating agent, which stimulate decomposition of fat accumulated in the adipose tissue, to thereby exhibit body-slimming effect and which is effective for inhibition or prevention of obesity and amelioration of prone to obesity. The lipolysis stimulator of the invention contains, as effective ingredients, a plant Huang Hua Cai or an extract thereof, and a xanthine derivative.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: June 12, 2012
    Assignee: Kao Corporation
    Inventors: Minoru Takizawa, Mayumi Sato, Hiroshi Kusuoku, Mitsuyoshi Sakasai
  • Publication number: 20110151036
    Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Inventors: Shingo KAKUO, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
  • Patent number: 7887851
    Abstract: Drugs and cosmetics which are highly safe, and which are effective in preventing, improving, or treating various pathological conditions caused by estrogen depletion are provided. Provided are aromatase activators containing at least one member selected from plants such as Labiatae sps. including Isodon, Scutellaria (huangcen), Schizonepeta (jingjie), sage, lavender, Lamium album, and thyme, an extract thereof; yeast extract; silk protein extract; milk protein; trehalose; natto extract; royal jelly; oryza oil; hydrolyzated wheat extract; shea butter; and rice fermentation extract.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: February 15, 2011
    Assignee: Kao Corporation
    Inventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
  • Publication number: 20100285153
    Abstract: To provide a lipolysis agent, a slimming agent, and a cellulite-ameliorating agent, which stimulate decomposition of fat accumulated in the adipose tissue, to thereby exhibit body-slimming effect and which is effective for inhibition or prevention of obesity and amelioration of prone to obesity. The lipolysis stimulator of the invention contains, as effective ingredients, a plant Huang Hua Cai or an extract thereof, and a xanthine derivative.
    Type: Application
    Filed: March 13, 2007
    Publication date: November 11, 2010
    Applicant: Kao Corporation
    Inventors: Minoru Takizawa, Mayumi Sato, Hiroshi Kusuoku, Mitsuyoshi Sakasai
  • Publication number: 20090317346
    Abstract: This invention relates to deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient. According to the present invention, deodorant agents which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: Kao Corporation
    Inventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
  • Patent number: 7504116
    Abstract: The present invention relates to a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri Radix, Perillae Herba, Rhei Rhizoma and Akebiae Caulis, or an extract thereof. This inhibitor or accelerator makes it possible to inhibit the growth of body hair or promote depilation, respectively, thereby reducing the frequency of hair removal treatment. Moreover, it makes the hair body finer, thereby facilitating the removal of the hair from feet or arms.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: March 17, 2009
    Assignee: Kao Corporation
    Inventors: Etsuji Wakisaka, Takashi Kitahara, Naoko Tsuji, Hiroshi Kusuoku
  • Patent number: 7501136
    Abstract: Provided is a deodorant composition containing (A) an extract of a plant selected from phellodendron (Phellodendron amurense or P. chinensis), ginkgo (Ginkgo biloba), Lithospermum erythrorhizon, licorice (Glycyrrhiza glabra) and gardenia (Gardenia jasminoides), and (B) an unsaturated fatty acid. This deodorant composition has benefits such as an excellent deodorant effect and even if it contains powder, it does not leave substantially any white residue on the skin.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: March 10, 2009
    Assignee: Kao Corporation
    Inventors: Toyoki Hagura, Akira Fuji, Shunichi Akiba, Hiroshi Kusuoku
  • Patent number: 7488499
    Abstract: The present invention relates to a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri Radix, Perillae Herba, Rhel Rhizoma and Akebiae Caulis, or an extract thereof. This inhibitor or accelerator makes it possible to inhibit the growth of body hair or promote depilation, respectively, thereby reducing the frequency of hair removal treatment. Moreover, it makes the hair body finer, thereby facilitating the removal of the hair from feet or arms.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: February 10, 2009
    Assignee: Kao Corporation
    Inventors: Etsuji Wakisaka, Takashi Kitahara, Naoko Tsuji, Hiroshi Kusuoku
  • Publication number: 20080021418
    Abstract: The present invention is directed to a lipolysis stimulator and a slimming agent which stimulate or facilitate lipolysis of accumulated adipose tissue, to thereby exert the body slimming effect. The lipolysis stimulator or the slimming agent of the present invention contains as an active ingredient any form of a plant or an extract thereof, the plant being selected from among common juniper, togenashi, rosehip, areca, polygala root, plantago herb, calumba, zuikorodoku, garden nasturtium, kidachiumanosuzukusa, bayberry, cogon grass, kohon, shoyokanzo, Japanese white birch, tanjin, kikubafuro, white mustard, common sunflower, ground ivy, Chinese wolfberry, Japanese pagota tree, sennenken, common fig, kankatto, Chinese hibiscus, usubaakaza, fenugreek, English walnut, sozuku, koniwa-zakura, gardenia, shima-kan-giku, akamino-akane, futaba-mugura, karoou, schizonepeta spike, purslane, karabyakushi, and prostrate knotweed.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Applicant: Kao Corporation
    Inventors: Shinobu Mori, Hiroshi Kusuoku, Mayumi Sato
  • Patent number: 7300675
    Abstract: A lipolysis stimulator and a slimming agent which stimulate or facilitate lipolysis of accumulated adipose tissue, to thereby exert the body slimming effect. The lipolysis stimulator or the slimming agent of the present invention contains as an active ingredient any form of a plant or an extract thereof, the plant being selected from among common juniper, togenashi, rosehip, areca, polygala root, plantago herb, calumba, zuikorodoku, garden nasturtium, kidachiumanosuzukusa, bayberry, cogon grass, kohon, shoyokanzo, Japanese white birch, tanjin, kikubafuro, white mustard, common sunflower, ground ivy, Chinese wolfberry, Japanese pagota tree, sennenken, common fig, kankatto, Chinese hibiscus, usubaakaza, fenugreek, English walnut, sozuku, koniwa-zakura, gardenia, shima-kan-giku, akamino-akane, futaba-mugura, karoou, schizonepeta spike, purslane, karabyakushi, and prostrate knotweed.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: November 27, 2007
    Assignee: Kao Corporation
    Inventors: Shinobu Mori, Hiroshi Kusuoku, Mayumi Sato
  • Publication number: 20070041996
    Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.
    Type: Application
    Filed: October 13, 2006
    Publication date: February 22, 2007
    Applicant: KAO CORPORATION
    Inventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
  • Patent number: 7147877
    Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: December 12, 2006
    Assignee: Kao Corporation
    Inventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
  • Publication number: 20060251596
    Abstract: This invention relates to deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient. According to the present invention, deodorant agents which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.
    Type: Application
    Filed: September 19, 2003
    Publication date: November 9, 2006
    Applicant: Kao Corporation
    Inventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
  • Patent number: 7078437
    Abstract: The invention contemplates drugs useful for maintenance or promotion at sites of regenerating nerves and for prevention or treatment of pathological conditions caused by denaturation or cell damage in the nervous system. Thus, the invention provides an apolipoprotein D degradation inhibitor containing lauric acid or oleic acid as an active ingredient.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: July 18, 2006
    Assignee: Kao Corporation
    Inventors: Shunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Yoshinori Nishizawa