Patents by Inventor Hiroshi Kusuoku
Hiroshi Kusuoku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9918930Abstract: The present invention provides a processed plant product having an excellent TRPM8 activating action, a method for producing the same, and a cooling agent and a TRPM8 activator comprising the processed plant product. A method for producing a processed nutmeg product, comprising a step of simultaneously treating nutmeg or an extract thereof with an alcohol or a 25% (v/v) or more alcohol aqueous solution and one or more selected from a protonic acid and an H-type cation exchange resin.Type: GrantFiled: July 11, 2013Date of Patent: March 20, 2018Assignee: KAO CORPORATIONInventors: Tomohiro Shirai, Kentaro Kumihashi, Mitsuyoshi Sakasai, Hiroshi Kusuoku, Hiroshi Hashimoto
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Patent number: 9340478Abstract: Provided are a cooling agent having an excellent TRPM8 activating action, a TRPM8 activator, a method for imparting cooling sensation, and a novel compound useful for imparting cooling sensation.Type: GrantFiled: November 19, 2012Date of Patent: May 17, 2016Assignee: Kao CorporationInventors: Tomohiro Shirai, Hiroshi Kusuoku, Mitsuyoshi Sakasai, Kentaro Kumihashi
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Patent number: 9222079Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.Type: GrantFiled: December 16, 2010Date of Patent: December 29, 2015Assignee: KAO CORPORATIONInventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
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Publication number: 20150071865Abstract: The present invention provides a processed plant product having an excellent TRPM8 activating action, a method for producing the same, and a cooling agent and a TRPM8 activator comprising the processed plant product. A method for producing a processed nutmeg product, comprising a step of simultaneously treating nutmeg or an extract thereof with an alcohol or a 25% (v/v) or more alcohol aqueous solution and one or more selected from a protonic acid and an H-type cation exchange resin.Type: ApplicationFiled: July 11, 2013Publication date: March 12, 2015Applicant: KAO CORPORATIONInventors: Tomohiro Shirai, Kentaro Kumihashi, Mitsuyoshi Sakasai, Hiroshi Kusuoku, Hiroshi Hashimoto
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Publication number: 20140329910Abstract: Provided are a cooling agent having an excellent TRPM8 activating action, a TRPM8 activator, a method for imparting cooling sensation, and a novel compound useful for imparting cooling sensation.Type: ApplicationFiled: November 19, 2012Publication date: November 6, 2014Applicant: Kao CorporationInventors: Tomohiro Shirai, Hiroshi Kusuoku, Mitsuyoshi Sakasai
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Patent number: 8790726Abstract: Deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient and which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.Type: GrantFiled: August 27, 2009Date of Patent: July 29, 2014Assignee: Kao CorporationInventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
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Patent number: 8197859Abstract: To provide a lipolysis agent, a slimming agent, and a cellulite-ameliorating agent, which stimulate decomposition of fat accumulated in the adipose tissue, to thereby exhibit body-slimming effect and which is effective for inhibition or prevention of obesity and amelioration of prone to obesity. The lipolysis stimulator of the invention contains, as effective ingredients, a plant Huang Hua Cai or an extract thereof, and a xanthine derivative.Type: GrantFiled: March 13, 2007Date of Patent: June 12, 2012Assignee: Kao CorporationInventors: Minoru Takizawa, Mayumi Sato, Hiroshi Kusuoku, Mitsuyoshi Sakasai
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Publication number: 20110151036Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.Type: ApplicationFiled: December 16, 2010Publication date: June 23, 2011Inventors: Shingo KAKUO, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
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Patent number: 7887851Abstract: Drugs and cosmetics which are highly safe, and which are effective in preventing, improving, or treating various pathological conditions caused by estrogen depletion are provided. Provided are aromatase activators containing at least one member selected from plants such as Labiatae sps. including Isodon, Scutellaria (huangcen), Schizonepeta (jingjie), sage, lavender, Lamium album, and thyme, an extract thereof; yeast extract; silk protein extract; milk protein; trehalose; natto extract; royal jelly; oryza oil; hydrolyzated wheat extract; shea butter; and rice fermentation extract.Type: GrantFiled: June 1, 2005Date of Patent: February 15, 2011Assignee: Kao CorporationInventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
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Publication number: 20100285153Abstract: To provide a lipolysis agent, a slimming agent, and a cellulite-ameliorating agent, which stimulate decomposition of fat accumulated in the adipose tissue, to thereby exhibit body-slimming effect and which is effective for inhibition or prevention of obesity and amelioration of prone to obesity. The lipolysis stimulator of the invention contains, as effective ingredients, a plant Huang Hua Cai or an extract thereof, and a xanthine derivative.Type: ApplicationFiled: March 13, 2007Publication date: November 11, 2010Applicant: Kao CorporationInventors: Minoru Takizawa, Mayumi Sato, Hiroshi Kusuoku, Mitsuyoshi Sakasai
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Publication number: 20090317346Abstract: This invention relates to deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient. According to the present invention, deodorant agents which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.Type: ApplicationFiled: August 27, 2009Publication date: December 24, 2009Applicant: Kao CorporationInventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
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Patent number: 7504116Abstract: The present invention relates to a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri Radix, Perillae Herba, Rhei Rhizoma and Akebiae Caulis, or an extract thereof. This inhibitor or accelerator makes it possible to inhibit the growth of body hair or promote depilation, respectively, thereby reducing the frequency of hair removal treatment. Moreover, it makes the hair body finer, thereby facilitating the removal of the hair from feet or arms.Type: GrantFiled: October 27, 2004Date of Patent: March 17, 2009Assignee: Kao CorporationInventors: Etsuji Wakisaka, Takashi Kitahara, Naoko Tsuji, Hiroshi Kusuoku
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Patent number: 7501136Abstract: Provided is a deodorant composition containing (A) an extract of a plant selected from phellodendron (Phellodendron amurense or P. chinensis), ginkgo (Ginkgo biloba), Lithospermum erythrorhizon, licorice (Glycyrrhiza glabra) and gardenia (Gardenia jasminoides), and (B) an unsaturated fatty acid. This deodorant composition has benefits such as an excellent deodorant effect and even if it contains powder, it does not leave substantially any white residue on the skin.Type: GrantFiled: September 27, 2004Date of Patent: March 10, 2009Assignee: Kao CorporationInventors: Toyoki Hagura, Akira Fuji, Shunichi Akiba, Hiroshi Kusuoku
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Patent number: 7488499Abstract: The present invention relates to a hair growth inhibitor and a depilation accelerator, each comprising a crude drug selected from Bupleuri Radix, Perillae Herba, Rhel Rhizoma and Akebiae Caulis, or an extract thereof. This inhibitor or accelerator makes it possible to inhibit the growth of body hair or promote depilation, respectively, thereby reducing the frequency of hair removal treatment. Moreover, it makes the hair body finer, thereby facilitating the removal of the hair from feet or arms.Type: GrantFiled: September 19, 2002Date of Patent: February 10, 2009Assignee: Kao CorporationInventors: Etsuji Wakisaka, Takashi Kitahara, Naoko Tsuji, Hiroshi Kusuoku
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Publication number: 20080021418Abstract: The present invention is directed to a lipolysis stimulator and a slimming agent which stimulate or facilitate lipolysis of accumulated adipose tissue, to thereby exert the body slimming effect. The lipolysis stimulator or the slimming agent of the present invention contains as an active ingredient any form of a plant or an extract thereof, the plant being selected from among common juniper, togenashi, rosehip, areca, polygala root, plantago herb, calumba, zuikorodoku, garden nasturtium, kidachiumanosuzukusa, bayberry, cogon grass, kohon, shoyokanzo, Japanese white birch, tanjin, kikubafuro, white mustard, common sunflower, ground ivy, Chinese wolfberry, Japanese pagota tree, sennenken, common fig, kankatto, Chinese hibiscus, usubaakaza, fenugreek, English walnut, sozuku, koniwa-zakura, gardenia, shima-kan-giku, akamino-akane, futaba-mugura, karoou, schizonepeta spike, purslane, karabyakushi, and prostrate knotweed.Type: ApplicationFiled: July 24, 2007Publication date: January 24, 2008Applicant: Kao CorporationInventors: Shinobu Mori, Hiroshi Kusuoku, Mayumi Sato
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Patent number: 7300675Abstract: A lipolysis stimulator and a slimming agent which stimulate or facilitate lipolysis of accumulated adipose tissue, to thereby exert the body slimming effect. The lipolysis stimulator or the slimming agent of the present invention contains as an active ingredient any form of a plant or an extract thereof, the plant being selected from among common juniper, togenashi, rosehip, areca, polygala root, plantago herb, calumba, zuikorodoku, garden nasturtium, kidachiumanosuzukusa, bayberry, cogon grass, kohon, shoyokanzo, Japanese white birch, tanjin, kikubafuro, white mustard, common sunflower, ground ivy, Chinese wolfberry, Japanese pagota tree, sennenken, common fig, kankatto, Chinese hibiscus, usubaakaza, fenugreek, English walnut, sozuku, koniwa-zakura, gardenia, shima-kan-giku, akamino-akane, futaba-mugura, karoou, schizonepeta spike, purslane, karabyakushi, and prostrate knotweed.Type: GrantFiled: July 28, 2004Date of Patent: November 27, 2007Assignee: Kao CorporationInventors: Shinobu Mori, Hiroshi Kusuoku, Mayumi Sato
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Publication number: 20070041996Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.Type: ApplicationFiled: October 13, 2006Publication date: February 22, 2007Applicant: KAO CORPORATIONInventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
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Patent number: 7147877Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.Type: GrantFiled: December 3, 2003Date of Patent: December 12, 2006Assignee: Kao CorporationInventors: Shingo Kakuo, Shigeru Moriwaki, Atsushi Ohuchi, Hiroshi Kusuoku
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Publication number: 20060251596Abstract: This invention relates to deodorant agents, which contain ginkgo or Phellodendron Bark or its extract as an active ingredient. According to the present invention, deodorant agents which are high in safety and can radically inhibit the emission of human body malodors typified by sweat odor, especially, axillary odor.Type: ApplicationFiled: September 19, 2003Publication date: November 9, 2006Applicant: Kao CorporationInventors: Syunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Toyoki Hagura
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Patent number: 7078437Abstract: The invention contemplates drugs useful for maintenance or promotion at sites of regenerating nerves and for prevention or treatment of pathological conditions caused by denaturation or cell damage in the nervous system. Thus, the invention provides an apolipoprotein D degradation inhibitor containing lauric acid or oleic acid as an active ingredient.Type: GrantFiled: July 27, 2004Date of Patent: July 18, 2006Assignee: Kao CorporationInventors: Shunichi Akiba, Katsutoshi Ara, Hiroshi Kusuoku, Yoshinori Nishizawa