Patents by Inventor Hiroshi Maruoka

Hiroshi Maruoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210238136
    Abstract: An object of the present invention is to provide a compound useful as a therapeutic or prophylactic drug for a disease involving the immune system, by suppressing a function of immune cells by suppressing proliferation of activated T cells or suppressing production of interferon alpha (IFN-?) by activated plasmacytoid dendritic cells (pDC), particularly an autoimmune disease such as systemic lupus erythematosus (SLE) and lupus nephritis in SLE patients. The present invention provides a compound represented by general formula (I): [wherein X, R1, R2, R3, R4, R5 and R6 are as described in the description], or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 6, 2019
    Publication date: August 5, 2021
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Hiroshi Maruoka, Toshiharu Noji, Hidenobu Murafuji, Tomoyuki Tsunemi, Junko Takahashi, Shuhei Uesugi, Urara Tomita
  • Publication number: 20130296551
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 7, 2013
    Inventors: Tsuyoshi MUTO, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori
  • Patent number: 8507714
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: August 13, 2013
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori
  • Patent number: 8049006
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: November 1, 2011
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori, Koji Sato, Tsutomu Yagi
  • Publication number: 20110166342
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 7, 2011
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori
  • Patent number: 7888348
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: February 15, 2011
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori
  • Publication number: 20090253683
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Application
    Filed: May 30, 2007
    Publication date: October 8, 2009
    Applicants: ASUBIO PHARMA CO., LTD, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori, Koji Sato, Tsutomu Yagi
  • Publication number: 20090111796
    Abstract: A 7-membered heterocyclic compound having the formula (I), or its salt, or a solvate thereof with a chymase inhibitory action and useful for the prevention or treatment of various diseases, in which chymase is involved: a method for producing the same, and a pharmaceutical composition useful for the prevention or treatment of diseases, in which chymase is involved, including the compound of having the formula (I), or its pharmaceutically acceptable salt, or a solvate thereof are provided.
    Type: Application
    Filed: December 1, 2005
    Publication date: April 30, 2009
    Inventors: Tsuyoshi Muto, Taisaku Tanaka, Hiroshi Maruoka, Seiichi Imajo, Yoshiaki Tomimori
  • Patent number: 7158243
    Abstract: A printing apparatus can quickly cancel a print job without any influence on the other subsequent print jobs when a print cancel instruction is issued. During printing, if a print cancel instruction is inputted from a printer operation unit, a printer function manager notifies a print command interpreter of the cancellation. The print command interpreter searches data processed at that time in a transmission/reception buffer for an end mark command indicating the end of the cancelled job. Then the print command interpreter deletes the data before the end mark command.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: January 2, 2007
    Assignee: Canon Kabushiki Kaisha
    Inventors: Kazuya Sakamoto, Takayuki Fujita, Tsutomu Takahashi, Mikio Shiga, Hiroshi Maruoka, Tetsuya Kawanabe, Nobuo Onuma, Masao Maeda, Nobuhiro Saito, Shunichi Kunihiro, Takashi Imoto, Kazuhisa Ebuchi
  • Patent number: 7098215
    Abstract: The present invention provides novel compounds having antiviral activities and antiviral drugs containing the compounds as the active ingredient.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 29, 2006
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Toru Yamazaki, Hiroshi Maruoka, Shigeru Suzuki, Tsutomu Mukade, Kunitaka Hirose, Mikiro Yanaka, Naoki Yamamoto
  • Patent number: 6765686
    Abstract: Image data is stored on a removable external card together with previous printing information relating to printing of this image data. Accordingly, when printing identical with that executed previously is carried out, the need to make printing settings again is eliminated by performing printing based upon the stored information. By further storing printing paper information in the external card, information regarding a new type of printing paper can be registered in an image processing apparatus with ease. This makes it possible for the apparatus to print properly even on a new type of paper.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: July 20, 2004
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Maruoka
  • Publication number: 20040092556
    Abstract: The present invention provides novel compounds having antiviral activities and antiviral drugs containing the compounds as the active ingredient.
    Type: Application
    Filed: November 21, 2002
    Publication date: May 13, 2004
    Inventors: Toru Yamazaki, Hiroshi Maruoka, Shigeru Suzuki, Tsutomu Mukade, Kunitaka Hirose, Mikiro Yanaka, Naoki Yamamoto
  • Publication number: 20030137680
    Abstract: Image data is stored on a removable external card together with previous printing information relating to printing of this image data. Accordingly, when printing identical with that executed previously is carried out, the need to make printing settings again is eliminated by performing printing based upon the stored information. By further storing printing paper information in the external card, information regarding a new type of printing paper can be registered in an image processing apparatus with ease. This makes it possible for the apparatus to print properly even on a new type of paper.
    Type: Application
    Filed: November 12, 1998
    Publication date: July 24, 2003
    Inventor: HIROSHI MARUOKA
  • Publication number: 20020021453
    Abstract: A printing apparatus which quickly cancels a print job without any influence on the subsequent other print jobs when a print cancel instruction is issued. During printing, if a print cancel instruction is inputted from a printer operation unit 107, a printer function manager 109 notifies a print command interpreter 108 of the cancellation. The print command interpreter 108 searches data processed at that time in a transmission/reception buffer for an end mark command indicating the end of the cancelled job. Then the print command interpreter 108 deletes the data before the end mark command.
    Type: Application
    Filed: July 13, 2001
    Publication date: February 21, 2002
    Inventors: Kazuya Sakamoto, Takayuki Fujita, Tsutomu Takahashi, Mikio Shiga, Hiroshi Maruoka, Tetsuya Kawanabe, Nobuo Onuma, Masao Maeda, Nobuhiro Saito, Shunichi Kunihiro, Takashi Imoto, Kazuhisa Ebuchi
  • Patent number: 6242445
    Abstract: A novel benzimidazole derivative [specifically, for example, 2-ethoxy-1-[{4′-(2″-N,N-dimethylaminoethoxycarbonyl)phenyl}methyl]-1H-benzimidazole-6-carboxylic acid morpholide] represented by formula (I) and a salt thereof. The compound exhibits satisfactory curative effects for cardiac and nephric diseases, although having little action on blood-pressure.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: June 5, 2001
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Mikiro Yanaka, Shigeru Suzuki, Fuyuhiko Nishijima, Hiroshi Takahashi, Mikio Sugano, Hiroshi Maruoka, Toru Yamazaki, Toshikazu Dewa, Hiroyuki Enari, Michihito Ise
  • Patent number: 5863913
    Abstract: An aromatic compound of the formula (I): ##STR1## specifically, for example, 3-??(4-carboxyphenyl)methyl!valeramido!-4-dimethylaminobenzoic acid 4'-methylpiperazide, or a salt thereof, and a pharmaceutical composition comprising said aromatic compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent which provides sufficiently effective alleviation of renal dysfunction without affecting blood pressure at a low blood concentration.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: January 26, 1999
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Mikiro Yanaka, Hiroyuki Enari, Toru Yamazaki, Hiroshi Maruoka, Toshikazu Dewa, Fuyuhiko Nishijima, Hiroshi Takahashi, Michihito Ise
  • Patent number: 5731293
    Abstract: A compound of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are, independently, --CON(R.sup.4)R.sup.5, or a monosaccharide, or acylated monosaccharide group, with the proviso that at least one of R.sup.1 and R.sup.2 is --CON(R.sup.4)R.sup.5, and R.sup.4 and R.sup.5 are, independently, a hydrogen atom, or a hydroxyl, alkyl, aryl, or aralkyl group, or R.sup.4 and R.sup.5 together with the nitrogen atom attached thereto form a 3- to 7-membered saturated cycloaliphatic amino group, and R.sup.3 is a hydrogen atom, or a hydroxyl, alkyl, aryl, aralkyl, or --COOR.sup.8 group, and R.sup.3 is at 3- or 4-position, and R.sup.8 is a hydrogen atom or an alkyl group, or a salt thereof is disclosed. The compound has a function to inhibit a matrix metalloproteinase.
    Type: Grant
    Filed: December 28, 1995
    Date of Patent: March 24, 1998
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Koju Watanabe, Koichi Niimura, Toru Yamazaki, Hiroshi Maruoka
  • Patent number: 5631980
    Abstract: An image processing apparatus has an image reader, an image memory for storing image data and having an image expanding area for expanding image data, a keyboard for inputting necessary data for editing image data, and a CPU for operating the image data so as to reproduce an image edited in accordance with information input at the keyboard by the operator. Desired areas of an original can be reproduced at desired areas of fan fold paper. When image processing is interrupted during printing, image data already read and stored in a buffer memory can be saved and used for printing when printing is resumed.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: May 20, 1997
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hiroshi Maruoka
  • Patent number: D279190
    Type: Grant
    Filed: January 21, 1983
    Date of Patent: June 11, 1985
    Assignee: Panafacom Limited
    Inventors: Tomoki Tsumura, Hiroshi Maruoka, Toshio Asaji, Mitsuru Yamamoto
  • Patent number: D280900
    Type: Grant
    Filed: January 21, 1983
    Date of Patent: October 8, 1985
    Assignee: Panafacom Limited
    Inventors: Tomoki Tsumura, Hiroshi Maruoka, Toshio Asaji, Mitsuru Yamamoto