Patents by Inventor Hiroshi Masumoto
Hiroshi Masumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210310014Abstract: Gene expression is regulated (ON/OFF switching) by regulating the chromatin structure, and a several tens of genes (multigene) set introduced into genetically modified crops is stably expressed by the regulation. A plant recombinant gene expression regulatory platform DNA sequence comprising (1) an artificial alphoid DNA sequence having a hierarchical repetitive structure of an alphoid DNA that forms a centromere of a human chromosome and having a nucleotide sequence a part of which is replaced by a binding site of a gene expression regulator (inducer); and (2) a multigene (a plurality of genes) expression cassette sequence, wherein the artificial alphoid DNA sequence is linked to upstream (5? side) and downstream (3? side) of the cassette sequence; and a method for regulating the expression of a recombinant gene in a plant body using the sequence.Type: ApplicationFiled: August 5, 2019Publication date: October 7, 2021Applicant: KAZUSA DNA RESEARCH INSTITUTEInventors: Hiroshi MASUMOTO, Daisuke SHIBATA, Jun-ichirou OHZEKI, Koei OKAZAKI, Kazuto KUGOU, Koichiro OTAKE, Jekson ROBERTLEE
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Patent number: 9214824Abstract: A charging control apparatus controls charging of a battery connected to a battery terminal and supplies a voltage and a current necessary for a system circuit through an output terminal. The charging control apparatus has a switching control circuit that controls a DC-DC converter, the DC-DC converter performing DC-DC conversion with respect to an input voltage input through an input terminal and outputting an obtained output voltage to the output terminal. The charging control apparatus has an output voltage detection circuit that detects the output voltage. The charging control apparatus has a battery voltage detection circuit that detects a battery voltage of the battery terminal. The charging control apparatus has a first switch MOS transistor connected between the output terminal and the battery terminal. The charging control apparatus has a voltage control circuit that controls an operation of the first switch MOS transistor according to the battery voltage.Type: GrantFiled: March 22, 2011Date of Patent: December 15, 2015Assignee: Kabushiki Kaisha ToshibaInventors: Hiroshi Masumoto, Shigehito Saigusa
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Patent number: 9139849Abstract: Methods are described for construction of long synthetic arrays of DNA repeats, such as alphoid repeats or other repeat sequences. The methods include concatamerization of DNA into short repeats (for instance using rolling circle amplification or directional in vitro ligation), followed by assembling the short repeats into long arrays by homologous recombination during transformation into microbe cells. These methods can be described generally as Recombinational Amplification of Repeats (RAR). The long arrays are engineered centromere-like regions that allow one to construct mammalian artificial chromosomes with a predefined centromeric region structure. Artificial chromosomes, including human artificial chromosomes with a regulated centromere, and methods of their use are also provided.Type: GrantFiled: April 7, 2006Date of Patent: September 22, 2015Assignees: The United States of America as Represented by the Government of the Department of Health and Human Services, The University Court of the University of EdinburghInventors: Vladimir L. Larionov, William C. Earnshaw, Reto Gassman, Stefanie Kandels-Lewis, Hiroshi Masumoto, Megumi Nakano, Vladimir Noskov, Natalay Y. Kouprina, Carl J. Barrett, Stefano Cardinale
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Patent number: 8323142Abstract: A multi-speed transmission includes a first input shaft, a second input shaft, a first friction engagement mechanism, a second friction engagement mechanism, a first synchromesh mechanism, a second synchromesh mechanism, and a third friction engagement mechanism. A differential mechanism includes a first rotational element, a second rotational element, and a third rotational element. The first rotational element is coupled to a first countershaft. The second rotational element is coupled to a second countershaft. The third rotational element is coupled to an output member. A third synchromesh mechanism is capable of coupling a driving gear of a first gear train to the first input shaft or is capable of coupling a driven gear of the first gear train to the output member so as to enable power to be transferred between the first input shaft and the output member using the first gear train.Type: GrantFiled: April 27, 2011Date of Patent: December 4, 2012Assignee: Honda Motor Co., Ltd.Inventor: Hiroshi Masumoto
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Publication number: 20120133340Abstract: A charging control apparatus controls charging of a battery connected to a battery terminal and supplies a voltage and a current necessary for a system circuit through an output terminal. The charging control apparatus has a switching control circuit that controls a DC-DC converter, the DC-DC converter performing DC-DC conversion with respect to an input voltage input through an input terminal and outputting an obtained output voltage to the output terminal. The charging control apparatus has an output voltage detection circuit that detects the output voltage. The charging control apparatus has a battery voltage detection circuit that detects a battery voltage of the battery terminal. The charging control apparatus has a first switch MOS transistor connected between the output terminal and the battery terminal. The charging control apparatus has a voltage control circuit that controls an operation of the first switch MOS transistor according to the battery voltage.Type: ApplicationFiled: March 22, 2011Publication date: May 31, 2012Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroshi Masumoto, Shigehito Saigusa
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Patent number: 8115458Abstract: A driver includes a sensor sensing a driving current and a driving voltage for an external device including a capacitor, a PWM, a PFC, and a controller. The PFC includes a phase angle estimation unit estimating a phase angle variation of an input voltage to the PFC based on a parameter regarding the driving current, a voltage compensator compensating an error of the driving voltage, a first current estimation unit estimating a variation of a charge of the capacitor based on the charge current and the phase angle variation estimated by the phase angle estimation unit, a second current estimation unit estimating a driving current variation, and a calculator calculating a duty ratio for the PWM based on the variation of the charge current estimated by the first current estimation unit and the driving current variation estimated by the second current estimation unit.Type: GrantFiled: March 15, 2010Date of Patent: February 14, 2012Assignee: Kabushiki Kaisha ToshibaInventors: Yuki Kamata, Hiroshi Masumoto, Hiroshi Nagai, Sadao Ikeda
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Publication number: 20110306458Abstract: A multi-speed transmission includes a first input shaft, a second input shaft, a first friction engagement mechanism, a second friction engagement mechanism, a first synchromesh mechanism, a second synchromesh mechanism, and a third friction engagement mechanism. A differential mechanism includes a first rotational element, a second rotational element, and a third rotational element. The first rotational element is coupled to a first countershaft. The second rotational element is coupled to a second countershaft. The third rotational element is coupled to an output member. A third synchromesh mechanism is capable of coupling a driving gear of a first gear train to the first input shaft or is capable of coupling a driven gear of the first gear train to the output member so as to enable power to be transferred between the first input shaft and the output member using the first gear train.Type: ApplicationFiled: April 27, 2011Publication date: December 15, 2011Applicant: HONDA MOTOR CO., LTD.Inventor: Hiroshi MASUMOTO
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Publication number: 20110089912Abstract: A driver includes a sensor sensing a driving current and a driving voltage for an external device including a capacitor, a PWM, a PFC, and a controller. The PFC includes a phase angle estimation unit estimating a phase angle variation of an input voltage to the PFC based on a parameter regarding the driving current, a voltage compensator compensating an error of the driving voltage, a first current estimation unit estimating a variation of a charge of the capacitor based on the charge current and the phase angle variation estimated by the phase angle estimation unit, a second current estimation unit estimating a driving current variation, and a calculator calculating a duty ratio for the PWM based on the variation of the charge current estimated by the first current estimation unit and the driving current variation estimated by the second current estimation unit.Type: ApplicationFiled: March 15, 2010Publication date: April 21, 2011Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Yuki Kamata, Hiroshi Masumoto, Hiroshi Nagai, Sadao Ikeda
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Publication number: 20100226149Abstract: An embodiment of the invention provides a converter power-supply apparatus that is efficiently operable for a wide-range load. A power-supply control device controls a boost converter. The boost converter includes a basic switching circuit, an expansion switching circuit that is connected in parallel with the basic switching circuit. A control circuit supplies a control signal to the basic and the expansion switching circuit through a first and a second signal line, respectively. A detecting unit detects a voltage and/or a current in a predetermined point of the boost converter. A comparison circuit compares a detected value with a reference value and supplies a first signal when a load is relatively heavy, a second signal when the load is relatively light. A control signal switch connects the second signal line when receiving the first signal, and disconnects the second signal line when receiving the second signal.Type: ApplicationFiled: December 1, 2009Publication date: September 9, 2010Applicant: KABUSHIKI KAISHA TOSHIBAInventor: Hiroshi Masumoto
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Publication number: 20090136924Abstract: Methods are described for construction of long synthetic arrays of DNA repeats, such as alphoid repeats or other repeat sequences. The methods include concatamerization of DNA into short repeats (for instance using rolling circle amplification or directional in vitro ligation), followed by assembling the short repeats into long arrays by homologous recombination during transformation into microbe cells. These methods can be described generally as Recombinational Amplification of Repeats (RAR). The long arrays are engineered centromere-like regions that allow one to construct mammalian artificial chromosomes with a predefined centromeric region structure.Type: ApplicationFiled: April 8, 2006Publication date: May 28, 2009Inventors: Vladimir L. Larionov, William C. Earnshaw, Reto Gassman, Stefanie Kandels-Lewis, Hiroshi Masumoto, Megumi Nakano, Stefano Cardinale, Carl J Barrett, Vladimir Noskov, Natalay Y. Kouprina
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Publication number: 20050020298Abstract: A radio communication apparatus includes a first transmission and reception section that executes process of receiving and transmitting a signal with a first frequency band, a second transmission and reception section that executes process of receiving and transmitting a signal with a second frequency band, and a control circuit that sets, in an operation mode, one of the respective transmission and reception sections which uses a frequency band with which a signal is transmitted and received, while setting the other transmission and reception sections in a stop mode.Type: ApplicationFiled: June 9, 2004Publication date: January 27, 2005Inventors: Hiroshi Masumoto, Tsuneo Suzuki
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Patent number: 6569643Abstract: A mammalian chromosome is produced according to the method comprising the steps of introducing a DNA construct comprising a mammalian telomere and a centromere into a mammalian cell, wherein the centromere has a DNA sequence containing a plurality of copies of the CENP-B box sequence consisting of: 5′-NTTCGNNNNANNCGGGN-3′, wherein N is any one of A, T, C and G.Type: GrantFiled: December 22, 2000Date of Patent: May 27, 2003Inventors: Tsuneko Okazaki, Hiroshi Masumoto, Masashi Ikeno, Howard J. Cooke, Brenda Rose Grimes
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Publication number: 20030027538Abstract: A receiving apparatus comprising a gain control amplifier, a gain controller and a level detection circuit. The gain controller controls a gain of the gain control amplifier. The level detection circuit specifies a range of strengths of received signals based on a signal coupled to an input of the gain control amplifier. The gain controller controls the gain of the gain control amplifier based on the range of the strengths of the received signals.Type: ApplicationFiled: July 26, 2002Publication date: February 6, 2003Inventors: Hiroshi Masumoto, Tsuneo Suzuki
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Patent number: 6456143Abstract: A frequency multiplier circuit comprises: a source oscillator configured to generate a source oscillator signal using a crystal oscillator; and n frequency multiplier circuits (n is an integer which is 2 or more), each of which includes a 90° phase shifter circuit configured to shift the phase of an input signal by 90°, and a mixer configured to generate a doubled signal of the input signal on the basis of the input signal and an output signal of the 90° phase shifter circuit, wherein the n frequency multiplier circuits are cascade-connected, the source oscillation signal being inputted to a first stage frequency multiplier circuit of the n frequency multiplier circuits, and a final stage frequency multiplier circuit of the n frequency multiplier circuits outputting a signal having a frequency 2n times as high as the frequency of the source oscillation signal.Type: GrantFiled: April 27, 2001Date of Patent: September 24, 2002Assignee: Kabushiki Kaisha ToshibaInventors: Hiroshi Masumoto, Tsuneo Suzuki, Teruo Imayama
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Publication number: 20020076811Abstract: A mammalian chromosome is produced according to the method comprising the steps of introducing a DNA construct comprising a mammalian telomere and a centromere into a mammalian cell, wherein the centromere has a DNA sequence containing a plurality of copies of the CENP-B box sequence consisting of: 5′-NTTCGNNNNANNCGGGN-3′, wherein N is any one of A, T, C and G.Type: ApplicationFiled: December 22, 2000Publication date: June 20, 2002Inventors: Tsuneko Okazaki, Hiroshi Masumoto, Masashi Ikeno, Howard J. Cooke, Brenda Rose Grimes
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Publication number: 20010043109Abstract: A frequency multiplier circuit comprises: a source oscillator configured to generate a source oscillator signal using a crystal oscillator; and n frequency multiplier circuits (n is an integer which is 2 or more), each of which includes a 90° phase shifter circuit configured to shift the phase of an input signal by 90°, and a mixer configured to generate a doubled signal of the input signal on the basis of the input signal and an output signal of the 90° phase shifter circuit, wherein the n frequency multiplier circuits are cascade-connected, the source oscillation signal being inputted to a first stage frequency multiplier circuit of the n frequency multiplier circuits, and a final stage frequency multiplier circuit of the n frequency multiplier circuits outputting a signal having a frequency 2n times as high as the frequency of the source oscillation signal.Type: ApplicationFiled: April 27, 2001Publication date: November 22, 2001Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroshi Masumoto, Tsuneo Suzuki, Teruo Imayama
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Patent number: 6297029Abstract: A mammalian chromosome is produced according to the method comprising the steps of: introducing a DNA construct comprising a mammalian telomere and a centromere into a mammalian cell, wherein the centromere has a DNA sequence containing a plurality of copies of the CENP-B box sequence consisting of: 5′-NTTCGNNNNANNCGGGN-3′, wherein N is any one of A, T, C and G.Type: GrantFiled: September 28, 1999Date of Patent: October 2, 2001Inventors: Tsuneko Okazaki, Hiroshi Masumoto, Masashi Ikeno, Howard J. Cooke, Brenda Rose Grimes
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Patent number: 6115180Abstract: Described herein is an optical multilayered-film filter which provides less interference and a good optical characteristic and is high in productivity. The optical multilayered-film filter wherein dielectric thin films are stacked on each other in a multilayer form in a single direction, comprises a refractive-index inclined laminated portion in which refractive indices of dielectric thin-film layers are successively inclined and changed in a laminating direction, and an alternately-laminated portion in which a dielectric thin-film layer having a high refractive index and a dielectric thin-film layer having a low refractive index are alternately laminated on each other.Type: GrantFiled: June 17, 1999Date of Patent: September 5, 2000Assignee: ALPS Electric Co., Ltd.Inventors: Toshio Hirai, Hiroshi Masumoto, Xinrong Wang, Yoshihiro Someno
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Patent number: 5813939Abstract: In a vehicle drive system having a torque split arrangement, it is difficult to have all the rotating parts of the system to be properly balanced. In particular, when a rotational speed difference is produced between the two output elements, relatively massive parts which may not be properly balanced may have to be turned at a high speed. According to the present invention, because the power output of the engine is reduced whenever any significant speed difference is produced between the two output elements, no part of the drive system is subjected to any excessive rotational speed, and are therefore not required to have any excessive mechanical strength. This improves the reliability of the system, and reduces the manufacturing cost.Type: GrantFiled: March 31, 1997Date of Patent: September 29, 1998Assignee: Honda Giken Kogyo Kabushiki KaishaInventors: Hiroshi Masumoto, Sunao Ishihara, Shinji Ohkuma
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Patent number: 5567882Abstract: The pressure sensor comprises an air-tight vacuum chamber consisting of a hollow cylinder and a pressure-reception diaphragm. The pressure-reception diaphragm is provided to face a space communicating with a space of an object to be measured. A field emission cold cathode device is provided on the inner surface of the pressure-reception diaphragm. The cold cathode device comprises a lot of emitter electrodes arranged in a matrix manner for emitting electrons, and gate electrodes for drawing out electrons. Two anode electrodes facing the cold cathode device are provided on the inner end surface of the cylinder. The anode electrodes are connected to a differential amplifier for amplifying a variation in output distribution between them.Type: GrantFiled: September 11, 1995Date of Patent: October 22, 1996Assignee: Kabushiki Kaisha ToshibaInventors: Kouichi Ichimura, Masayuki Nakamoto, Masao Obama, Hiroshi Masumoto