Patents by Inventor Hiroshi MUKAE

Hiroshi MUKAE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREDICTING EFFECT OF IMMUNE CHECKPOINT INHIBITOR
    Publication number: 20220011297
    Abstract: A method may predict risk of onset of severe interstitial pneumonia caused by an immune checkpoint inhibitor to achieve a safe and highly effective cancer immunotherapy. Any one or more selected from: (a) cell count or proportion of V?2+?? T cells in peripheral blood mononuclear cells isolated from a subject; (b) cell count or proportion of V?2+?? T cells after antigenic stimulation in peripheral blood mononuclear cells isolated from a subject; (c) cell count or proportion of V?2+?? T cells in peripheral blood T cells isolated from a subject; and (d) cell count or proportion of V?2+?? T cells after antigenic stimulation in peripheral blood T cells isolated from a subject are measured, and the risk of onset of severe interstitial pneumonia is predicted by using the cell count or proportion as an index.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 13, 2022
    Applicants: NAGASAKI UNIVERSITY, Foundation for Biomedical Research and Innovation at Kobe
    Inventors: Yoshimasa TANAKA, Hiroaki SENJU, Hiroshi MUKAE, Masanori FUKUSHIMA