Abstract: Provided is a package that suppresses stimulation of a corner portion formed after being individually divided. The package includes a first resin sheet including an accommodating portion that is a first recess in which an accommodated object is accommodated, and a second resin sheet covering the accommodating portion and having a welded region that faces the first resin sheet and is welded to the first resin sheet around the accommodating portion. At a corner portion in which a first side in a first direction appearing on a side surface of the welded region and a second side in a second direction appearing on the side surface of the welded region intersect, a non-welded region where the first resin sheet and the second resin sheet are not welded is provided. In the non-welded region, a gap is provided between a corner portion of the first resin sheet and a corner portion of the second resin sheet.

Abstract: Disease model pigs produced by nuclear transplantation, disease model pigs exhibiting stable phenotypes and production methods thereof are provided. Chimeric pigs for producing disease model pigs exhibiting stable phenotypes, genital glands thereof, and germ cells thereof are also provided. A method for producing a genetically modified disease model pig, includes: (a) transplanting a nucleus of a genetically modified cell into cytoplasm of an egg; (b) developing an obtained clonal embryo in a womb of a female pig to obtain an offspring; and mating the obtained offspring or having the offspring undergo sexual reproduction to further obtain the genetically modified offspring as a disease model pig.

Abstract: Provided is a method for developing a secondary organ by using a non-human animal in which organ formation is inhibited, for the purpose of establishing a process for producing a functional cell such as a ? cell within the body of an animal such as a pig, the method including the step of raising a newborn or a fetus of the non-human animal in which organ formation is inhibited by complementing at least a part of the function of the organ whose formation is inhibited.

Abstract: Provided is a method for developing a secondary organ by using a non-human animal in which organ formation is inhibited, for the purpose of establishing a process for producing a functional cell such as a ? cell within the body of an animal such as a pig, the method including the step of raising a newborn or a fetus of the non-human animal in which organ formation is inhibited by complementing at least a part of the function of the organ whose formation is inhibited.

Abstract: Provided is a method for developing a secondary organ by using a non-human animal in which organ formation is inhibited, for the purpose of establishing a process for producing a functional cell such as a ? cell within the body of an animal such as a pig, the method including the step of raising a newborn or a fetus of the non-human animal in which organ formation is inhibited by complementing at least a part of the function of the organ whose formation is inhibited.

Abstract: An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.

Abstract: Provided are 1) a hollow fiber cryopreservation instrument having a long support on which a hollow fiber is placed, wherein the support is formed of a low-temperature-resistant material, and 2) a cell cryopreservation method having a process of placing a hollow fiber on the support of the hollow fiber cryopreservation instrument, and a process of cryopreserving cells in a state in which the hollow fiber is placed on the support.

Abstract: Disease model pigs produced by nuclear transplantation, disease model pigs exhibiting stable phenotypes and production methods thereof are provided. Chimeric pigs for producing disease model pigs exhibiting stable phenotypes, genital glands thereof, and germ cells thereof are also provided. A method for producing a genetically modified disease model pig, includes: (a) transplanting a nucleus of a genetically modified cell into cytoplasm of an egg; (b) developing an obtained clonal embryo in a womb of a female pig to obtain an offspring; and mating the obtained offspring or having the offspring undergo sexual reproduction to further obtain the genetically modified offspring as a disease model pig.

Abstract: A frequency stabilizing apparatus includes a power detecting method control amount calculator, a frequency detecting method control amount calculator, and a command value calculator. The power detecting method control amount calculator generates a first command value based on demand and supply imbalance of power in an isolated island system. The frequency detecting method control amount calculator generates a second command value based on a change in a frequency of the power in the isolated island system. The command value calculator generates a command value to be given to a first storage battery based on the first command value and the second command value.

Abstract: Provided is a sound insulation structure for an internal combustion engine that facilitates the assembly work, and minimizes the transmission vibrations and noises. The sound insulation structure for an internal combustion engine comprises a cover main body (21) disposed outside of a main body (10) of the internal combustion engine and covering at least a part of the engine main body, and a foam sound insulation member (22) made of a foam material and attached to an inner surface (21a) of the cover main body facing the engine main body. The foam sound insulation member covers a noise source (11) of the engine main body and abuts the engine main body or a component part (12, 14) attached to the engine main body at an outer periphery thereof so as to interpose the noise source.

Abstract: Provided are 1) a hollow fiber cryopreservation instrument having a long support on which a hollow fiber is placed, wherein the support is formed of a low-temperature-resistant material, and 2) a cell cryopreservation method having a process of placing a hollow fiber on the support of the hollow fiber cryopreservation instrument, and a process of cryopreserving cells in a state in which the hollow fiber is placed on the support.

Abstract: An organ for transplantation having a kidney, a ureter, and a urinary bladder and an organ structure in which a first ureter, a first urinary bladder, a second ureter and a second urinary bladder are sequentially connected to a kidney can produce urine and excrete the produced urine, and thus is useful for transplantation.

Abstract: A frequency stabilizing apparatus includes a power detecting method control amount calculator, a frequency detecting method control amount calculator, and a command value calculator. The power detecting method control amount calculator generates a first command value based on demand and supply imbalance of power in an isolated island system. The frequency detecting method control amount calculator generates a second command value based on a change in a frequency of the power in the isolated island system. The command value calculator generates a command value to be given to a first storage battery based on the first command value and the second command value.

Abstract: A hydroxyapatite ceramic hybrid material, which includes a biodegradable polymer included in the pores in a hydroxyapatite ceramic structure, and a method thereof, and a calcium phosphate porous body, which is formed by an intertwining of fibrous calcium phosphates and includes a plurality of first pores formed where the fibrous calcium phosphates interconnect and plurality of equal diameter substantially spherical second pores with a larger inside diameter than the first pores, and a method thereof are provided.

Abstract: A hydroxyapatite ceramic hybrid material, which includes a biodegradable polymer included in the pores in a hydroxyapatite ceramic structure, and a method thereof, and a calcium phosphate porous body, which is formed by an intertwining of fibrous calcium phosphates and includes a plurality of first pores formed where the fibrous calcium phosphates interconnect and plurality of equal diameter substantially spherical second pores with a larger inside diameter than the first pores, and a method thereof are provided.

Abstract: The present invention provides a method of evaluating the possibility of a stem cell being able to differentiate into a cell that constitutes a desired tissue in a living organism, comprising the following steps of: (1) transplanting a stem cell to be evaluated into a primordium of a desired tissue of a non-human mammal, (2) culturing the tissue primordium in vitro, and (3) determining the possibility that the stem cell differentiates into a cell that constitutes the tissue in a living organism, with the degree of the dispersion of cells derived from the transplanted stem cell in the cultured tissue primordium as an index.