Patents by Inventor Hiroshi Nakakimura

Hiroshi Nakakimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dibenzoxazepine derivative, and pharmaceutical composition comprising the same
    Patent number: 4435391
    Abstract: Dibenzoxazepine derivatives of the formula: ##STR1## wherein R.sub.1, n, R.sub.2 and R.sub.3 are as defined in the description, process for preparing the same, pharmaceutical composition containing the same and method of treating diseases in circulatory organs administering the composition to a patient are disclosed.The compounds of the formula have lipid lowering activity, lipid peroxide lowering activity, blood sugar lowering activity and activity to inhibit the aggregation of platelets, and hence are useful as a medicine.
    Type: Grant
    Filed: March 4, 1982
    Date of Patent: March 6, 1984
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kazuo Sasahara, Masamitsu Honda, Masuo Koizumi, Yasushi Murakami, Tomohiro Neichi, Hiroshi Nakakimura, Yukifumi Noda, Hiroshi Matsushita, Shun-ichi Hata
  • Nicotinamide derivative, process for preparing the same and pharmaceutical composition containing the same
    Patent number: 4366161
    Abstract: Novel compound, 1,2-bis(nicotinamido)propane and its pharmaceutically acceptable salts, a process for preparing the same and a pharmaceutical composition containing the same as an active ingredient are disclosed.The compound acts to prevent or spasmolyse cerebral vasospasms, to prevent cerebral apoplexy and to lower the lipoperoxide level in blood.
    Type: Grant
    Filed: November 17, 1980
    Date of Patent: December 28, 1982
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takashi Mori, Sakae Takaku, Fumiaki Matsuura, Yasushi Murakami, Yukifumi Noda, Tamotsu Yamazaki, Tomohiro Neichi, Hiroshi Nakakimura, Shigeyuki Kataoka, Takashi Matsuno, Shun-ichi Hata, Shigeru Takanashi
  • Benzoxazepine derivatives and process for preparing the same
    Patent number: 4290953
    Abstract: Dibenz[b,f][1,4]oxazepine derivatives represented by the formula ##STR1## [wherein R.sub.1, n, R.sub.2 and R.sub.3 are as defined in the specification], and a process for preparing the same are disclosed. The object compounds have excellent serum cholesterol lowering activity, serum lipid lowering activity, blood lipid peroxide lowering activity and anti-aggregation of platelet activity, and therefore are useful as a drug.
    Type: Grant
    Filed: December 5, 1979
    Date of Patent: September 22, 1981
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Masuo Koizumi, Kazuo Sasahara, Yasushi Murakami, Sakae Wada, Hiroshi Nakakimura, Noboru Kubodera, Shun-Ichi Hata