Patents by Inventor Hiroshi Nakejima

Hiroshi Nakejima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing diadenosine tetraphosphate and derivatives thereof
    Patent number: 4886749
    Abstract: A process for producing diadenosine tetraphosphate or derivatives thereof in very high yields with little formation of undesired by-products is disclosed. The process comprises reacting adenosine-5'-triphosphate or a derivative thereof with an amino acid under the catalytic action of an aminoacyl-tRNA synthetase in the presence of an enzyme that converts adenosine-5'-diphosphate to adenosine-5'-triphosphate. The formation of by-products can be substantially completely inhibited if the last-mentioned enzyme is used in combination with an enzyme that converts adenosine-5'-monophosphate to adenosine-5'-diphosphate.
    Type: Grant
    Filed: May 28, 1987
    Date of Patent: December 12, 1989
    Assignee: Unitika Ltd.
    Inventors: Munehiko Dombou, Isao Tomioka, Senji Kitabatake, Hiroshi Nakejima