Patents by Inventor Hiroshi Nimura

Hiroshi Nimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964083
    Abstract: This extracorporeal circulation cassette is provided with: a blood circuit (10) comprising a flexible tube and having a blood tube access portion set in a predetermined position in a device; a dialysate circuit (12) comprising a flexible tube and having a dialysate tube access portion set in a predetermined position in the device; a first panel (4) and a second panel (6) that are rigid and that integrate the blood circuit (10) and the dialysate circuit (12) while sandwiching the blood circuit (10) and the dialysate circuit (12) from both sides; and a window portion formed in a part of at least one of the first panel (4) and the second panel (6), disposed in a predetermined position in the device. The blood tube access portion and the dialysate tube access portion are positioned in the window portion.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: April 23, 2024
    Assignee: NIKKISO CO., LTD.
    Inventors: Hiroshi Nimura, Yoshimichi Masuda, Masato Fujiwara
  • Patent number: 11918717
    Abstract: A blood purification device includes a device body and a cassette. The cassette includes: a casing that accommodates a removal water receptacle; and pump tube. The device body includes fingers, a driving unit, and a housing. The cassette can be attached to and removed from the housing of the device body so that the pump tubes are positioned between the plurality of fingers and the outer surfaces of the casing.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: March 5, 2024
    Assignee: NIKKISO CO., LTD.
    Inventors: Takayoshi Yokoyama, Masato Fujiwara, Hiroshi Nimura
  • Publication number: 20230158219
    Abstract: A method for regenerating an adsorber which has a porous body and does not have an enzyme includes a dialysis step, in which the adsorber is connected to a dialysate circulation unit to cause uremic substances within a dialysate to be adsorbed onto the adsorber, and a regenerating step, in which the uremic substances which are adsorbed on the adsorber are desorbed by regenerating water that flows in a regenerating water flow unit. A dialysis system is equipped with the dialysate circulation unit, the adsorber, which is connected to the dialysate circulation unit, and the regenerating water flow unit. The regenerating water flow unit is connectable to the adsorber.
    Type: Application
    Filed: January 24, 2023
    Publication date: May 25, 2023
    Inventors: Masato Fujiwara, Hiroshi Nimura, Takayoshi Yokoyama
  • Patent number: 11590334
    Abstract: An adapter set that is attached to artery-side and vein-side shunt connectors-that are provided on a blood circuit. The adapter set includes: an artery-side adapter that has one end thereof connected to the artery-side shunt connector, has the other end thereof connected to a drainage port that is provided on the outside of the blood circuit, and thereby connects the artery-side shunt connector and the drainage port fluid tight; and a vein-side adapter that has one end thereof connected to the vein-side shunt connector, has the other end thereof connected to a supply port that is provided on the outside of the blood circuit, and thereby connects the vein-side shunt connector and the supply port fluid tight. The structure of the other end of the artery-side adapter and the structure of the other end of the vein-side adapter are different.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: February 28, 2023
    Assignee: NIKKISO CO., LTD.
    Inventors: Hiroshi Nimura, Yoshimichi Masuda, Masato Fujiwara
  • Patent number: 11583619
    Abstract: A method for regenerating an adsorber which has a porous body and does not have an enzyme includes a dialysis step, in which the adsorber is connected to a dialysate circulation unit to cause uremic substances within a dialysate to be adsorbed onto the adsorber, and a regenerating step, in which the uremic substances which are adsorbed on the adsorber are desorbed by regenerating water that flows in a regenerating water flow unit. A dialysis system is equipped with the dialysate circulation unit, the adsorber, which is connected to the dialysate circulation unit, and the regenerating water flow unit. The regenerating water flow unit is connectable to the adsorber.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: February 21, 2023
    Assignee: Nikkiso Co., Ltd.
    Inventors: Masato Fujiwara, Hiroshi Nimura, Takayoshi Yokoyama
  • Patent number: 11446418
    Abstract: A dialysate solution container includes a flexible first bag body. The dialysate solution container further includes a second bag body which has a mixing region for mixing a first powdered pharmaceutical agent and water at a lower end portion of a second interior. The second bag body further has a communication pipe that places the exterior of the second bag body and the second interior in communication, and a first filter which is in communication with a first interior of the first bag body. A first end of the communication pipe is capable of being connected to a dialysis circuit, and a second end thereof is disposed within the mixing region.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: September 20, 2022
    Assignee: Nikkiso Co., Ltd.
    Inventors: Hiroshi Nimura, Masato Fujiwara, Takayoshi Yokoyama
  • Patent number: 11351293
    Abstract: A blood purification device used with a blood circuit includes an arterial-side line and a venous-side line attached to a blood purifier to which, at the ends thereof, the arterial-side line and the venous-side line are connected, the blood purification device including: a supply line connected to a supply unit which supplies a priming fluid, and which is capable of being connected to a leading end of the venous-side line; a discharge line connected to a discharge unit which discharges the priming fluid after use, and which is capable of being connected to a leading end of the arterial-side line; and a blood pump which is disposed upon the arterial-side line. By driving the blood pump in a state of the supply line being connected to the venous-side line and the discharge line being connected to the arterial-side line, the blood circuit and the blood purifier are primed.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: June 7, 2022
    Assignee: NIKKISO CO., LTD.
    Inventors: Hiroshi Nimura, Yoshimichi Masuda, Masato Fujiwara
  • Publication number: 20210316055
    Abstract: A lid that retains a pump tube which is elastic; a finger driving unit that is disposed facing the lid with the pump tube interposed therebetween, and that causes a plurality of fingers to sequentially move in the direction of contacting and separating from the lid; and a pump tube opening/closing mechanism that causes the finger driving unit to advance towards and retract from the lid, and that closes and opens the pump tube which is disposed between the fingers and the lid.
    Type: Application
    Filed: August 27, 2019
    Publication date: October 14, 2021
    Applicant: NIKKISO CO., LTD.
    Inventors: Takayoshi YOKOYAMA, Masato FUJIWARA, Hiroshi NIMURA
  • Publication number: 20210170085
    Abstract: A blood purification device includes a device body and a cassette. The cassette includes: a casing that accommodates a removal water receptacle; and pump tube. The device body includes fingers, a driving unit, and a housing. The cassette can be attached to and removed from the housing of the device body so that the pump tubes are positioned between the plurality of fingers and the outer surfaces of the casing.
    Type: Application
    Filed: August 27, 2019
    Publication date: June 10, 2021
    Applicant: NIKKISO CO., LTD.
    Inventors: Takayoshi YOKOYAMA, Masato FUJIWARA, Hiroshi NIMURA
  • Publication number: 20200360588
    Abstract: A method for regenerating an adsorber which has a porous body and does not have an enzyme includes a dialysis step, in which the adsorber is connected to a dialysate circulation unit to cause uremic substances within a dialysate to be adsorbed onto the adsorber, and a regenerating step, in which the uremic substances which are adsorbed on the adsorber are desorbed by regenerating water that flows in a regenerating water flow unit. A dialysis system is equipped with the dialysate circulation unit, the adsorber, which is connected to the dialysate circulation unit and the regenerating water flow unit. The regenerating water flow unit is connectable to the adsorber.
    Type: Application
    Filed: November 27, 2018
    Publication date: November 19, 2020
    Inventors: Masato Fujiwara, Hiroshi Nimura, Takayoshi Yokoyama
  • Patent number: 10814055
    Abstract: This dialysis-fluid supply system, which mixes a diluent and at least two drugs to generate a dialysis fluid, and outputs said dialysis fluid, is provided with: two tanks which mix the drugs and the diluent to generate the dialysis fluid, and store said dialysis fluid; a water supply device and a drug supply device which supply the diluent and the drugs to each of the tanks; mechanisms for outputting, to a dialysis device, the dialysis fluid stored in each of the tanks; and a control unit for controlling the driving of these. During output of the dialysis fluid from at least one of the tanks, the control unit sequentially switches the supply destination tank for the drugs and the diluent, and the dialysis-fluid output source tank, between the two tanks in order to generate the dialysis fluid in the other tank.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: October 27, 2020
    Assignee: NIKKISO CO., LTD.
    Inventors: Masato Fujiwara, Yoshimichi Masuda, Hiroshi Nimura
  • Publication number: 20200324036
    Abstract: A dialysate solution container includes a flexible first bag body. The dialysate solution container further includes a second bag body which has a mixing region for mixing a first powdered pharmaceutical agent and water at a lower end portion of a second interior. The second bag body further has a communication pipe that places the exterior of the second bag body and the second interior in communication, and a first filter which is in communication with a first interior of the first bag body. A first end of the communication pipe is capable of being connected to a dialysis circuit, and a second end thereof is disposed within the mixing region.
    Type: Application
    Filed: December 11, 2018
    Publication date: October 15, 2020
    Inventors: Hiroshi Nimura, Masato Fujiwara, Takayoshi Yokoyama
  • Patent number: 10773006
    Abstract: This dialysis-fluid supply system, which mixes a diluent and at least two drugs to generate a dialysis fluid, and outputs said dialysis fluid, is provided with: two tanks which mix the drugs and the diluent to generate the dialysis fluid, and store said dialysis fluid; a water supply device and a drug supply device which supply the diluent and the drugs to each of the tanks; mechanisms for outputting, to a dialysis device, the dialysis fluid stored in each of the tanks; and a control unit for controlling the driving of these. During output of the dialysis fluid from at least one of the tanks, the control unit sequentially switches the supply destination tank for the drugs and the diluent, and the dialysis-fluid output source tank, between the two tanks in order to generate the dialysis fluid in the other tank.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: September 15, 2020
    Assignee: NIKKISO CO., LTD.
    Inventors: Masato Fujiwara, Yoshimichi Masuda, Hiroshi Nimura
  • Publication number: 20200230311
    Abstract: A blood purification device used with a blood circuit includes an arterial-side line and a venous-side line attached to a blood purifier to which, at the ends thereof, the arterial-side line and the venous-side line are connected, the blood purification device including: a supply line connected to a supply unit which supplies a priming fluid, and which is capable of being connected to a leading end of the venous-side line; a discharge line connected to a discharge unit which discharges the priming fluid after use, and which is capable of being connected to a leading end of the arterial-side line; and a blood pump which is disposed upon the arterial-side line. By driving the blood pump in a state of the supply line being connected to the venous-side line and the discharge line being connected to the arterial-side line, the blood circuit and the blood purifier are primed.
    Type: Application
    Filed: August 7, 2017
    Publication date: July 23, 2020
    Applicant: NIKKISO CO., LTD.
    Inventors: Hiroshi NIMURA, Yoshimichi MASUDA, Masato FUJIWARA
  • Patent number: 10682451
    Abstract: Provided is a calibration method for flowmeters in a blood dialysis system, whereby highly accurate calibration can be performed even by omitting a reference flowmeter not directly relating to dialysis therapy. This calibration method comprises: while preventing outflow into a blood channel in a blood purifier, supplying a liquid to a channel, said channel passing through an inflow flowmeter and an outflow flowmeter; and then calibrating the inflow flowmeter and the outflow flowmeter correction whereby, at the time of liquid supply, a value measured by the outflow flowmeter is equalized to a value measured by inflow flowmeter.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 16, 2020
    Assignee: NIKKISO CO., LTD.
    Inventors: Yoshimichi Masuda, Masato Fujiwara, Hiroshi Nimura
  • Patent number: 10576197
    Abstract: A blood purification device for purifying blood drawn from a body and then returning the blood into the body, including: a pump provided midway along a fluid path through which blood or a dialysis fluid flows; a valve that is provided midway along the fluid path and closes or opens a part of the fluid path; and a control unit that causes a blood purification process of passing the blood or the dialysis fluid through the fluid path for blood purification, a priming process of driving the pump and the valve to supply a priming fluid to the fluid path before the blood purification processing, and a pressure reduction process of reducing pressure in a gap in the fluid path to a negative pressure state before supply of the priming fluid.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: March 3, 2020
    Assignee: NIKKISO CO., LTD.
    Inventors: Masato Fujiwara, Yoshimichi Masuda, Hiroshi Nimura, Yoichi Jimbo
  • Publication number: 20190184150
    Abstract: An adapter set that is attached to artery-side and vein-side shunt connectors-that are provided on a blood circuit. The adapter set includes: an artery-side adapter that has one end thereof connected to the artery-side shunt connector, has the other end thereof connected to a drainage port that is provided on the outside of the blood circuit, and thereby connects the artery-side shunt connector and the drainage port fluid tight; and a vein-side adapter that has one end thereof connected to the vein-side shunt connector, has the other end thereof connected to a supply port that is provided on the outside of the blood circuit, and thereby connects the vein-side shunt connector and the supply port fluid tight. The structure of the other end of the artery-side adapter and the structure of the other end of the vein-side adapter are different.
    Type: Application
    Filed: August 7, 2017
    Publication date: June 20, 2019
    Applicant: NIKKISO CO., LTD.
    Inventors: Hiroshi NIMURA, Yoshimichi MASUDA, Masato FUJIWARA
  • Publication number: 20190054225
    Abstract: This extracorporeal circulation cassette is provided with: a blood circuit (10) comprising a flexible tube and having a blood tube access portion set in a predetermined position in a device; a dialysate circuit (12) comprising a flexible tube and having a dialysate tube access portion set in a predetermined position in the device; a first panel (4) and a second panel (6) that are rigid and that integrate the blood circuit (10) and the dialysate circuit (12) while sandwiching the blood circuit (10) and the dialysate circuit (12) from both sides; and a window portion formed in a part of at least one of the first panel (4) and the second panel (6), disposed in a predetermined position in the device. The blood tube access portion and the dialysate tube access portion are positioned in the window portion.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 21, 2019
    Applicant: NIKKISO CO., LTD.
    Inventors: Hiroshi NIMURA, Yoshimichi MASUDA, Masato FUJIWARA
  • Patent number: 10124106
    Abstract: The blood purification apparatus has a control device (19) that performs a venous returning blood process S1, an arterial returning blood process S4 and a negative pressure applying process S1a. The returning of the blood is performed by substituting a physiological saline solution for the blood in the blood circuit. The negative pressure applying process S1a releases a negative pressure after applying the negative pressure to a flow route on an upstream side from an arrangement position of a blood pump 4 in the arterial blood circuit (1). The blood pump (4) is in a normal rotation and an electromagnetic valve V3 switches over the physiological saline solution supplying line 8 from a closing state to a circulating state.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: November 13, 2018
    Assignee: Nikkiso Company Limited
    Inventors: Hiroshi Nimura, Kazumi Yokoyama, Tomohiro Furuhashi
  • Publication number: 20180133385
    Abstract: Provided is a calibration method for flowmeters in a blood dialysis system, whereby highly accurate calibration can be performed even by omitting a reference flowmeter not directly relating to dialysis therapy. This calibration method comprises: while preventing outflow into a blood channel in a blood purifier, supplying a liquid to a channel, said channel passing through an inflow flowmeter and an outflow flowmeter; and then calibrating the inflow flowmeter and the outflow flowmeter correction whereby, at the time of liquid supply, a value measured by the outflow flowmeter is equalized to a value measured by inflow flowmeter.
    Type: Application
    Filed: April 11, 2016
    Publication date: May 17, 2018
    Applicant: NIKKISO CO., LTD.
    Inventors: Yoshimichi MASUDA, Masato FUJIWARA, Hiroshi NIMURA