Patents by Inventor Hiroshi Okuyama

Hiroshi Okuyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101532
    Abstract: A compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy is provided. The present inventors have conducted studies on a compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy, and confirmed that a heteroaryl carboxamide compound has DGK ? (DGKzeta) inhibitory effect, leading to completion of the present invention. The heteroaryl carboxamide compound of the present invention has DGK ? inhibitory effect, and can be used as a therapeutic agent for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 28, 2024
    Inventors: Hideyuki Watanabe, Takashi Kamikubo, Akio Kamikawa, Takuya Washio, Yohei Seki, Keiichiro Okuyama, Osamu Ikeda, Hiroshi Tomiyama, Yoshinori Iwai, Akihiko Nakamura, Kozo Miyasaka
  • Publication number: 20230398955
    Abstract: An in-vehicle use control system includes: a state management part which acquires the information on an operational state of the system; a memory storage part which memorizes the information on the operational state of the system, which is acquired by the state management part; a control part which has a plurality of control functions; a list management part which holds lists in which the correspondence relation between the control function of the control part and the normal operating state of the control function is defined; and a monitoring part which chooses the list held in the list management part, based on the operational state which is memorized in the memory storage part, compares the normal operating state of a control function which is defined in the list, and an execution state of the control part, and monitors whether the operation of the control function is normal or not.
    Type: Application
    Filed: November 24, 2020
    Publication date: December 14, 2023
    Applicant: Mitsubishi Electric Corporation
    Inventors: Kojiro CHIKAMATSU, Toshiki IKEGASHIRA, Hiroshi OKUYAMA
  • Publication number: 20230302701
    Abstract: There is provided a method for controlling a fluidity index of a molten resin, which can detect the fluidity of a molten resin even during successive molding operations and, in addition, can control the fluidity within a target range. The method includes: assuming that a narrow flow path, formed in a flow path for the molten resin, is a capillary or an orifice, and measuring, based on the amount of a metered molten resin and the back pressure applied to the screw during a metering step, a fluidity index which indicates the fluidity of the metered molten resin; and feeding back the measured fluidity index value and comparing it with a target value, and controlling the back pressure or the rotating speed of the screw so as to eliminate a deviation between the target value and the measured value.
    Type: Application
    Filed: October 21, 2020
    Publication date: September 28, 2023
    Applicant: SHIBAUR MACHINE CO., LTD.
    Inventor: Hiroshi OKUYAMA
  • Publication number: 20230069461
    Abstract: The in-vehicle control system in which a plurality of ECUs for controlling in-vehicle devices are connected to be able to communicate with each other is provided with an information set setting unit for setting an information set by combining information targeting different ECUs from among the original information relating to control functions of sound ECUs, an information collecting unit for collecting present information corresponding to the original information from each of the ECUs targeted by the information set, and an abnormality detection unit for detecting any one of the ECUs targeted to be abnormal when a degree of coincidence between correct answer information calculated by an evaluation function f with the information set as an argument and an evaluation value calculated by the evaluation function with the present information corresponding to the information set as an argument is lower than a criterion.
    Type: Application
    Filed: April 10, 2020
    Publication date: March 2, 2023
    Applicant: Mitsubishi Electric Corporation
    Inventor: Hiroshi OKUYAMA
  • Publication number: 20220242023
    Abstract: There is provided a molten resin fluidity index measuring method which can detect the fluidity of a molten resin online even during successive molding operations. The method includes: assuming that a narrow flow path, formed in a flow path for the molten resin, is a capillary or an orifice in a metering step in which the molten resin is collected in front of the screw; measuring, with an injection apparatus of the injection molding machine, the amount of the metered resin and the back pressure applied to the screw during the metering step; and calculating, based on the amount of the metered resin and the back pressure, a fluidity index which indicates the fluidity properties of the metered molten resin.
    Type: Application
    Filed: February 4, 2020
    Publication date: August 4, 2022
    Applicant: SHIBAURA MACHINE CO., LTD.
    Inventor: Hiroshi OKUYAMA
  • Patent number: 11126730
    Abstract: Provided is an inspection system capable of inspecting whether or not a control device mounted to a vehicle normally operates also during usage. An inspection information generation unit of a server generates security inspection information for use in inspection of a function of an ECU on the basis of ECU design information and security information, and the security inspection information is transmitted to an ECU_GW. In the ECU_GW having received the security inspection information, an ECU_GW control unit performs a conversion process, and transmits information obtained by the conversion process to an ECU_A and an ECU_B. When receiving the information, each of the ECU_A and the ECU_B determines, with use of a determination reference held in advance, whether the received information is normal or abnormal.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: September 21, 2021
    Assignee: Mitsubishi Electric Corporation
    Inventor: Hiroshi Okuyama
  • Patent number: 10978822
    Abstract: A connector is provided with a cable that includes a conductor and an insulation, connector bodies that are provided on one ends in an extending direction of the cable, and a cover unit that covers and integrates each of the one ends of the cable and each of the connector bodies. The cable includes a first cohesion unit provided on a surface of the insulation at each of one ends over an entire circumference around the extending direction of the cable, and fixed to the cover unit so as to be detachable by cohesive fracture.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: April 13, 2021
    Assignee: OMRON Corporation
    Inventors: Hirokazu Hoshino, Taijiro Fujiwara, Masato Matoba, Masaki Nakamura, Masaru Higuchi, Hiroshi Okuyama
  • Patent number: 10789365
    Abstract: A first processing environment includes: a control processing unit configured to execute control processing on a control subject; a first storage area for storing data for controlling the control subject; and a verification determination unit. A second processing environment includes: a second storage area for storing an expected value; a verification value generation unit; and a verification execution unit. The verification value generation unit generates the verification value before the control processing is stopped. The verification execution unit executes comparison processing of comparing the expected value and the verification value before the control processing is activated.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: September 29, 2020
    Assignee: Mitsubishi Electric Corporation
    Inventors: Toshiki Ikegashira, Toshinori Matsui, Koji Shimamura, Hiroshi Okuyama
  • Publication number: 20200176921
    Abstract: A connector is provided with a cable that includes a conductor and an insulation, connector bodies that are provided on one ends in an extending direction of the cable, and a cover unit that covers and integrates each of the one ends of the cable and each of the connector bodies. The cable includes a first cohesion unit provided on a surface of the insulation at each of one ends over an entire circumference around the extending direction of the cable, and fixed to the cover unit so as to be detachable by cohesive fracture.
    Type: Application
    Filed: November 2, 2018
    Publication date: June 4, 2020
    Applicant: OMRON Corporation
    Inventors: Hirokazu HOSHINO, Taijiro FUJIWARA, Masato MATOBA, Masaki NAKAMURA, Masaru HIGUCHI, Hiroshi OKUYAMA
  • Patent number: 10496393
    Abstract: A first control device includes a data processing controller that generates and transfers information indicating a current operating condition of the first control device and information indicating a current operating condition of a vehicle, and transfers a most recent version of a security program, to which the program is to be updated, to a second control device, while the second control device, having received the most recent version of the security program from the first control device, specifies the current operating condition of the vehicle on the basis of the information obtained from the first control device, and when the specified current operating condition matches a vehicle operating condition in which processing for updating the program to the most recent version of the security program is possible, executes processing for updating the program to the most recent version of the security program.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: December 3, 2019
    Assignee: Mitsubishi Electric Corporation
    Inventors: Hiroshi Okuyama, Toshinori Matsui, Hiroyuki Saito
  • Publication number: 20190340112
    Abstract: In a test device, a communication unit sequentially receives messages partially including a test target signal of a plurality of bits transmitted from an ECU. A judgment unit checks the value of the test target signal included in a message received by the communication unit in a first duration against a first expected value, checks the value of the test target signal included in a message received by the communication unit in a second duration different from the first duration against a second expected value acquired by inverting each bit of the first expected value, and judges a test on the ECU as pass or fail based on both of the check results.
    Type: Application
    Filed: January 25, 2017
    Publication date: November 7, 2019
    Applicant: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Madoka BABA, Hiroshi OKUYAMA
  • Publication number: 20190332778
    Abstract: Provided is an inspection system capable of inspecting whether or not a control device mounted to a vehicle normally operates also during usage. An inspection information generation unit of a server generates security inspection information for use in inspection of a function of an ECU on the basis of ECU design information and security information, and the security inspection information is transmitted to an ECU_GW. In the ECU_GW having received the security inspection information, an ECU_GW control unit performs a conversion process, and transmits information obtained by the conversion process to an ECU_A and an ECU_B. When receiving the information, each of the ECU_A and the ECU_B determines, with use of a determination reference held in advance, whether the received information is normal or abnormal.
    Type: Application
    Filed: January 22, 2019
    Publication date: October 31, 2019
    Applicant: Mitsubishi Electric Corporation
    Inventor: Hiroshi OKUYAMA
  • Publication number: 20190102557
    Abstract: A first processing environment includes: a control processing unit configured to execute control processing on a control subject; a first storage area for storing data for controlling the control subject; and a verification determination unit. A second processing environment includes: a second storage area for storing an expected value; a verification value generation unit; and a verification execution unit. The verification value generation unit generates the verification value before the control processing is stopped. The verification execution unit executes comparison processing of comparing the expected value and the verification value before the control processing is activated.
    Type: Application
    Filed: March 28, 2018
    Publication date: April 4, 2019
    Applicant: Mitsubishi Electric Corporation
    Inventors: Toshiki IKEGASHIRA, Toshinori MATSUI, Koji SHIMAMURA, Hiroshi OKUYAMA
  • Publication number: 20180136924
    Abstract: A first control device includes a data processing controller that generates and transfers information indicating a current operating condition of the first control device and information indicating a current operating condition of a vehicle, and transfers a most recent version of a security program, to which the program is to be updated, to a second control device, while the second control device, having received the most recent version of the security program from the first control device, specifies the current operating condition of the vehicle on the basis of the information obtained from the first control device, and when the specified current operating condition matches a vehicle operating condition in which processing for updating the program to the most recent version of the security program is possible, executes processing for updating the program to the most recent version of the security program.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 17, 2018
    Applicant: Mitsubishi Electric Corporation
    Inventors: Hiroshi OKUYAMA, Toshinori MATSUI, Hiroyuki SAITO
  • Patent number: 9493167
    Abstract: Before a communication control device ECU falls into a sleep state or a power-off state, a substitution request is transmitted to an ECU, among substitute candidate devices ECU to ECU, that is determined by a substitute transmission acceptability determining unit as being capable of taking over the communication control device. A substitution-capable processing load quantity, a substitution-capable process importance level, or a failure determination result of each of the ECUs is used as determination criteria when the substitute transmission acceptability determining unit of the ECU determines a substitute device, and the determination is carried out in an order that takes into consideration the process importance level of each of the ECUs during travelling or at a standstill, to prevent failures in a network or abnormal behaviors of a vehicle.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: November 15, 2016
    Assignee: Mitsubishi Electric Corporation
    Inventors: Hiroshi Okuyama, Toru Morita, Toshinori Matsui, Madoka Baba, Kiyohiro Morita
  • Publication number: 20150298626
    Abstract: Before a communication control device ECU falls into a sleep state or a power-off state, a substitution request is transmitted to an ECU, among substitute candidate devices ECU to ECU, that is determined by a substitute transmission acceptability determining unit as being capable of taking over the communication control device. A substitution-capable processing load quantity, a substitution-capable process importance level, or a failure determination result of each of the ECUs is used as determination criteria when the substitute transmission acceptability determining unit of the ECU determines a substitute device, and the determination is carried out in an order that takes into consideration the process importance level of each of the ECUs during travelling or at a standstill, to prevent failures in a network or abnormal behaviors of a vehicle.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 22, 2015
    Applicant: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Hiroshi OKUYAMA, Toru MORITA, Toshinori MATSUI, Madoka BABA, Kiyohiro MORITA
  • Patent number: 8716140
    Abstract: A micropattern is joined to a substrate (W1) by: a first group of covering step and micropattern forming step by etching in a transfer step; and a second group of covering step and micropattern forming step by etching in the transfer step.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: May 6, 2014
    Assignee: Toshiba Kikai Kabushiki Kaisha
    Inventors: Hiroshi Goto, Hiroshi Okuyama, Mitsunori Kokubo, Kentaro Ishibashi
  • Patent number: 8703618
    Abstract: A micropattern is joined to a substrate (W1) by: a first group of covering step and micropattern forming step by etching in a transfer step; and a second group of covering step and micropattern forming step by etching in the transfer step.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: April 22, 2014
    Assignee: Toshiba Kikai Kabushiki Kaisha
    Inventors: Hiroshi Goto, Hiroshi Okuyama, Mitsunori Kokubo, Kentaro Ishibashi
  • Patent number: 8685862
    Abstract: A micropattern is joined to a substrate (W1) by: a first group of covering step and micropattern forming step by etching in a transfer step; and a second group of covering step and micropattern forming step by etching in the transfer step.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: April 1, 2014
    Assignee: Toshiba Kikai Kabushiki Kaisha
    Inventors: Hiroshi Goto, Hiroshi Okuyama, Mitsunori Kokubo, Kentaro Ishibashi
  • Patent number: 8526162
    Abstract: A conducting portion includes a plurality of conducting inner electrodes. Each of a pair of capacitance portions includes a plurality of signal inner electrodes while adjacently opposing each other in the laminating direction, a plurality of first grounding inner electrodes while adjacently opposing each other in the laminating direction, and a plurality of second grounding inner electrodes while adjacently opposing each other in the laminating direction. The plurality of first grounding inner electrodes are located between the conducting portion and the plurality of signal inner electrodes, while one of the first grounding inner electrodes adjacently opposes one of the first signal inner electrodes in the laminating direction. The plurality of second grounding inner electrodes are located between principal faces opposing each other in the laminating direction in the outer surface and the plurality of signal inner electrodes.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: September 3, 2013
    Assignee: TDK Corporation
    Inventors: Masaaki Togashi, Takashi Aoki, Hiroshi Okuyama, Yutaro Kotani