Abstract: Circular dichroism can be accurately measured even when a phase modulation element with a distortion component is used. A circular dichroism measuring method using a circular dichroism measuring device 2 includes a step of measuring Ip(t) (S101: phase amount change acquisition step), a step of measuring Is(t) (S102: sample data acquisition step), a step of converting Ip(t) to ?(t) (S103: phase amount change acquisition step), a step of converting Is(t) to Is(?) (S104: analysis step/Is(?) calculation step), and a step of performing curve fitting to calculate matrix elements S00, S02, and S03 (S105: analysis step/matrix element calculation step).

Abstract: An optical measurement device includes a light source configured to output a terahertz wave and coaxial light having a wavelength different from the wavelength of the terahertz wave, coaxially with the terahertz wave; an intensity modulation unit configured to perform intensity modulation of at least the terahertz wave of the terahertz wave and the coaxial light in a predetermined modulation frequency; and a light detection unit configured to synchronously detects each of the terahertz wave and the coaxial light which have acted on a measurement subject via the intensity modulation unit based on the modulation frequency.

Abstract: Circular dichroism can be accurately measured even when a phase modulation element with a distortion component is used. A circular dichroism measuring method using a circular dichroism measuring device 2 includes a step of measuring Ip(t) (S101: phase amount change acquisition step), a step of measuring Is(t) (S102: sample data acquisition step), a step of converting Ip(t) to ?(t) (S103: phase amount change acquisition step), a step of converting Is(t) to Is(?) (S104: analysis step/Is(?) calculation step), and a step of performing curve fitting to calculate matrix elements S00, S02, and S03 (S105: analysis step/matrix element calculation step).

Abstract: The present invention relates to a method for detecting an amyloid ? oligomer which includes a test sample and thioflavin T are brought into contact with each other, fluorescence of the thioflavin T is measured to obtain time-resolved fluorescence spectra, the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 are respectively normalized to obtain normalized spectra (t1<t2?t3 <t4), and determination is made to confirm the presence or absence of an amyloid ? oligomer in the test sample on the basis of the two normalized spectra, and shifting of the normalized spectrum of time period t3 to t4 towards the low wavelength side in comparison to the normalized spectrum of time period t1 to t2 indicates the presence of an amyloid ? oligomer in the test sample.

Abstract: The present invention relates to a method for purifying pure thioflavin T having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent and a step of carrying out liquid-liquid extraction of the thioflavin T solution with a non-polar solvent.

Abstract: The present invention relates to a method for purifying pure thioflavin T in having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent, a step of bringing the thioflavin T solution into contact with a non-polar polymeric porous body, and a step of separating the thioflavin T solution after the contact from the non-polar polymeric porous body.

Abstract: Circular dichroism can be accurately measured even when a phase modulation element with a distortion component is used. A circular dichroism measuring method using a circular dichroism measuring device 2 includes a step of measuring Ip(t) (S101: phase amount change acquisition step), a step of measuring Is(t) (S102: sample data acquisition step), a step of converting Ip(t) to ?(t) (S103: phase amount change acquisition step), a step of converting Is(t) to Is(?) (S104: analysis step/Is(?) calculation step), and a step of performing curve fitting to calculate matrix elements S00, S02, and S03 (S105: analysis step/matrix element calculation step).

Abstract: An object of the present invention is to appropriately and easily evaluate a photosynthetic function of a photosynthetic sample contained in an evaluation sample. An evaluation method for photosynthetic sample according to the present invention is for evaluating a state of a photosynthetic sample with a photosynthetic function based on temporal data of a luminescence amount of delayed luminescence emitted from the photosynthetic sample. First, characteristic values that indicate characteristics are determined for a plurality of time periods in the temporal data. An evaluation value is then computed by weighting the characteristic values. The state of the photosynthetic sample is then evaluated based on the evaluation value.

Abstract: An object of the present invention is to appropriately and easily evaluate a photosynthetic function of a photosynthetic sample contained in an evaluation sample. An evaluation method for photosynthetic sample according to the present invention is for evaluating a state of a photosynthetic sample with a photosynthetic function based on temporal data of a luminescence amount of delayed luminescence emitted from the photosynthetic sample. First, characteristic values that indicate characteristics are determined for a plurality of time periods in the temporal data. An evaluation value is then computed by weighting the characteristic values. The state of the photosynthetic sample is then evaluated based on the evaluation value.

Abstract: In a method for finely pulverizing an organic compound 5 in treatment target liquid 2 to manufacture fine particles of the organic compound 5, a laser beam having a wavelength which is longer than the light absorption band of the organic compound 5 or corresponds to an absorption wavelength of solvent is irradiated to the treatment target liquid 2 to finely pulverize the organic compound 5, thereby manufacturing fine particles of the organic compound 5. According to this manufacturing method, the fine particles can be manufactured with sufficiently preventing photochemical reactions of the organic compound 5 in the treatment target liquid 2. Accordingly, a fine particle manufacturing method and apparatus that can manufacture fine particles while sufficiently preventing photochemical reactions in the organic compound, fine particles, and injectable agent and a manufacturing method for the injectable agent can be implemented.

Abstract: The present invention relates to an isothiocyanated cyclodextrin derivative which can label various kinds of organic compounds containing an amino group as their functional group. In some embodiments, the derivative can be a cyclodextrin derivative in which at least one primary hydroxyl group is substituted by an isothiocyanato group and expressed by the compound expressed by formula (I), ##STR1## wherein n is an integer from 5 to 7.