Patents by Inventor Hiroshi Shiigi

Hiroshi Shiigi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240151721
    Abstract: A label corresponding to each of various bacteria and virus species is prepared, and a detector for detecting bacteria and/or virus in a sample to be tested is provided based on the attribute of the label. DPV detector includes an electrode chip, a voltage applying unit for applying a voltage in a predetermined range to the electrode chip, a current measuring unit for measuring a peak current value outputted from the electrode chip in accordance with the applied voltage, a data memory unit for storing in advance the peak current value and the applied voltage value at the time of the peak current for each of the plurality of types of metal nanostructures, a target specifying unit for comparing the measured data and the accumulated data of the current measuring unit to specify a target coupled to the metal nanostructure, and a displaying unit for displaying the specified target.
    Type: Application
    Filed: December 27, 2021
    Publication date: May 9, 2024
    Applicant: UNIVERSITY PUBLIC CORPORATION OSAKA
    Inventor: Hiroshi SHIIGI
  • Publication number: 20230303806
    Abstract: The present invention provides a composite film that has electrical conductivity, mechanical strength and flexibility which resist being affected by moisture and are stable, and that can prevent position aberration and peeling in the case where the composite film is used in close contact with a body to be contacted; a sensor element, a body fat percentage measuring device, and an electrochemical cell device which are provided with the composite film; and a wearable measuring device including the sensor element. The composite film includes electroconductive nanoparticles and nanofibers, wherein the nanofibers have a plurality of gaps therebetween that are communicated with an outside; the electroconductive nanoparticles adhere to the surface of the nanofibers and exist in the plurality of gaps; the nanofibers are hydrophilic and biocompatible; and the composite film is electroconductive and is used in close contact with a body to be contacted that is hydrophilic-treated or that contains moisture.
    Type: Application
    Filed: July 30, 2021
    Publication date: September 28, 2023
    Applicant: UNIVERSITY PUBLIC CORPORATION OSAKA
    Inventor: Hiroshi SHIIGI
  • Patent number: 9797842
    Abstract: Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: October 24, 2017
    Assignee: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION
    Inventors: Shiho Tokonami, Takuya Iida, Yojiro Yamamoto, Hiroshi Shiigi, Tsutomu Nagaoka
  • Publication number: 20160018391
    Abstract: The present invention is a sensor for detecting a microorganism, which is provided with a detection unit equipped with a detection electrode and a polymer layer, wherein the polymer layer is arranged on the detection electrode and is provided with a template having a three-dimensional structure complementary to a three-dimensional structure of a microorganism to be detected. The sensor detects a microorganism on the basis of the captured state of the microorganism onto the template. The polymer layer is formed by a manufacturing method including a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected to form a polymer layer having the microorganism incorporated therein on the detection electrode, and a disruption step of bringing at least a part of the microorganism incorporated in the polymer layer into contact with a solution containing a lytic enzyme to disrupt the microorganism.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Applicants: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, Sharp Kabushiki Kaisha
    Inventors: Mugihei IKEMIZU, Shiho TOKONAMI, Hiroshi SHIIGI, Tsutomu NAGAOKA
  • Patent number: 9206461
    Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: December 8, 2015
    Assignees: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION, SHARP KABUSHIKI KAISHA
    Inventors: Shiho Tokonami, Hiroshi Shiigi, Tsutomu Nagaoka, Mugihei Ikemizu, Mari Takahashi
  • Publication number: 20130337498
    Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.
    Type: Application
    Filed: March 6, 2012
    Publication date: December 19, 2013
    Applicants: SHARP KABUSHIKI KAISHA, OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION
    Inventors: Shiho Tokonami, Hiroshi Shiigi, Tsutomu Nagaoka, Mugihei Ikemizu, Mari Takahashi
  • Publication number: 20130252275
    Abstract: Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.
    Type: Application
    Filed: December 8, 2011
    Publication date: September 26, 2013
    Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION
    Inventors: Shiho Tokonami, Takuya Iida, Yojiro Yamamoto, Hiroshi Shiigi, Tsutomu Nagaoka