Patents by Inventor Hiroshi Shimoda

Hiroshi Shimoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190854
    Abstract: A method of reducing muscle damage in a human being includes providing an extract of Kenyan purple tea (scientific name: Camellia sinensis; variety name: TRFK306) containing 1,2-di-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl-?-D-glucose (GHG). Then, an effective amount of the purple tea extract is administered to a body of a human being engaged in intensive exercise to reduce muscle damage associated with the intensive exercise.
    Type: Application
    Filed: February 9, 2023
    Publication date: June 22, 2023
    Inventors: Hiroshi SHIMODA, Hiromichi MURAI
  • Publication number: 20220370539
    Abstract: A 5?-reductase inhibitor contains saw palmetto extract and seaberry extract as an active ingredient in a synergistic compounding ratio, wherein the compounding ratio by weight of the saw palmetto extract and the seaberry extract is 3:1˜2. The 5?-reductase inhibitor containing the saw palmetto extract and seaberry extract or just the seaberry extract as a 5?-reductase inhibitor can be administered to the human body in order to inhibit 5?-reductase. The 5?-reductase inhibitor is useful as a prostate enlargement inhibitor, an androgenic alopecia inhibitor, and an acne prevention and amelioration agent. The 5?-reductase inhibitor can be part of a food or drink composition or a cosmetic composition.
    Type: Application
    Filed: May 1, 2020
    Publication date: November 24, 2022
    Inventors: Kenchi MIYASAKA, Norihito SHIMIZU, Hiroshi SHIMODA, Hiromichi MURAI
  • Patent number: 11478495
    Abstract: An AMP-activated protein kinase (AMPK) activating agent comprises 1,2-di-O-galloyl-4,6-O—(S)-hexahydroxydiphenoyl-b-D-glucose (“GHG”) as an active ingredient. The AMPK activating agent can be a GHG-containing composition wherein the GHG is an active ingredient of the composition. The GHG-containing composition can be derived from Kenyan purple tea, whose scientific name is Camellia sinensis, variety name: TRFK306. An effective amount of the GHG can be administered to a cell to activate the AMPK. Drinks, foods, and cosmetics can have the GHG as an active ingredient.
    Type: Grant
    Filed: November 10, 2019
    Date of Patent: October 25, 2022
    Assignee: ORYZA OIL & FAT CHEMICAL CO., LTD.
    Inventors: Toru Takarada, Hiroshi Shimoda, Hiromichi Murai
  • Publication number: 20210268011
    Abstract: An AMP-activated protein kinase (AMPK) activating agent comprises 1,2-di-O-galloyl-4,6-O—(S)-hexahydroxydiphenoyl-b-D-glucose (“GHG”) as an active ingredient. The AMPK activating agent can be a GHG-containing composition wherein the GHG is an active ingredient of the composition. The GHG-containing composition can be derived from Kenyan purple tea, whose scientific name is Camellia sinensis, variety name: TRFK306. An effective amount of the GHG can be administered to a cell to activate the AMPK. Drinks, foods, and cosmetics can have the GHG as an active ingredient.
    Type: Application
    Filed: November 10, 2019
    Publication date: September 2, 2021
    Inventors: Toru TAKARADA, Hiroshi SHIMODA, Hiromichi MURAl
  • Publication number: 20210228673
    Abstract: A method of promoting NO-production in a human being includes providing an extract of Kenyan purple tea (scientific name: Camellia sinensis; variety name: TRFK306) containing 1,2-di-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl-?-D-glucose (GHG). Then, an effective amount of the purple tea extract is administered to a body of a human being in need of NO-production promotion.
    Type: Application
    Filed: January 7, 2021
    Publication date: July 29, 2021
    Inventors: Hiroshi SHIMODA, Hiromichi MURAI
  • Patent number: 11033566
    Abstract: This invention provides a prophylactic and therapeutic agent for dry eye, having new ingredients to reduce the deterioration of the lacrimal secretory ability and to inhibit the generation of radical oxygen in lacrimal gland tissue. The prophylactic and therapeutic agent for dry eye of this invention contains the maqui berry extract as the active substance of this invention, i.e. containing delphinidin glycoside extracted from the maqui berry and at least one or more of the active substances delphinidin-3-sambubioside-5-glucoside, delphinidin-3,5-diglucoside, delphinidin-3-sambubioside and delphinidin-3-glucoside, preferably delphinidin-3,5-diglucoside.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: June 15, 2021
    Assignees: ORYZA OIL & FAT CHEMICAL CO., LTD., KEIO UNIVERSITY
    Inventors: Kazuo Tsubota, Shigeru Nakamura, Toshihiro Imada, Junji Tanaka, Takashi Kadekaru, Hiroshi Shimoda, Hiromichi Murai
  • Publication number: 20200360338
    Abstract: A method for activating energy metabolism in muscle cells by administering to human beings at least one active substance comprising methoxyflavone for energy metabolism activation, the at least one active substance shown in the following Chemical Formula 1, wherein for Chemical Formula 1, R1 means an alkyl group with the number of carbons being 1 and R2 is hydrogen, and neither the B-ring nor the C-ring of the flavone skeleton has a substituent The active substance can be part of a composition of food.
    Type: Application
    Filed: July 29, 2020
    Publication date: November 19, 2020
    Inventors: Kazuya TODA, Shogo TAKEDA, Hiroshi SHIMODA, Hiromichi MURAI
  • Patent number: 10837002
    Abstract: The present disclosure relates to: an artificial peritoneal tissue comprising a cellular tissue and a mesothelial cell layer that covers the surface of the cellular tissue, wherein the cellular tissue comprises a fibroblast, an extracellular matrix, and a vascular endothelial cell and/or a lymphatic endothelial cell each capable of forming a lumen; and a method for producing the artificial peritoneal tissue.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: November 17, 2020
    Assignees: HIROSAKI UNIVERSITY, OSAKA UNIVERSITY
    Inventors: Hiroshi Shimoda, Yoshiya Asano, Mitsuru Akashi, Michiya Matsusaki
  • Publication number: 20200263894
    Abstract: An air environment control system includes one or more adjustment devices that adjust an air environment in a space; and a control device that controls the one or more adjustment devices. The air environment control device includes an air environment control unit that controls (i) at least one of the one or more adjustment devices to create a cooler environment in the space, when a person does intellectual work in the space; and (ii) at least one of the one or more adjustment devices to create a warmer environment warmer than the cooler environment in the space, when the person has a break in the space. The control unit further controls at least one of the one or more adjustment devices to apply cool stimulation to the person, when the person starts the intellectual work in the space.
    Type: Application
    Filed: April 19, 2018
    Publication date: August 20, 2020
    Inventors: Fumiaki OOBAYASHI, Kazuhiro TANIGUCHI, Hiroshi SHIMODA, Hirotake ISHII, Kimi UEDA, Kosuke SUGITA, Shogo OGATA, Shota SHIMONAKA
  • Publication number: 20200143308
    Abstract: An intellectual productivity evaluation device includes: an obtainment unit configured to obtain a set of answer times required by a subject to accomplish a task of answering a plurality of questions, the task being imposed on the subject as intellectual work; an evaluation unit configured to calculate an evaluation value related to a depth of concentration of the subject in a concentrated state using the set of answer times obtained by the obtainment unit based on a model in which the subject is in the concentrated state or an unconcentrated state during the intellectual work; and an output unit configured to output evaluation value information indicating the evaluation value calculated by the evaluation unit.
    Type: Application
    Filed: April 20, 2018
    Publication date: May 7, 2020
    Inventors: Fumiaki OOBAYASHI, Hiroshi SHIMODA, Hirotake ISHII, Shota SHIMONAKA, Kimi UEDA
  • Publication number: 20200037416
    Abstract: Provided is an environment control system that controls an environment of a space in which a user performs an intellectual task. The environment control system includes: a controller which performs scene control for reproducing one or more predetermined scenes in the space by controlling one or more luminaires that emit illumination light that illuminates a predetermined area in the space and one or more air conditioning devices that air-condition the space. The one or more predetermined scenes include: a concentration scene that causes the user to concentrate on the intellectual task; and a rest scene that eases the concentration of the user. The controller switches between concentration scene control for reproducing the concentration scene and rest scene control for reproducing the rest scene when a predetermined condition is satisfied.
    Type: Application
    Filed: February 27, 2017
    Publication date: January 30, 2020
    Inventors: Fumiaki OOBAYASHI, Kazuhiro TANIGUCHI, Hiroshi SHIMODA, Hirotake ISHII, Shota SHIMONAKA, Kosuke SUGITA, Kimi UEDA, Yuta TSUJI
  • Publication number: 20190343858
    Abstract: This invention provides a new application to 1,2-di-O-galloyl-4,6-O—(S)-hexahydroxydiphenoyl-ß-D-glucose (i.e. GHG) that is contained in Kenyan purple tea (scientific name: Camellia sinensis; variety name: TRFK306), as well as a new circadian-rhythm regulator that can be widely used in medicines, foods and drinks, and cosmetics. The circadian-rhythm regulator of this invention is characterized in containing the GHG as an active ingredient for promoting the BMAL1 gene-expression. Also, the circadian-rhythm regulator of this invention is characterized in containing the GHG-content extract derived from Kenyan purple tea as an active ingredient for promoting the BMAL1 gene-expression.
    Type: Application
    Filed: January 30, 2017
    Publication date: November 14, 2019
    Inventors: Hiroshi SHIMODA, Marina KOHATSU, Kazuya TODA, Hiromichi MURAI
  • Publication number: 20190328701
    Abstract: A method for activating metabolism for muscle cells involves administering an energy-metabolic activating agent to a human patient, the energy-metabolic activing agent as follows: (1) a sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from the following: 5-hydroxy-3,7-dimethoxyflavone; techtochrysin; 3,7,4?-trimethylkaempferol; retusine; pentamethyiquercetin; trimethylapigenin; tetramethylkaempferol; and 5, 7-dimethoxyflavone, (2) a sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from either techtochrysin or 5,7-dimethoxyflavone, and (3) a sugar transporter (GLUT4) gene-expression promoting agent within the muscle cells that includes any one of the chemical compounds shown in the following chemical formula 1. (Of such formula 1, R1 and R2, respectively, mean an alkyl group with hydrogen or with 1˜3-carbon.
    Type: Application
    Filed: July 8, 2019
    Publication date: October 31, 2019
    Inventors: Kazuya TODA, Shogo TAKEDA, Hiroshi SHIMODA, Hiromichi MURAI
  • Publication number: 20190268999
    Abstract: Provided is an environment control system that controls an environment of a space. The environment control system includes: a controller that performs scene control for reproducing one or more predetermined scenes in the space. The controller includes: a lighting controller that adjusts an illuminance or a color temperature of illumination light that is emitted by one or more luminaires and illuminates a predetermined area in the space, by controlling the one or more luminaires; and an air conditioning controller that adjusts a temperature, a humidity, and an airflow in the space by controlling one or more air conditioning devices that air-condition the space. The controller performs the scene control by adjusting the illuminance or the temperature of the illumination light, and the temperature, the humidity, and the airflow in the space.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 29, 2019
    Inventors: Fumiaki OOBAYASHI, Kazuhiro TANIGUCHI, Isamu NISHIZAWA, Hiroshi SHIMODA, Hirotake ISHII, Shota SHIMONAKA, Kosuke SUGITA, Kimi UEDA, Yuta TSUJI
  • Patent number: 10019690
    Abstract: An intellectual-productivity analysis apparatus includes a presentation device, an input device, and an evaluation device. The presentation device presents a plurality of questions to a test subject. The input device allows the test subject input an answer to each question. The evaluation device includes a work memory part and an evaluating arithmetic part. The work memory part stores the answering time from a time when a question is presented on the presentation device to a time when the answer is inputted into the input device for each of the plurality of questions. The evaluating arithmetic part calculates an evaluation value on the intellectual productivity of the test subject during a measurement period of measuring the answering time of each of the plurality of questions by extracting a feature amount from the set of the answering time stored in the work memory part.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: July 10, 2018
    Assignee: Panasonic Intellectual Property Management Co., Ltd.
    Inventors: Fumiaki Oobayashi, Mikio Iwakawa, Hiroshi Shimoda, Hirotake Ishii, Kazune Miyagi, Kotaro Oishi, Shutaro Kunimasa, Kosuke Uchiyama, Kyoichi Seo
  • Publication number: 20180117000
    Abstract: This invention provides a new energy-metabolic activating agent for muscle cells and provides compounds that are widely used in foods and drinks and in medicines and in quasi-drugs or the like. The technical features of this invention are as follows: (1) A sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from the following: 5-hydroxy-3,7-dimethoxyflavone; techtochrysin; 3,7,4?-trimethylkaempferol; retusine; pentamethylquercetin; trimethylapigenin; tetramethylkaempferol; and 5,7-dimethoxyflavone, (2) A sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from either techtochrysin or 5,7-dimethoxyflavone, and (3) A sugar transporter (GLUT4) gene-expression promoting agent within the muscle cells that includes any one of the chemical compounds shown in the following chemical formula 1. (Of such formula 1, R1 and R2, respectively, mean an alkyl group with hydrogen or with 1˜3-carbon.
    Type: Application
    Filed: March 24, 2016
    Publication date: May 3, 2018
    Inventors: Kazuya TODA, Shogo TAKEDA, Hiroshi SHIMODA, Hiromichi MURAI
  • Patent number: D941446
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: January 18, 2022
    Assignee: TOTO Ltd.
    Inventors: Masafumi Ishikawa, Hiroshi Shimoda, Chikahiro Kakimoto
  • Patent number: D952110
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: May 17, 2022
    Assignee: TOTO Ltd.
    Inventors: Kazuki Otsuka, Masanobu Wano, Hiroshi Shimoda
  • Patent number: D954919
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: June 14, 2022
    Assignee: TOTO Ltd.
    Inventors: Kazuki Otsuka, Hiroshi Shimoda
  • Patent number: D999349
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: September 19, 2023
    Assignee: TOTO Ltd.
    Inventors: Kazuki Otsuka, Hiroshi Shimoda