Patents by Inventor Hiroshi Suemizu

Hiroshi Suemizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-HUMAN VERTEBRATE COMPRISING HUMAN LIVER CELLS TRANSPLANTED THEREIN AND METHOD FOR PRODUCING THE SAME
    Publication number: 20210251199
    Abstract: This invention provides a non-human vertebrate exhibiting a higher human liver cell growth rate, a higher human liver cell replacement rate, and higher histological-physiological human reproducibility than existing non-human vertebrates comprising the human liver transplanted therein and a method for producing such non-human vertebrate. Specifically, the method for producing a transgenic non-human vertebrate comprising human liver cells transplanted therein comprises transplanting human liver cells in a non-human vertebrate that has impaired or lowered immune reactions against humans in the presence of human IL-6 in vivo.
    Type: Application
    Filed: December 12, 2019
    Publication date: August 19, 2021
    Applicant: Central Institute for Experimental Animals
    Inventor: Hiroshi SUEMIZU
  • Gene markers of tumor metastasis
    Publication number: 20070092881
    Abstract: The invention concerns the study of tumor metastasis in a NOD/SCID/?cnull transgenic mouse model and the identification of tumor markers, including markers of tumors with high metastatic potential, using information obtained in this mouse model.
    Type: Application
    Filed: September 29, 2004
    Publication date: April 26, 2007
    Applicants: CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS, CHUGAI PHARMACEUTICAL, INC., CENTER FOR THE ADVANCEMENT OF HEALTH AND BIOSCIENCE, USA
    Inventors: Yasuyuki Ohnishi, Masato Nakamura, Hiroshi Suemizu, Makoto Monnai
  • Establishment of human cancer cell lines with metastatic potential using NOD/SCID
    Publication number: 20050249666
    Abstract: The invention provides a new reproducible transgenic mouse model for the study of tumor metastasis. In particular, the invention concerns the study of tumor metastasis in a NOD/SCID/?cnull transgenic mouse model.
    Type: Application
    Filed: September 29, 2004
    Publication date: November 10, 2005
    Applicants: CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS, CENTER FOR THE ADVANCEMENT OF HEALTH AND BIOSCIENCE, USA
    Inventors: Masato Nakamura, Yasuyuki Ohnishi, Hiroshi Suemizu, Makoto Monnai