Patents by Inventor Hiroshi Sumichika

Hiroshi Sumichika has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amide derivatives and medicinal use thereof
    Patent number: 8198454
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: June 12, 2012
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh
  • Amide derivatives and medicinal use thereof
    Patent number: 7855297
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: December 21, 2010
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh
  • Novel amide derivatives and medicinal use thereof
    Publication number: 20100041656
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the like].
    Type: Application
    Filed: June 30, 2009
    Publication date: February 18, 2010
    Inventors: Mitsubaru NAKAMURA, Takao KAMAHORI, Seigo ISHIBUCHI, Yoichi NAKA, Hiroshi SUMICHIKA, Katsuhiko ITOH
  • Optically Active Tetrahydronaphthalene Derivative
    Publication number: 20080194640
    Abstract: A compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate thereof or a solvate thereof, which shows not only a C5a receptor antagonistic activity but also high activity in the biological availability, as compared to its racemate.
    Type: Application
    Filed: February 7, 2006
    Publication date: August 14, 2008
    Inventors: Mitsuharu Nakamura, Seigo Ishibuchi, Tatsuyuki Ohtsuka, Hiroshi Sumichika, Sumie Sekiguchi, Takayuki Ishige, Naoko Ueda
  • 3-substituted urea derivatives and medicinal use thereof
    Patent number: 7105567
    Abstract: The present invention relates to a urea derivative of the formula (1) wherein each symbol is as described in the specification, a pharmaceutically acceptable salt thereof and pharmaceutical use thereof. The compound of the present invention has a C5a receptor antagonistic action and is useful as an agent for the prophylaxis or treatment of diseases or syndromes due to inflammation caused by C5a [e.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis, pancreatitis and the like) due to activation of leukocytes caused by ischemia, trauma, burn, surgical invasion and the like].
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: September 12, 2006
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Seigo Ishibuchi, Hiroshi Sumichika, Katsuhiko Itoh, Yoichi Naka
  • Novel amide derivatives and medicinal use thereof ugs
    Publication number: 20040138223
    Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action 1
    Type: Application
    Filed: May 8, 2003
    Publication date: July 15, 2004
    Inventors: Mitsuharu Nakamura, Takao Kamahori, Seigo Ishibuchi, Yoichi Naka, Hiroshi Sumichika, Katsuhiko Itoh
  • Novel 3-substituted urea derivatives and medicinal use thereof
    Publication number: 20030207939
    Abstract: The present invention relates to a urea derivative of the formula (1) 1
    Type: Application
    Filed: February 5, 2003
    Publication date: November 6, 2003
    Inventors: Seigo Ishibuchi, Hiroshi Sumichika, Katsuhiko Itoh, Yoichi Naka