Abstract: In one form, a direction changing device is provided including: a first mounting section; and a second mounting section, wherein an axial direction of the first mounting section and an axial direction of the second mounting section intersect each other or are parallel to each other in plan view, and in a condition where a catheter or a sheath introducer in which the catheter is inserted is mounted to the first mounting section and the second mounting section, the catheter or the sheath introducer adopts a curved shape such that a catheter or sheath introducer portion mounted to the first mounting section extends proximally to distally in one direction and a catheter or sheath introducer portion mounted to the second mounting section extends proximally to distally in another direction with the directions being different from each other.

Abstract: A stimulus-responsive gel material includes: a polymeric material containing as constituent components, a first monomer having a chemical structure represented by the following formula (1) and a second monomer having higher hydrophobicity than the first monomer; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein the wavelength of a reflected light from the material changes according to the concentration of salt to come in contact with the material. In the formula (1), R is a substituent containing at least a carbon atom and a hydrogen atom, and when the number of carbon atoms in R is denoted by n and the number of oxygen atoms in R is denoted by m, n-m is an integer of 3 or more.

Abstract: A housing tool suppresses rotation of a tubular body in a winding direction that holds an elongated medical body in a packaging body, and suppresses deformation of a distal end portion of the elongated medical body. The housing tool includes a tube-shaped holder that is wound in a circular shape for holding a guide wire, a fastening member that fixes adjacent portions of the wound holder, and a mounting member that includes engagement portions and to be engaged with the fastening member, reaches an outer side of a circle of the holder wound in a circular shape, and covers an end portion of the holder from which the guide wire is derived.

Abstract: To provide an authentication device capable of performing authentication accurately even when biological information changes with time. An authentication device (1) includes an acquisition unit (2) configured to acquire biological information about a user; an authentication processing unit (4); a storage unit (6) configured to store standard biological information and basic biological information; and a standard biological information updating unit (8). When a difference between the standard biological information and current biological information is less than a first threshold, the authentication processing unit (4) determines that authentication is established. When the authentication is established by the authentication processing unit (4), the standard biological information updating unit (8) updates the standard biological information according to the current biological information for which the authentication is established, based on the basic biological information and a second threshold.

Abstract: A sweat collection device as a fluid collection device includes a collection section which collects sweat, and a discharge section which discharges the sweat collected by the collection section from the collection section. Further, the sweat collection device is attached to the skin as an adherend, and the collection section is configured to be hermetically sealed by attaching the sweat collection device to the skin. Further, the sweat collection device includes a transfer section which connects the collection section and the discharge section to each other. Further, the sweat collection device includes a gel-like response section which is placed on any of the collection section, the transfer section, and the discharge section, and responds to lactic acid contained in sweat.

Abstract: Provided herein are methods or making and using whole or partial organ ECM structures comprising an anticoagulant. Also provided are organ structures prepared according to those methods.

Abstract: A culture container includes a gel section constituted by a material containing a stimulus-responsive gel which expands or contracts in response to a stimulus by a given substance in at least a portion of a part coming into contact with a culture solution.

Abstract: A stimulus-responsive gel material includes: a first polymer containing an OH group and having a network structure; a second polymer having a phenylboronic acid structure; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein a polymer chain of the second polymer penetrates into the network of the first polymer.

Abstract: A sensor includes a gel for a sensor and an electrode. The gel for a sensor includes a stimulus-responsive gel, first particles which are contained in the stimulus-responsive gel and are constituted by a material containing an electrically conductive substance, and second particles which are contained in the stimulus-responsive gel and contribute to structural coloration. It is preferred that when the electrical resistivity of the electrically conductive substance is represented by R1 (?·m) and the electrical resistivity of the constituent material of the second particles is represented by R2 (?·m), the following relationship is satisfied: 1×1012?R2/R1?1×1023. It is preferred that when the refractive index of the constituent material of the first particles is represented by n1 and the refractive index of the constituent material of the second particles is represented by n2, the following relationship is satisfied: ?0.8?n2?n1?1.5.

Abstract: A sensor includes a stimulus-responsive gel which reversibly expands or contracts in response to a given stimulus, an electrically conductive gel containing electrically conductive particles constituted by a material containing an electrically conductive substance, and an electrode connected to the electrically conductive gel. The electrically conductive particles preferably have an average particle diameter of 10 nm or more and 1000 ?m or less.

Abstract: A hemostatic device includes a flexible band adapted to be wrapped around a patient's limb at a site on the limb where bleeding is to be stopped, a portion for securing the band in a wrapped state to the limb, a curved plate which is made of a material more rigid than the band and at least a portion of which is curved toward the inner peripheral side thereof, a main balloon which is provided on the inner peripheral side of the curved plate and which inflates when a fluid is introduced therein, and a pressing member which is provided between the curved plate and the main balloon so that at least a portion thereof overlaps with the balloon and which is adapted for pressing against the balloon. The device provides an excellent hemostatic effect and prevents numbness and poor circulation in areas peripheral to the site of attachment.

Abstract: A puncture device is provided that does not allow an outer needle to collapse or rise at the time of puncture and exhibits small puncture resistance. A puncture device 1 includes: a hollow outer needle 2; an outer needle hub 3 provided at a proximal end portion of the outer needle 2; a hollow inner needle 4 inserted into the outer needle 2 for use; and an inner needle hub 5 provided at a proximal end portion of the inner needle 4. The inner needle 4 includes, from the distal side, a sharp needlepoint 41, a small diameter portion 42 having an almost uniform outer diameter; an intermediate portion 43 formed as a tapered portion which is progressively increased in outer diameter as it goes toward the proximal end; and a larger diameter portion 44 having inner and outer diameters larger than inner and outer diameters, respectively, of the small diameter portion 42.

Abstract: A stimulus-responsive gel material includes: a first polymer having an OH group; a second polymer having a phenylboronic acid structure; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein the material is capable of being put into a first state in which the OH group of the first polymer and the phenylboronic acid structure of the second polymer are bonded to each other, and a second state in which the bond between the OH group of the first polymer and the phenylboronic acid structure of the second polymer is dissociated, and the wavelength of a reflected light from the material is different between the first state and the second state.

Abstract: A gel sensor includes a first region constituted by a material containing a stimulus-responsive gel and a second region containing fine particles at a higher content than the first region. It is preferred that the first region does not contain the fine particles. The gel sensor has the first region provided on the upstream side of the second region in the moving direction of a specimen, and when the area of the face of the first region on the upstream side is represented by S1 (mm2) and the area of the face of the second region on the side facing the first region is represented by S2 (mm2), it is preferred to satisfy the following relation: S2?S1.

Abstract: One aspect of the invention provides a method for harvesting adult cells from an organ. The method includes perfusing the organ with a perfusate and isolating adult cells from the organ, thereby harvesting the adult cells from the organ. Another aspect of the invention provides a method for rehabilitating an organ. The method includes: dividing the organ into a first portion and a second portion, perfusing the first portion with a decellularization medium, isolating adult cells from the second portion, and recellularizing the first portion with a suspension of the adult cells, thereby rehabilitating the organ.

Abstract: A medical tube which is relatively thin in thickness over its entirety while an outer layer and an inner layer are preferably prevented from being separated from each other. A medical tube includes a first layer and a second layer that is provided adjacent to an inner circumferential surface of the first layer. The medical tube also includes a wedge-shaped convex portion that is provided on an outer circumferential surface of the second layer so as to be widened in width radially outward, and a concave portion that is provided on an inner circumferential surface of the first layer, with the convex portion and the concave portion engaging each other.

Abstract: A stimulus-responsive gel material includes: a first polymer having an OH group; a second polymer having a phenylboronic acid structure; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein the material is capable of being put into a first state in which the OH group of the first polymer and the phenylboronic acid structure of the second polymer are bonded to each other, and a second state in which the bond between the OH group of the first polymer and the phenylboronic acid structure of the second polymer is dissociated, and the wavelength of a reflected light from the material is different between the first state and the second state.

Abstract: A stimulus-responsive gel material includes: a first polymer containing an OH group and having a network structure; a second polymer having a phenylboronic acid structure; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein a polymer chain of the second polymer penetrates into the network of the first polymer.

Abstract: A stimulus-responsive gel material includes: a polymeric material containing as constituent components, a first monomer having a chemical structure represented by the following formula (1) and a second monomer having higher hydrophobicity than the first monomer; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein the wavelength of a reflected light from the material changes according to the concentration of salt to come in contact with the material. In the formula (1), R is a substituent containing at least a carbon atom and a hydrogen atom, and when the number of carbon atoms in R is denoted by n and the number of oxygen atoms in R is denoted by m, n-m is an integer of 3 or more.

Abstract: An LED lamp provides a strong red color with a natural appearance. The LED lamp is provided with an LED module and a filter. The LED module includes a blue LED with a main emission peak in the 440 nm to 460 nm wavelength band, a green/yellow phosphor that is excited by light emitted by the blue LED, and a red phosphor that is excited by light emitted by at least one of the blue LED and the green/yellow phosphor. The filter reduces the spectral radiation intensity of at least a portion of the 570 nm to 590 nm wavelength band among light emitted by the LED module.