Patents by Inventor Hirotaka Kumagai

Hirotaka Kumagai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITION FOR TESTING, PREVENTING, AND TREATING ASPERGILLUS FUMIGATUS INFECTION
    Publication number: 20140242085
    Abstract: As a result of the analysis by an SST-REX method so as to identify a target molecule for treating and testing an Aspergillus fumigatus infection, a YMAF1 protein has been found out, which is mainly localized in the cell wall of Aspergillus fumigatus. Moreover, it has been found out that YMAF1 protein-deficient Aspergillus fumigatus has reduced spore-forming ability and pathogenicity. Further, it has been found out that the survival rate of experimental mice having aspergillosis (invasive Aspergillus model mice) is improved by preparing and administering an antibody against the YMAF1 protein. Furthermore, it has been found out that Aspergillus fumigatus can be detected with a favorable sensitivity by an ELISA system using the antibody.
    Type: Application
    Filed: August 12, 2011
    Publication date: August 28, 2014
    Applicants: MEDICAL & BIOLOGICAL LABORATORIES CO., LTD., NATIONAL INSTITUTE OF INFECTIOUS DISEASES
    Inventors: Yoshitsugu Miyazaki, Satoshi Yamagoe, Masunori Kajikawa, Masahito Sugiura, Reiko Itoh, Hirotaka Kumagai