Abstract: Provided is PCV2 VLP that can be used as a vaccine for use in the field of animal husbandry and that has high molecular stability against physicochemical load. A fusion protein according to the present invention includes a capsid protein of porcine circovirus type 2 and an immunoglobulin-binding domain.

Abstract: The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).

Abstract: A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.

Abstract: The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).

Abstract: A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.

Abstract: A method for increasing the amount of trans-1,4-polyisoprene contained in a plant, and a method for effectively producing trans-1,4-polyisoprene using a plant are provided. A long-chain trans-prenyl diphosphate synthase gene that comprises DNA having at least one base sequence selected from the group consisting of a base sequence from positions 88 to 1134 of the base sequence of SEQ ID NO: 1 or a complementary sequence thereof, a base sequence from positions 42 to 1088 of the base sequence of SEQ ID NO: 3 or a complementary sequence thereof, and a base sequence from positions 91 to 1140 of the base sequence of SEQ ID NO: 5 or a complementary sequence thereof are disclosed; as well as a plant transformed with an expression vector containing the gene.

Abstract: A method for increasing the amount of trans-1,4-polyisoprene contained in a plant, and a method for effectively producing trans-1,4-polyisoprene using a plant are provided. A long-chain trans-prenyl diphosphate synthase gene that comprises DNA having at least one base sequence selected from the group consisting of a base sequence from positions 88 to 1134 of the base sequence of SEQ ID NO: 1 or a complementary sequence thereof, a base sequence from positions 42 to 1088 of the base sequence of SEQ D NO: 3 or a complementary sequence thereof, and a base sequence from positions 91 to 1140 of the base sequence of SEQ ID NO: 5 or a complementary sequence thereof are disclosed; as well as a plant transformed with an expression vector containing the gene.

Abstract: In the biosynthetic reaction system of caffeine, enzymes which catalyze these reactions respectively, and a method of composite utilization of genes encoding these enzymes, respectively are provided. A process for producing 7-methylxanthine, theobromine or caffeine which comprises methylation of xanthosine, ribose removal of 7-methylxanthosine, methylation of 7-methylxanthine, and/or methylation of theobromine ex vivo, in the presence of a combination of two or more of the enzymes a, c and d, and the cellular extract b.