Abstract: The DC/DC converter is provided with a failure detector that detects a failure in at least one of a first output-side voltage sensor, a second output-side voltage sensor, and an input-side voltage sensor, based on the respective detection values of the input-side voltage sensor, the first output-side voltage sensor, the second output-side voltage sensor, and a DC power source voltage sensor.

Abstract: The DC/DC converter is provided with a failure detector that detects a failure in at least one of a first output-side voltage sensor, a second output-side voltage sensor, and an input-side voltage sensor, based on the respective detection values of the input-side voltage sensor, the first output-side voltage sensor, the second output-side voltage sensor, and a DC power source voltage sensor.

Abstract: A method for separating a vesicle having a lipid bilayer membrane from a biological sample, includes forming a complex of a vesicle and a solid phase carrier by bringing the biological sample containing the vesicle having the lipid bilayer membrane into contact with the solid phase carrier to which a ligand for recognizing a surface antigen present on a surface of the vesicle is bound. The complex is washed. The forming is performed in the presence of a nonionic surfactant which does not comprise an aromatic group to reduce an aggregation of the complex.

Abstract: Provided is a method capable of reducing non-specific adsorption onto a solid phase carrier, and capable of selectively and efficiently separating a vesicle having a lipid bilayer membrane. A method of separating a vesicle having a lipid bilayer membrane includes: a complex forming step of forming a complex of a vesicle having a lipid bilayer membrane and a solid phase carrier to which a ligand which recognizes a surface antigen present on a surface of the vesicle is bound, by bringing a biological sample containing the vesicle into contact with the solid phase carrier; and a washing step of washing the complex, in which at least any one of the complex forming step and the washing step is performed under an environment having a salt concentration of from 0.15 M to 2 M.

Abstract: To provide a method for separating a vesicle having a lipid bilayer membrane, which has excellent efficiency of removing impurities and is unsuch asly to cause disruption of the vesicle having a lipid bilayer membrane. A method for separating the vesicle having the lipid bilayer membrane including: a complex forming step for forming a complex of the vesicle and the solid phase carrier by bringing a biological sample including a vesicle having a lipid bilayer membrane into contact with a solid phase carrier to which a ligand for recognizing a surface antigen present on a surface of the vesicle and is bound, a washing step for washing the complex, wherein at least any of the complex forming step and the washing step is performed in the presence of a nonionic surfactant.

Abstract: The present invention provides a therapeutic or prophylactic agent for systemic inflammatory response syndrome (SIRS), which contains a polypeptide comprising an amino acid sequence the same or substantially the same as the amino acid sequence of the N-terminal domain of pentraxin 3 capable of binding to histone to form a polypeptide aggregate, or a pharmacologically acceptable salt thereof. The present invention also provides a reagent for quantification and a quantification method of histone, which utilize the polypeptide or a pharmacologically acceptable salt thereof. Furthermore, the present invention provides a polypeptide aggregate containing the polypeptide or a pharmacologically acceptable salt thereof and histone and a production method thereof.

Abstract: A wedge-shaped digital clock wirelessly receives weather, traffic, and other information over the Internet for display along with the time of day. The clock is wedge-shaped so that it can rest in two orientations, one with the display tilted back slightly from vertical and one with the display substantially horizontal. An accelerometer can signal the orientation to an internal processor, which can flip the text on the display as appropriate for the user flipping or turning the housing upside down, for example.

Abstract: A wedge-shaped digital clock wirelessly receives weather, traffic, and other information over the Internet for display along with the time of day. The clock is wedge-shaped so that it can rest in two orientations, one with the display tilted back slightly from vertical and one with the display substantially horizontal. An accelerometer can signal the orientation to an internal processor, which can flip the text on the display as appropriate for the user flipping or turning the housing upside down, for example.

Abstract: A wedge-shaped digital clock wirelessly receives weather, traffic, and other information over the Internet for display along with the time of day. The clock is wedge-shaped so that it can rest in two orientations, one with the display tilted back slightly from vertical and one with the display substantially horizontal. An accelerometer can signal the orientation to an internal processor, which can flip the text on the display as appropriate for the user flipping or turning the housing upside down, for example.

Abstract: The present invention provides a mutant firefly luciferase consisting of a mutant amino acid sequence derived from the amino acid sequence of a wild-type firefly luciferase by at least substitution (a), (b), or (c) below and having luminescence intensity higher than that of the wild-type firefly luciferase.