Abstract: An object to be achieved by the present invention is to provide a technique for enhancing the anticancer effect of ubenimex; in particular, enhancing its anticancer effect on solid cancer. This object can be achieved by a compound containing a chain structure in which a plurality of ubenimex molecules is linked to a chain polymer.

Abstract: The laser device includes a laser crystal, a resonator including a pair of mirrors between which the laser crystal is interposed, a Q switch that is disposed on an optical path of the resonator and controls a Q value of the resonator, and a Brewster thin-film polarizer that is disposed on the optical path of the resonator and transmits selectively p-polarized light. The thin-film polarizer has wavelength selectivity in which a p-polarized light transmittance at a first wavelength exhibiting a maximum gain of the laser crystal is 5% or more to 25% or less, the p-polarized light transmittance monotonically increases as a wavelength becomes longer than the first wavelength, and a maximum transmittance is exhibited at a third wavelength. The laser device oscillates laser light at a second wavelength that is a wavelength longer than the first wavelength and shorter than or equal to the third wavelength.

Abstract: A photoacoustic apparatus includes a laser light irradiating unit that irradiates an inside of a subject with pulsed light; a photoacoustic signal acquiring unit that acquires a photoacoustic signal from a photoacoustic wave from the subject; a light amount detecting unit that detects a light amount of the pulsed light; a correlation data memory that stores first correlation data and second correlation data; an energy estimating unit that estimates an energy on the basis of the amount of the pulsed light and the first correlation data; a pulse width estimating unit that estimates a pulse width on the basis of the estimated energy and the second correlation data; and a photoacoustic signal correcting unit that corrects the photoacoustic signal on the basis of a first difference between the estimated energy and a reference energy and a second difference between the estimated pulse width and a reference pulse width.

Abstract: A solid-state laser device includes a resonator composed of a pair of mirrors, a laser rod disposed in the resonator, and a laser chamber. The resonator and the laser rod are disposed in a housing. The laser rod is inserted through a hole of the laser chamber and is supported in a state in which two end portions are exposed. An O-ring is disposed at an exposed root of at least one rod end portion exposed from the laser chamber. The solid-state laser device includes a cover member that is disposed on a rod side surface of the rod end portion between the O-ring and a rod end surface and that blocks incidence of stray light, which is generated in the housing, on the O-ring.

Abstract: A solid-state laser device includes a laser rod made of an alexandrite crystal; a flash lamp that outputs excitation light for exciting the laser rod, a glass tube for a lamp being made of quartz glass that at least blocks deep ultraviolet light having a wavelength of 200 nm to 300 nm, and transmits visible light having a wavelength of 400 nm or more; and a laser chamber that contains a tubular reflector that includes a hole part containing at least a portion of the laser rod or a portion of the flash lamp and is made of a porous material of polytetrafluoroethylene, an inner wall surface of the hole part being as a reflecting surface that reflects the excitation light.

Abstract: A diode rectifier rectifies an AC voltage output from a neutral-grounding three-phase AC power supply to a DC voltage. A smoothing capacitor smoothes the DC voltage rectified by the diode rectifier. An inverter converts the DC voltage smoothed by the smoothing capacitor into a desired AC voltage. A bidirectional switch and a Y capacitor are connected in series between one end of the smoothing capacitor and the ground. A detector detects a voltage across both ends of the smoothing capacitor. A controller drives the bidirectional switch in response to an output of the detector.

Abstract: Provided is a solid-state laser device in which a linear resonator including an output mirror and a rear mirror, a laser rod, and optical members are provided on a common base and are contained in a housing having the base as a portion. A holding part is provided to hold an excitation light source that extends parallel to the laser rod on a side of the laser rod opposite to the base. The optical members including a Q-switch are disposed between the laser rod and the rear mirror. An upper end position of the output mirror is at a position lower than a lower end position of the excitation light source held by the holding part, with the base as a reference. The holding part holds the excitation light source so as to be capable of being inserted and extracted with respect to the output mirror side in a longitudinal direction of the excitation light source.

Abstract: The present invention provides a titanosilicate separation membrane which can also be used for separating a mixed gas containing a molecule having a relatively small size, has high durability in a high temperature environment, and has a high permeation rate and a high selectivity for a mixed gas containing water vapor. A titanosilicate separation membrane has a CHA-type titanosilicate crystal structure formed on a porous support, wherein aluminum is not substantially contained in the backbone of the titanosilicate crystal structure, and the titanosilicate crystal structure is constituted by silicon, oxygen, and titanium.

Abstract: In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

Abstract: A solid-state laser device includes a resonator composed of a pair of mirrors, a laser rod disposed in the resonator, and a laser chamber. The resonator and the laser rod are disposed in a housing. The laser rod is inserted through a hole of the laser chamber and is supported in a state in which two end portions are exposed. An O-ring is disposed at an exposed root of at least one rod end portion exposed from the laser chamber. The solid-state laser device includes a cover member that is disposed on a rod side surface of the rod end portion between the O-ring and a rod end surface and that blocks incidence of stray light, which is generated in the housing, on the O-ring.

Abstract: A solid-state laser device includes a resonator composed of a pair of mirrors; a laser rod disposed in the resonator, the laser rod including an antireflection film on an end surface thereof and having a chamfered portion at a peripheral edge of the end surface; and an end-surface protection member that is disposed at a position facing the end surface of the laser rod, that has an opening defining portion that forms an opening whose diameter is smaller than a diameter of an outer periphery of the end surface, and that limits a laser light path region in the end surface of the laser rod to a region inside of the outer periphery of the end surface.

Abstract: A solid-state laser device includes a laser rod made of an alexandrite crystal; a flash lamp that outputs excitation light for exciting the laser rod, a glass tube for a lamp being made of quartz glass that at least blocks deep ultraviolet light having a wavelength of 200 nm to 300 nm, and transmits visible light having a wavelength of 400 nm or more; and a laser chamber that contains a tubular reflector that includes a hole part containing at least a portion of the laser rod or a portion of the flash lamp and is made of a porous material of polytetrafluoroethylene, an inner wall surface of the hole part being as a reflecting surface that reflects the excitation light.

Abstract: Provided is a solid-state laser device in which a linear resonator including an output mirror and a rear mirror, a laser rod, and optical members are provided on a common base and are contained in a housing having the base as a portion. A holding part is provided to hold an excitation light source that extends parallel to the laser rod on a side of the laser rod opposite to the base. The optical members including a Q-switch are disposed between the laser rod and the rear mirror. An upper end position of the output mirror is at a position lower than a lower end position of the excitation light source held by the holding part, with the base as a reference. The holding part holds the excitation light source so as to be capable of being inserted and extracted with respect to the output mirror side in a longitudinal direction of the excitation light source.

Abstract: Disclosed are a laser device which uses alexandrite crystal and is capable of suppressing abnormal oscillation even if the size thereof is reduced and suppressing damage to an AR coating on a Q switch or alexandrite crystal, and a photoacoustic measurement device. A laser rod 11 includes alexandrite crystal. A flash lamp 12 irradiates the laser rod 11 with excitation light. A resonator includes a pair of mirrors 14 and 15 with the laser rod 11 sandwiched therebetween. A Q switch 16 is inserted into the optical path of the resonator and controls the Q value of the resonator. A polarizer 17 is inserted into the resonator and is a non-coated Brewster polarizer which selectively transmits light in a predetermined polarization direction among light emitted from the laser rod.

Abstract: In a laser device that emits pulsed laser light by emitting excitation light to a laser medium in a state in which a first voltage is applied to a Q switch and changing the voltage applied to the Q switch from a first voltage to a second voltage after the emission of the excitation light, the application start timing of the first voltage during a normal operation is set to a timing at which the intensity of the pulsed laser light periodically changing due to the vibration of the Q switch is maximized.

Abstract: A Q switch is vibrated by applying a first voltage, and pulsed laser light is emitted by applying a second voltage to the Q switch at a point in time at which a preset delay time has passed from the start of emission of excitation light. Then, in this case, a time which is within a period, for which the vibration of the Q switch continues, and at which the intensity of the pulsed laser light periodically changing due to the vibration of the Q switch is maximized in a case where a point in time of application of the second voltage to the Q switch is changed is set as the delay time.

Abstract: In a solid-state laser device and a photoacoustic measurement device including the solid-state laser device, the distance between a laser rod and a flash lamp is narrowed. A shielding lid shields mirrors and an optical path of laser light from the outside. A first portion of a frame body of a laser chamber is exposed from the shielding lid. A flash lamp stored in the frame body of the laser chamber is able to be removed from and inserted into the first portion of the frame body. A thin film portion having a thickness smaller than the thickness of other portions of the shielding lid is provided in at least a part of a region of the shielding lid covering the optical path of a light beam on the outside in a longitudinal direction from the first portion of the frame body of the laser chamber.

Abstract: Disclosed are a laser device which uses alexandrite crystal and is capable of suppressing abnormal oscillation even if the size thereof is reduced and suppressing damage to an AR coating on a Q switch or alexandrite crystal, and a photoacoustic measurement device. A laser rod 11 includes alexandrite crystal. A flash lamp 12 irradiates the laser rod 11 with excitation light. A resonator includes a pair of mirrors 14 and 15 with the laser rod 11 sandwiched therebetween. A Q switch 16 is inserted into the optical path of the resonator and controls the Q value of the resonator. A polarizer 17 is inserted into the resonator and is a non-coated Brewster polarizer which selectively transmits light in a predetermined polarization direction among light emitted from the laser rod.

Abstract: A semiconductor integrated circuit includes: a plurality of current sources including a first transistor individually connected to a power source line and a bias line; and a plurality of bias blocks including a second transistor configured to constitute a current mirror circuit together with the first transistor, and to divide a reference current to be a reference of the current sources so that the reference current flows through the bias line.

Abstract: A radiation imaging apparatus includes a differential phase image producing section, a phase unwrapping section, a statistical operation section, and a correction processing section. The differential phase image producing section produces a differential phase image in which pixel values are wrapped into a predetermined range ?. The phase unwrapping section performs a phase unwrapping process to the differential phase image. The statistical operation section obtains a mode from statistical operation of pixel values in each subregion segmented in the unwrapped differential phase image. Each subregion is a unit in which error caused by the phase unwrapping process is to be corrected. The correction processing section calculates, for each pixel, an integer “n” which allows a difference ? between the mode and a pixel value of each pixel to satisfy n???/2??<n?+?/2, and subtracts n·? from each pixel value.