Patents by Inventor Hiroyasu Tobe

Hiroyasu Tobe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition for treating osteoporosis
    Patent number: 5679716
    Abstract: A therapeutic agent for osteoporosis comprising as an active ingredient xanthohumol. Xanthohumol obtained from hop extracts has a bone resorption inhibiting activity and is useful as a therapeutic agent for osteoporosis.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: October 21, 1997
    Assignee: Hoechst Japan Limited
    Inventors: Hiroyasu Tobe, Kazuyuki Kitamura, Osamu Komiyama
  • Treating osteoporosis with humulones
    Patent number: 5604263
    Abstract: A pharmaceutical composition for treating osteoporosis which comprises as an active ingredient an effective amount of one or more compounds selected from the-group comprising humulone, cohumulone, adhumulone, isohumulone, isocohumulone and isoadhumulone in combination with a pharmaceutically acceptable carrier or excipient. Humulone, cohumulone, adhumulone are the compounds belonging to .alpha. acids which are an ingredient extracted from hops, whilst isohumulone, isocohumulone and isoadhumulone are the compounds belonging to iso .alpha. acid derivatives which are isomers of .alpha. acids.The above described compounds have a bone resorption inhibiting activity and are useful for treating osteoporosis.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: February 18, 1997
    Assignee: Hoechst Japan Limited
    Inventors: Hiroyasu Tobe, Kazuyuki Kitamura
  • Process for producing daunomycin
    Patent number: 4592999
    Abstract: This invention is to provide a new microbial process for producing daunomycin by a mutant strain belonging to the genus Streptomyces.
    Type: Grant
    Filed: July 18, 1983
    Date of Patent: June 3, 1986
    Assignee: Sanraku Incorporated
    Inventors: Hamao Umezawa, Tomio Takeuchi, Kageaki Kouno, Tomoyuki Ishikura, Akihiro Yoshimoto, Yukio Takatsuki, Hiroyasu Tobe
  • Anthracycline antibiotics
    Patent number: 4474945
    Abstract: New anthracycline compounds, 2-hydroxyaclacinomycin B having potent antitumor activity and lower toxicity, and a process for producing 2-hydroxyaclacinomycins A, B, and N by fermentation.
    Type: Grant
    Filed: August 6, 1982
    Date of Patent: October 2, 1984
    Assignee: Sanraku-Ocean Co., Ltd.
    Inventors: Akihiro Yoshimoto, Hiroyasu Tobe, Tomoyuki Ishikura, Hamao Umezawa, Tomio Takeuchi