Abstract: An exchange capable of, when a failure occurs, preventing a service from deteriorating without requiring an operation performed by a user is provided. An exchange (1) includes a notification control unit (2) configured to, when the exchange enters an operating state, request a server apparatus to transmit a notification for making a predetermined application installed in a communication terminal registered in the server apparatus register the application in the exchange, and a terminal control unit (3) configured to register the predetermined application in the exchange.

Abstract: An exchange capable of, when a failure occurs, preventing a service from deteriorating without requiring an operation performed by a user is provided. An exchange (1) includes a notification control unit (2) configured to, when the exchange enters an operating state, request a server apparatus to transmit a notification for making a predetermined application installed in a communication terminal registered in the server apparatus register the application in the exchange, and a terminal control unit (3) configured to register the predetermined application in the exchange.

Abstract: Novel inhibitors of the enzyme action of lipoxygenase, especially 5-lipoxygenase and 12-lipoxygenase that are derived from the extraction of the seeds of the perilla (crispa) or perilla (frutescens) plant. These inhibitors are suitably extracted from these seeds using alcohol, preferably ethanol, to form an extract or more preferably to further extract the alcoholic extract with ethyl acetate and water to partition the active inhibitors to the ethyl acetate. The particularly preferred inhibitors are luteolin and chrysoeriol.