Abstract: Novel HIF inhibitors having low cytotoxicity and suitable for ophthalmologic treatment and agents for the treatment or prevention of ischemic diseases, glaucoma, optic nerve diseases, retinal degenerative diseases, retinal degenerative diseases, angiogenic retinal diseases, cancer, neurodegenerative or autoimmune diseases are provided. The present invention is a therapeutic or prophylactic agent for ischemic disease, glaucoma, optic nerve disease, retinal degenerative disease, retinal degenerative disease, angiogenic retinal disease, cancer, neurodegenerative disease, or autoimmune disease, which comprises as an active ingredient one or more or an extract thereof selected from the group consisting of plants belonging to the genus Asian, plants belonging to the genus Swiss, plants belonging to the genus Grape, plants belonging to the genus Brassica, fish belonging to the genus Kivinago, and so on.

Abstract: The heating cooker includes: a heating compartment having a bottom tray mounted at the bottom part; a light source provided on the upper side of the heating compartment; a light-receiving element for receiving light transmitted by the bottom tray out of the light emitted from the light source, the light-receiving element being provided on the lower side of the bottom tray; and a determining part for determining, on the basis of a light-reception signal detected by the light-receiving element, the presence/absence or the size of a heating object placed on the bottom tray in the heating compartment. Thus, a heating cooker capable of preventing leakage of steam and detecting the presence/absence of food in the heating compartment, even when heat cooking using steam is performed, is provided.

Abstract: The heating cooker includes: a heating compartment having a bottom tray mounted at the bottom part; a light source provided on the upper side of the heating compartment; a light-receiving element for receiving light transmitted by the bottom tray out of the light emitted from the light source, the light-receiving element being provided on the lower side of the bottom tray; and a determining part for determining, on the basis of a light-reception signal detected by the light-receiving element, the presence/absence or the size of a heating object placed on the bottom tray in the heating compartment. Thus, a heating cooker capable of preventing leakage of steam and detecting the presence/absence of food in the heating compartment, even when heat cooking using steam is performed, is provided.

Abstract: A fixing device includes a heat assembly including an endless belt, a heat source, an attachment member having an attachment surface and first and second side surfaces, and a slide sheet having first and second end portions that are respectively fixed to a first fixing portion at the first side surface and a second fixing portion at the second side surface, the slide sheet having a larger length from the first end portion to the second end portion than a length of a path of the attachment member extending from the first fixing portion to the second fixing portion through the first side surface, the attachment surface, and the second side surface; and a pressure roller that presses the outer surface of the endless belt to the attachment surface.

Abstract: The present invention provides: a novel metalloprotein, i.e., selenium-lactoferrin; and a process for producing the metalloprotein. Selenium-lactoferrin according to the present invention can be produced suitably by adding a selenium salt to a solution containing lactoferrin and/or apolactoferrin and then subjecting the resultant mixed solution to dialysis or ultrafiltration. Selenium-lactoferrin according to the present invention has an excellent therapeutic effect on corneal and conjunctival diseases, and is suitable for mass production on an industrial scale.

Abstract: A fixing device includes a heat assembly including an endless belt, a heat source, an attachment member having an attachment surface and first and second side surfaces, and a slide sheet having first and second end portions that are respectively fixed to a first fixing portion at the first side surface and a second fixing portion at the second side surface, the slide sheet having a larger length from the first end portion to the second end portion than a length of a path of the attachment member extending from the first fixing portion to the second fixing portion through the first side surface, the attachment surface, and the second side surface; and a pressure roller that presses the outer surface of the endless belt to the attachment surface.

Abstract: A fixing device includes a heat assembly including an endless belt, a heat source, an attachment member having an attachment surface and first and second side surfaces, and a slide sheet having first and second end portions that are respectively fixed to a first fixing portion at the first side surface and a second fixing portion at the second side surface, the slide sheet having a larger length from the first end portion to the second end portion than a length of a path of the attachment member extending from the first fixing portion to the second fixing portion through the first side surface, the attachment surface, and the second side surface; and a pressure roller that presses the outer surface of the endless belt to the attachment surface.

Abstract: A plastic optical fiber (POF) is provided which includes a core layer constructed such that a portion at least a certain distance away from a core center, as seen in cross section, contains a plurality of regions of polymer materials having different refractive indices, wherein the average refractive index per circumference continuously decreases with the increase in distance from the core center and wherein the refractive indices are discontinuously distributed on each whole circumference at each distance from the core center.

Abstract: An object detecting apparatus that detects an object including a magnetic body including: a detection signal acquiring unit that acquires a detection signal based on a magnetic signal; a disturbance source detection signal storage unit that stores a detection signal of a disturbance source that generates a disturbance component with respect to the detection signal; a determining unit that determines whether the detection signal acquired by the detection signal acquiring unit contains the disturbance component; an amplitude correction unit that corrects an amplitude of the disturbance source detection signal and generates an amplitude-corrected disturbance source detection signal; a disturbance component suppression unit that generates a determination signal by suppressing the disturbance component contained in the detection signal; and an object determination unit that determines whether the object is the object to be detected based on the determination signal.

Abstract: A baggage management gate including an exciting coil, a detecting coil and signal processing unit. The exciting coil forms an alternating magnetic field in a passage to an area from which manages objects to be carried in or carried out. The detecting coil detects a variation in the alternating magnetic field when magnetization of a magnetic material showing a large Barkhausen effect is reversed in the alternating magnetic field. The signal processing unit determines as to whether the magnetization reversal occurs in the alternating magnetic field due to the large Barkhausen effect or not, based on a signal detected by the detecting coil. The signal processing unit includes amplifier that amplifies the signal detected by the detecting coil with plural different amplification factors and output the amplified signals with each of the plural different amplification factors.

Abstract: A flat detector includes a first flat member and a second flat member both made of a nonmagnetic nonmetal, a first conductive wiring that generates an alternating magnetic field, the first conductive wiring being disposed on a surface of the first flat member facing toward the second flat member, a first layer made of a nonmagnetic metal and disposed at least on a surface of the first flat member, a second conductive wiring that detects a signal generated by magnetization reversal of a magnetic material, the magnetization reversal being caused by the alternating magnetic field generated by the first conductive wiring, the second conductive wiring being disposed on a surface of the second flat member facing toward the first flat member, and a second layer made of a nonmagnetic metal and disposed at least on a surface of the second flat member.

Abstract: A baggage management gate includes a first reading device and a second reading device, a detecting device, a determining unit, a first opening and closing device and a second opening and closing device. The baggage management gate manages baggage that is restricted to be carried in or out from a predetermined region. And in order away from the region in which the baggage is managed, the first reading device, the second opening and closing device, the detecting device for both the first person and the second person, the first opening and closing device, and the second reading device are arranged in an entrance direction from the passage to the management region in which the baggage is managed.

Abstract: The object of the present invention is to provide an adsorbent having an excellent AGEs adsorption ability. The present invention provides an adsorbent for advanced glycation end products consists of a copolymer resin having hydrophilic methacrylate, wherein the constituent unit of said copolymer resin consists of a particular methacrylate compounds and vinyl compounds. Preferably, the copolymer resin having hydrophilic methacrylate has one or more basic ion-exchange groups.

Abstract: An object detecting apparatus that detects an object including a magnetic body including: a detection signal acquiring unit that acquires a detection signal based on a magnetic signal; a disturbance source detection signal storage unit that stores a detection signal of a disturbance source that generates a disturbance component with respect to the detection signal; a determining unit that determines whether the detection signal acquired by the detection signal acquiring unit contains the disturbance component; an amplitude correction unit that corrects an amplitude of the disturbance source detection signal and generates an amplitude-corrected disturbance source detection signal; a disturbance component suppression unit that generates a determination signal by suppressing the disturbance component contained in the detection signal; and an object determination unit that determines whether the object is the object to be detected based on the determination signal.

Abstract: a flat detector includes a first flat member and a second flat member both made of a nonmagnetic nonmetal, a first conductive wiring that generates an alternating magnetic field, the first conductive wing being disposed on a surface of the first flat member facing toward the second flat member, a first layer made of a nonmagnetic metal and disposed at least on a surface of the first flat member, a second conductive wiring that detects a signal generated by magnetization reversal of a magnetic material, the magnetization reversal being caused by the alternating magnetic field generated by the first conductive wiring, the second conductive wiring being disposed on a surface of the second flat member facing toward the first flat member, and a second layer made of a nonmagnetic metal and disposed at least on a surface of the second flat member.

Abstract: A method and an apparatus for producing an apoprotein with which the apoprotein can be efficiently produced from a protein associated with cofactors such as metal ions. The method includes the step of adding an acid to a solution which contains a holoprotein, which is associated with a cofactor which is to be released under acidic conditions, and concentrating the solution with an ultrafiltration membrane. Accordingly, an apoprotein, which has released its cofactor, is produced, and the released cofactor is removed through the membrane along with the acid without reassociating with the apoprotein.

Abstract: The object of the present invention is to provide an adsorbent having an excellent AGEs adsorption ability. The present invention provides an adsorbent for advanced glycation end products consists of a copolymer resin having hydrophilic methacrylate, wherein the constituent unit of said copolymer resin consists of a particular methacrylate compounds and vinyl compounds. Preferably, the copolymer resin having hydrophilic methacrylate has one or more basic ion-exchange groups.

Abstract: An image forming apparatus includes an image reading unit that reads an image formed on a recording medium; a copy-prohibited medium detecting unit that detects whether a recording medium is a copy-prohibited medium; and a controller that controls to disable or inhibit copying of an image formed on a recording medium, when it is detected by the copy-prohibited medium detecting unit that the recording medium is the copy-prohibited medium, before the image on the recording medium is read by the image reading unit.

Abstract: A baggage management gate including an exciting coil, a detecting coil and signal processing unit. The exciting coil forms an alternating magnetic field in a passage to an area from which manages objects to be carried in or carried out. The detecting coil detects a variation in the alternating magnetic field when magnetization of a magnetic material showing a large Barkhausen effect is reversed in the alternating magnetic field. The signal processing unit determines as to whether the magnetization reversal occurs in the alternating magnetic field due to the large Barkhausen effect or not, based on a signal detected by the detecting coil. The signal processing unit includes amplifier that amplifies the signal detected by the detecting coil with plural different amplification factors and output the amplified signals with each of the plural different amplification factors.

Abstract: A control gate includes an exciting coil and a detecting coil. The exciting coil forms an alternating magnetic field in a passageway at an entrance to or an exit from an area where taking out or bringing in of an object is controlled. The detecting coil detects a change of the magnetic field when magnetic substance contained in the object generating a large Barkhausen effect causes magnetic inversion in the alternating magnetic field. The exciting coil is provided above the passageway and has a winding wire wound along a horizontal plane. The detecting coil is provided in a side part of the passageway and has a winding wire wound along a vertical plane which is parallel to a passing direction of the passageway.