Abstract: Disclosed is: a fluorescent dye comprising a compound, a tautomer of the compound, or a salt of the compound or the tautomer; a labeled composite substance comprising the fluorescent dye and a composite substance which are bonded to each other; a composition containing the fluorescent dye or the labeled composite substance; and a method for acquiring information about a substance of interest by a super-resolution microscopy.

Abstract: A method for producing a formed wooden article by cutting out a primary blank member from a raw wood and forming the same into a final three-dimensional shape having a substantially uniform thickness, comprises: a primary compression step in which the primary blank member is compressed by primary molding dies, and the primary blank member is processed into a primary compressed article having a high compression portion in a vicinity of portions of the primary blank member corresponding to a die surface; a secondary blank processing step in which the primary compressed article is cut and processed into a secondary blank member; and a secondary compression step in which the secondary blank member is compressed by using secondary molding dies and the final three-dimensional shape is transferred onto the secondary blank member.

Abstract: The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula —X-A (wherein X indicates a single bond, an optionally substituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).

Abstract: The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula —X-A (wherein X indicates a single bond, an optionally substituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).

Abstract: In order to provide a method and apparatus for forming a sheet metal, in which a three-dimensional product such as a prototype for commercialized press-forming can be formed in short time without limitations as to the shape and with high accuracy, preventing body wrinkles or reduction of the sheet thickness, a process of: performing drawing-forming to a predetermine height by pushing the forming punch having a desired shape in the sheet thickness direction with the edges of the blank workpiece being clamped; performing shape-forming with the shaping tool in the opposite side to the forming punch by increasing a clamping pressure to lock movement of a material with the forming punch being pushed; performing drawing-forming again by decreasing the clamping pressure and raising the forming punch by a desired height; and performing shape-forming with the shaping tool by increasing the clamping pressure to lock movement of a material, is repeated at least once.

Abstract: [Object] An underdrive-type single action press capable of saving energy, saving space, and realizing high-precision formability in a well-balanced manner is provided. Particularly, a press capable of shortening a forming stroke, reducing overall height, exactly correcting the deflection of the slide or dies to improve adhesion of the dies to a workpiece, and realizing pressure equalization of a wrinkle holder is provided.

Abstract: In order to provide a method and apparatus for forming a sheet metal, in which a three-dimensional product such as a prototype for commercialized press-forming can be formed in short time without limitations as to the shape and with high accuracy, preventing body wrinkles or reduction of the sheet thickness, a process of: performing drawing-forming to a predetermine height by pushing the forming punch having a desired shape in the sheet thickness direction with the edges of the blank workpiece being clamped; performing shape-forming with the shaping tool in the opposite side to the forming punch by increasing a clamping pressure to lock movement of a material with the forming punch being pushed; performing drawing-forming again by decreasing the clamping pressure and raising the forming punch by a desired height; and performing shape-forming with the shaping tool by increasing the clamping pressure to lock movement of a material, is repeated at least once.

Abstract: A method for producing a formed wooden article by cutting out a primary blank member from a raw wood and forming the same into a final three-dimensional shape having a substantially uniform thickness, comprises: a primary compression step in which the primary blank member is compressed by primary molding dies, and the primary blank member is processed into a primary compressed article having a high compression portion in a vicinity of portions of the primary blank member corresponding to a die surface; a secondary blank processing step in which the primary compressed article is cut and processed into a secondary blank member; and a secondary compression step in which the secondary blank member is compressed by using secondary molding dies and the final three-dimensional shape is transferred onto the secondary blank member.

Abstract: The present invention provides a novel compound exhibiting an excellent inhibitory action on AMPA receptor and/or kainate receptor. That is, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. In the formula, A1, A2 and A3 are independent of each other and each represents a C3-8 cycloalkyl group, a C3-8 cycloalkenyl group, a 5- to 14-membered non-aromatic heterocyclic group, a C6-14 aromatic hydrocarbon cyclic group or a 5- to 14-membered aromatic heterocyclic group, each of which may be substituted; Q represents O, S or NH; Z represents C or N; X1, X2 and X3 are independent of each other and each represents a single bond, an optionally substituted C1-6 alkylene group, an optionally substituted C2-6 alkenylene group, an optionally substituted C2-6 alkynylene group, —NH—, —O—, —NHCO—, —CONH—, —SO0-2—, etc.

Abstract: The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula —X-A (wherein X indicates a single bond, an optionally sbutituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).

Abstract: The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula —X-A (wherein X indicates a single bond, an optionally substituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).

Abstract: The invention provides a method and an apparatus capable of accurately shaping, within a short time, cubic products such as trial products for press molding for mass production without limitation of a molding shape. While edge portions of a blank are clamped, a mold punch having a molding shape is pushed from a sheet thickness direction to conduct rough forming. While the mold punch is kept pushed, shaping is conducted by use of a rod-like tool from an opposite side to the mold punch sandwiching the sheet thickness.

Abstract: The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof.

Abstract: The present invention provides a novel compound exhibiting an excellent inhibitory action on AMPA receptor and/or kainate receptor. That is, it provides a compound represented by the following formula, a salt thereof or a hydrate of them.

Abstract: The invention relates to an apparatus for the dieless forming of a sheet. The apparatus comprises a pressing mechanism and a sheet holding mechanism which are moved with respect to each other in X, Y and Z-axis directions and has a fixed ceiling plate form having a plane shape matching the bottom profile of a product to be formed; a framelike support plate surrounding the ceiling plate form is raised and lowered by at least one pair of raising/lowering actuators, and restraining actuators apply a controllable restraining force to the sheet byway of a framelike restraining plate clamping the periphery of the sheet in the sheet thickness direction between itself and the support plate. A mechanism for causing the support plate to undergo balanced movement and a material flow control mechanism may be preferably further provided.

Abstract: A method for continuously producing pipes, each having a polygon-shaped closed cross-section taken perpendicularly to the feeding direction of a strip of metal, which are free from brittleness caused by metal fatigue, and have good precision. A feed-bending method of successively feeding a strip of metal (work) W between a main die body, mandrel, punch and correction punches by predetermined feed lengths, and pressing the work W with these members synchroously with feeding is performed. The work W is gradually bent along designed ridgelines L1 through L2 extending in the feeding direction and defining ridgelines L5 through L8 of a product pipe W1, from the ridgelines L1 and L2 close to widthwise ends e1 and e2 to the ridgelines L3 and L4 in the widthwise center thereof in the course between the vicinity of an inlet and the vicinity of a middle of a device, and then, a resulting rough pipe W0 is corrected from the inside and outside thereof in the vicinity of an outlet of the device.

Abstract: An inverting machine for inverting metal molds 180.degree. including a bed, a stationary table on the bed, a pair of portal uprights standing on the table's lateral sides, a pair of slide frames slidably movable along the uprights, an inverting table provided between the slide frames and having a fixed securing element for holding a metal mold to be inverted, the inverting table being arranged in opposition to the stationary table, and a central shaft being pivotally supported by the slide frames and extending from a center of the width of each side of the inverting table. The ends of the central shaft are pivoted to rotate the inverting table about the central shaft. The slide frames are moved vertically relatively to the uprights. Pivoting and vertical moving may be done concurrently.