Abstract: A wire harness includes a shielded electric wire that includes a first coated electric wire that includes a first core electric wire and a first insulating coating that covers the first core electric wire, an electromagnetic shield member that covers the first coated electric wire, a sheath that covers the electromagnetic shield member, and a shield member exposed portion from which the sheath is removed and the electromagnetic shield member is exposed, an insulating cover that covers the shield member exposed portion, and a waterproofing agent applied to the shield member exposed portion and permeated into the electromagnetic shield member. The waterproofing agent is in tight contact with an inner circumferential surface of the sheath and an outer circumferential surface of the first insulating coating. The cover covers a portion of the shield member exposed portion.

Abstract: A route-regulating member according to an exemplary aspect is configured to be applied to a wire harness that includes a wire, and configured to regulate a route of the wire inserted therein, the route-regulating member including: a tube; and a tube connector having a curve, to which an end of the tube is connected.

Abstract: A route restriction member for a wire harness for accommodating an electrical wire and restricting a route of the electrical wire, the route restriction member including: a tube in which the electrical wire is accommodated, the tube includes: a first member made of metal, and a second member made of metal that is abutted against the first member to form the tube; and a fastening band that fastens an outer periphery of the tube, wherein abutments of the first member and the second member that are abutted against each other engage the fastening band with a protrusion/recess relationship therebetween.

Abstract: A wire harness including: an electrical wire including a core wire and a covering that covers an outer circumference of the core wire; and a routing path regulator that has a higher rigidity than the core wire and is configured to regulate a routing path of the electrical wire by being provided adjacent to the core wire between ends of the core wire and being covered, together with the core wire, by the covering.

Abstract: A route restriction member for a wire harness for accommodating an electrical wire and restricting a route of the electrical wire, the route restriction member including: a tube in which the electrical wire is accommodated, the tube includes: a first member made of metal, and a second member made of metal that is abutted against the first member to form the tube; and a fastening band that fastens an outer periphery of the tube, wherein abutments of the first member and the second member that are abutted against each other engage the fastening band with a protrusion/recess relationship therebetween.

Abstract: A route-regulating member according to an exemplary aspect is configured to be applied to a wire harness that includes a wire, and configured to regulate a route of the wire inserted therein, the route-regulating member including: a tube; and a tube connector having a curve, to which an end of the tube is connected.

Abstract: A wire harness including: an electrical wire including a core wire and a covering that covers an outer circumference of the core wire; and a routing path regulator that has a higher rigidity than the core wire and is configured to regulate a routing path of the electrical wire by being provided adjacent to the core wire between ends of the core wire and being covered, together with the core wire, by the covering.

Abstract: Apparatus and method for displaying menu lists and activating applications in conjunction with electronic devices that respectively load contents and an information device that reproduces the contents stored in the electronic devices. Connection to the electronic devices is detected, and a menu list is generated. The menu list automatically updates to include additional applications corresponding to electronic devices when connections to the electronic devices are respectively detected. This provides an updated menu list from which selection is made to activate a predetermined application to perform an operation related to the relevant electronic device.

Abstract: The present invention identified OVARC1000473 (SEQ ID NO: 1) and NT2RM1000377 (SEQ ID NO: 3) as clones showing suppression of CREB activation by forskolin, and provides evaluation methods using these genes, and/or proteins encoded by these genes. Furthermore, these proteins were found to enhance cell damage. Compounds that can be screened based on the evaluation methods of this invention are useful as agents for inhibiting the CREB dephosphorylation reaction, agents for suppressing enhancement of cell damage, and preventive and therapeutic agents for memory disorders and/or neurodegenerative disorders.

Abstract: A method of highly efficiently transferring various selected molecules into various cells and a method of fusing cells. Cells and/or selected molecules such as polynucleotide are treated with cold gas plasma to thereby transfer the selected molecules located around cells into the cells, or cells are fused by treating the cells with cold gas plasma. Moreover, an apparatus for transferring selected molecules or fusing cells having a cold gas plasma generation unit for transferring selected molecules into cells is provided.

Abstract: A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 22 that blocks off and allows the supply of power from the power supply circuit 20 to the step-up transformer 30 and which generates an instantaneous high voltage, and a pair of electrode probes 50 for applying the instantaneous high voltage generated at the step-up transformer 30 to a predetermined region in a body. The molecule introducing apparatus oscillates DNA arranged outside a cell by the instantaneous high voltage so as to introduce the DNA into the cell.

Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.

Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.

Abstract: The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-? protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-? protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-? protein.

Abstract: The present invention identified OVARC1000473 (SEQ ID NO: 1) and NT2RM1000377 (SEQ ID NO: 3) as clones showing suppression of CREB activation by forskolin, and provides evaluation methods using these genes, and/or proteins encoded by these genes. Furthermore, these proteins were found to enhance cell damage. Compounds that can be screened based on the evaluation methods of this invention are useful as agents for inhibiting the CREB dephosphorylation reaction, agents for suppressing enhancement of cell damage, and preventive and therapeutic agents for memory disorders and/or neurodegenerative disorders.

Abstract: The application display apparatus includes a connection terminal to which an electronic device having means for loading contents is connected, and the application display apparatus is an information device having a function for reproducing the contents stored in the electronic device by installing applications stored in an information medium; wherein the information device has; a function for detecting connection to the electronic device; a function for displaying a list of menu for activating only an application corresponding to the electronic device connected to the information device; and a function for activating a predetermined application by selecting a desired operation from the list of menu.

Abstract: Disclosed is an image fixing apparatus for use in an image forming apparatus for forming an image on a recording medium. During a process of continuously forming an image on a plurality of recording media, the recording medium feeding speed is switched when the temperature of a fixing roller has dropped to a particular value which is set depending on the rate at which the temperature of the fixing roller drops.

Abstract: A method of highly efficiently transferring various selected molecules into various cells and a method of fusing cells. Cells and/or selected molecules such as polynucleotide are treated with cold gas plasma to thereby transfer the selected molecules located around cells into the cells, or cells are fused by treating the cells with cold gas plasma. Moreover, an apparatus for transferring selected molecules or fusing cells having a cold gas plasma generation unit for transferring selected molecules into cells is provided.

Abstract: Methods of screening for iNOS activity inhibitors are provided using the binding activity of candidate compounds towards the iNOS monomer (or a mutant thereof) as an index. Dimerization of iNOS is the final step in the acquisition of iNOS enzyme activity. The screening methods according to this invention enable quick screening of iNOS inhibitory compounds that have excellent specificity and rapid action properties through simple manipulations.

Abstract: A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 22 that blocks off and allows the supply of power from the power supply circuit 20 to the step-up transformer 30 and which generates an instantaneous high voltage, and a pair of electrode probes 50 for applying the instantaneous high voltage generated at the step-up transformer 30 to a predetermined region in a body. The molecule introducing apparatus oscillates DNA arranged outside a cell by the instantaneous high voltage so as to introduce the DNA into the cell.