Abstract: A nerve stimulation apparatus includes: an intravascular stimulation electrode that transfers electric energy from inside of a blood vessel to a vagus nerve outside of the blood vessel; an intravascular heartbeat detection electrode that detects heartbeat information inside the blood vessel; and a notification member, in which calculating a heart rate reduction rate on the basis of a pre-stimulation heart rate HR_base based on the heartbeat information detected prior to output of the electric energy and an in-stimulation heart rate HR_st based on the heartbeat information detected during output of the electric energy; making the notification member notify the heartbeat status in a case in which at least the heart rate reduction rate is less than the first threshold value; and stops the stimulus output generating circuit from outputting the electric energy in a case in which the heart rate reduction rate is no as than the first threshold value.

Abstract: An electrostimulation system includes a connector connected to an electrostimulation device, a conducting wire pair electrically connected to the connector, an electrical stimulation lead having a sheathing body configured to insulate the conducting wire pair and installed to be inserted into the vein, an electrical stimulus block portion installed at a leading end side of the electrical stimulation lead and having an electrode portion electrically connected to the conducting wire pair and a fixing block configured to bias the electrode portion to the inner wall of the vein, and a rotary member having an engaging groove detachably engaged with the electrical stimulus block portion and configured to rotate the electrical stimulus block portion disposed in the vein about a central axis of the vein disposed in the vein via the engaging groove.

Abstract: An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method.

Abstract: A nerve stimulation electrode implantation system includes: an introduction portion that has a cylindrical main body which has an internal cavity, and an incision component which has a blunt dissection portion that bluntly dissects biological tissue, and which is formed so as to be transparent, and which is attached to a distal end portion of the main body; an observation portion that is inserted into the introduction portion such that it is able to observe the periphery of the incision component through the incision component; and a peeling portion that is positioned such that it is able to rotate around its own axis and is able to move relatively in this axial direction relative to the introduction portion, and that removes peripheral tissue from the periphery of the nerve tissue.

Abstract: Provided is a defibrillation system including an electrode section that is attached to a heart and applies electrical energy to the heart, a defibrillator that generates the electrical energy on the basis of a predetermined defibrillation wave, and a lead that electrically connects the electrode section and the defibrillator. Further, the defibrillation wave includes a first wave generating first energy, a second wave generating second energy higher than the first energy of the first wave behind the first wave, and an application stop period formed between the first wave and the second wave.

Abstract: An electrostimulation system includes an electrostimulation lead which has a connector connected to an electrostimulation device, a conducting wire pair electrically connected to the connector, and a sheathing body insulating the conducting wire pair, and is provided to pass through a vein, an electrostimulation block portion which is provided on the leading end side of the electrostimulation lead, and has an electrode portion electrically connected to the conducting wire pair and fixing hooks urging the electrode portion toward the inner wall of the vein, and a rotary member which has an engagement groove to be detachably engaged with the electrostimulation block portion and rotates the electrostimulation block portion placed in the vein around the center line of the vein through the engagement groove.

Abstract: An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method.

Abstract: A cell culture detection apparatus includes a culture vessel that houses cells together with a culture liquid, a culturing device that cultures the cells under predetermined culturing conditions, a detection device that detects a feature of the cells among the cells being cultured, and a light blocking device that blocks the culture vessel from environmental light when the feature is not detected.

Abstract: An object of the present invention is to provide a method for introducing a physiologically active substance such as a gene into a cell, which introduces a physiologically active substance such as any given gene into any given cell in a view under a microscope, while significantly reducing invasiveness to the cell, and a device used for the above method. The present invention provides a method for introducing a physiologically active substance into a cell, which comprises: allowing a physiologically active substance to attach around a needle having a diameter of 500 nm or less, provided that it is able to be inserted into a cell; and inserting the above-described needle into the cell; and a microinjection device for carrying out the aforementioned method.

Abstract: A biorelated substance examination apparatus includes a reaction stage which supports a reaction vessel which contains the solid support and promotes a reaction of the solid-state phase, and a microscope which optically observes the solid support. The reaction stage includes a fluid transfer mechanism which transfers a fluid with respect to the reaction vessel and a temperature adjusting mechanism which adjusts a temperature of the solid support in the reaction vessel.

Abstract: An object is to provide a biological sample observation system wherein light damage to the biological sample is decreased, and observation can be performed accurately and quickly over a long period of time.

Abstract: A cell culture detection apparatus includes a culture vessel that houses cells together with a culture liquid, a culturing device that cultures the cells under predetermined culturing conditions, a detection device that detects a feature of the cells among the cells being cultured, and a light blocking device that blocks the culture vessel from environmental light when the feature is not detected.

Abstract: An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track.

Abstract: An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track.

Abstract: An optical pick-up head for reading writing information from on a magneto-optical record medium including a semiconductor laser, a multi-image plane parallel plate for separating an incident light beam emitted by the semiconductor laser from a return light beam reflected by the optical record medium and dividing the return beam transmitted through and refracted by the multi-image plane parallel plate into a plurality of return light beams, and a signal detecting photodetector receiving a plurality of return light beams, wherein the multi-image plane parallel plate is formed by first and second prisms made of birefringent material and is arranged such that major and minor axes of astigmatism introduced by the plane parallel plate are inclined by 45.degree. with respect to an information track.

Abstract: An optical pick-up apparatus for reproducing information recorded on a magneto-optical record medium including a semiconductor laser emitting a linearly polarized laser beam, and a polarizing film provided between a glass prism and a uniaxial birefringent crystal prism. The laser beam emitted by the semiconductor laser is made incident upon the polarizing film via the glass prism and is reflected thereby. The apparatus further includes an objective lens projecting the laser beam reflected by the polarizing film onto the magneto-optical record medium as a fine spot and converging a return laser beam reflected by the record medium toward the polarizing film. The return beam transmitted through the polarizing film is refracted by the uniaxial birefringent crystal prism and is divided into ordinary light and extraordinary light, which are received by a first photodetector to produce a reproduced information signal.

Abstract: An ultrasonic piezoelectric transducer and an ultrasonic actuator for performing enhanced elliptical vibration comprise a first laminated piezoelectric element having a first fixed end, a resonator mounted to the opposite end of the first laminated piezoelectric element, a second laminated piezoelectric element having one end thereof fixedly mounted to the resonator in a direction other than a vibrating direction of the first laminated piezoelectric element, and a load mass fixedly mounted to the opposite end of the second laminated piezoelectric element. This structure permits the enhanced elliptical vibration of the transducer to have a large, controllable amplitude.

Abstract: An ultrasonic motor comprising a vibrator for generating ultrasonic vibration, an electric-mechanical energy conversion element provided at node positions of the ultrasonic vibration, for generating ultrasonic vibration on the vibrator, the vibrator having an end face thereof which is inclined with respect to a central axis of the vibrator being rotatably driven by electric energy applied to the electric-mechanical energy conversion element, a plurality of displacement enlarging vibration pieces which are formed axially on the end face of the ultrasonic vibrator and in which grooves concentric with an outer periphery are arranged respectively at the node positions of the vibration, the displacement enlarging vibrating piece having a taper, and an element to be driven urged against end faces of the displacement enlarging vibration pieces by urging means and moved in a predetermined direction.

Abstract: An ultrasonic motor comprising an elastic body, at least two laminated piezoelectric bodies clamped by a portion of the elastic body, an ultrasonic oscillator for exciting simultaneously a plurality of shrunk and retreated oscillation modes on the elastic body, to generate ultrasonic elliptic oscillation, and an element to be driven urged against a portion of the ultrasonic oscillator and movable with respect to the ultrasonic oscillator.

Abstract: The present invention discloses an ultrasonic oscillator including: a plurality of resonators; and an electricity-to-mechanical energy conversion element disposed among a plurality of the resonators and pressed by a fastening member, wherein the ultrasonic oscillator bends and/or oscillates when alternating voltage is applied to the electricity-to-mechanical energy conversion element, and the resonators do not come in contact with the fastening member in a portion adjacent to the end surface of the ultrasonic oscillator.