Patents by Inventor Hiroyuki Izumi

Hiroyuki Izumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080312093
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in gastric carcinoma as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells among these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: December 18, 2008
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Publication number: 20080299184
    Abstract: It is an object of the present invention to provide a cancer-suppressing agent comprising a novel cancer-suppressing gene based on the discovery of such cancer-suppressing gene. The present invention provides A cancer-suppressing agent which comprises PCDH20 gene or a homologous gene thereof.
    Type: Application
    Filed: March 21, 2007
    Publication date: December 4, 2008
    Inventors: Issei Imoto, Johji Inazawa, Hiroyuki Izumi, Sana Yokoi
  • Publication number: 20080108061
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in brain tumor as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells among these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: May 8, 2008
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki, Itaru Sonoda
  • Publication number: 20080032943
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in thyroid carcinoma as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells among these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: February 7, 2008
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Publication number: 20080015160
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in pancreatic carcinoma as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells amond these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: January 17, 2008
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Publication number: 20070161019
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in lung cancer as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells amond these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: July 12, 2007
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki, Itaru Sonoda
  • Publication number: 20070161018
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in bile duct cancer as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells amond these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: July 12, 2007
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Publication number: 20070154916
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in myeloma as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells amond these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: July 5, 2007
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Publication number: 20070154915
    Abstract: An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in large intestine cancer as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells amond these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified.
    Type: Application
    Filed: November 2, 2006
    Publication date: July 5, 2007
    Inventors: Johji Inazawa, Issei Imoto, Jun Inoue, Akiko Furihata, Sana Yokoi, Itaru Sonoda, Hideaki Tanami, Hiroyuki Izumi, Kuniyasu Saigusa, Shin Hayashi, Hisashi Takada, Ayako Suzuki
  • Patent number: 7156061
    Abstract: A valve lifter, in which an amorphous hard carbon film is coated at least on the surface that slides against a cam, is characterized in that the surface of a base material (substrate) has an arithmetic mean roughness of Ra 0.01 to 0.03 micrometers, and the maximum length of the scratch on the base surface is made to be equal to or shorter than 250 micrometers.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: January 2, 2007
    Assignees: Kabushiki Kaisha Riken, Nissan Motor Co., Ltd.
    Inventors: Takashi Matsui, Masaki Moronuki, Katsuhiro Tsuji, Yutaka Mabuchi, Takahiro Hamada, Hiroyuki Izumi, Tomoyuki Koike
  • Publication number: 20060207540
    Abstract: A valve lifter, in which an amorphous hard carbon film is coated at least on the surface that slides against a cam, is characterized in that the surface of a base material (substrate) has an arithmetic mean roughness of Ra 0.01 to 0.03 micrometers, and the maximum length of the scratch on the base surface is made to be equal to or shorter than 250 micrometers.
    Type: Application
    Filed: February 1, 2006
    Publication date: September 21, 2006
    Inventors: Takashi Matsui, Masaki Moronuki, Katsuhiro Tsuji, Yutaka Mabuchi, Takahiro Hamada, Hiroyuki Izumi, Tomoyuki Koike
  • Patent number: 7061436
    Abstract: In an antenna device of the invention used for a wireless LAN, a first substrate with a conductive pattern formed thereon to function as a radiator and a second substrate with conductive patterns formed thereon to function as a wave director and a reflector are held respectively in an inner casing and in an outer casing of the antenna device in a slidable manner. The antenna device is attached to a top face of an access point by means of a three-dimensional joint. The user loosens a screw attached to the outer casing and slides the inner casing relative to the outer casing, so as to change the positional relation of the inner casing to the outer casing. The simple change of the positional relation readily switches over the directional characteristic of the antenna device between a first position where the wave director, the radiator, and the reflector are arranged in parallel across preset distances and the antenna device functions as a Yagi-Uda antenna having high directional characteristic with regard to 2.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: June 13, 2006
    Assignee: Buffalo Inc.
    Inventor: Hiroyuki Izumi
  • Publication number: 20050024276
    Abstract: In an antenna device of the invention used for a wireless LAN, a first substrate with a conductive pattern formed thereon to function as a radiator and a second substrate with conductive patterns formed thereon to function as a wave director and a reflector are held respectively in an inner casing and in an outer casing of the antenna device in a slidable manner. The antenna device is attached to a top face of an access point by means of a three-dimensional joint. The user loosens a screw attached to the outer casing and slides the inner casing relative to the outer casing, so as to change the positional relation of the inner casing to the outer casing. The simple change of the positional relation readily switches over the directional characteristic of the antenna device between a first position where the wave director, the radiator, and the reflector are arranged in parallel across preset distances and the antenna device functions as a Yagi-Uda antenna having high directional characteristic with regard to 2.
    Type: Application
    Filed: June 30, 2004
    Publication date: February 3, 2005
    Inventor: Hiroyuki Izumi
  • Patent number: 6034351
    Abstract: A cleaning arrangement for removing sputter attached to a welding torch nozzle includes a cylindrical container with screen at the lower end thereof, shot material held by the screen, an air injection nozzle disposed above the screen, a suction tube under the nozzle and a torch nozzle sensor to control the sputter removal process.
    Type: Grant
    Filed: June 24, 1998
    Date of Patent: March 7, 2000
    Inventors: Katsuhiro Sato, Hiroyuki Izumi, Motoaki Maruyama, Toshiya Hayashida, Yusuke Harayama, Kenji Yoshida, Kenji Hiroi
  • Patent number: 5594836
    Abstract: An ennoversion management system is adapted to a data processing system executes a desired process by naming as objects single processing units and/or composite processing units which are combinations of the single processing units and combining the objects. In the ennoversion management system, a real world is understood as an object model, the real world is made to correspond to an extension and a connotation, the connotation is placed in an information concealed region, and ID information which specifies the connotation in correspondence with the extension is formed. The real world is described by a dynamic world and a static world forming a world of the objects in correspondence with the extension, a system mechanism is given as a static model with respect to the static world using classes and/or composite classes, and a session corresponding to a motion of the dynamic model is given as a dynamic model with respect to the dynamic world using instances of the composite classes and/or the classes.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: January 14, 1997
    Assignee: Fujitsu Limited
    Inventors: Tadamitsu Ryu, Hiroyuki Izumi, Masahiko Murakawa, Masanobu Toyota, Takeshi Adachi, Naomi Ichikawa
  • Patent number: 5572733
    Abstract: A data processing system for executing a process. Classes and composite classes are formed by combining methods. Instances are formed and correspond to the classes and composite classes. The real world is analyzed as an object model which includes a static world, a dynamic world and a cause and effect relationship. The object model has a corresponding extension and a corresponding connotation. The connotation is in an information concealed region, and identification information identifies the extension and connotation. A system mechanism is created with respect to the static world using the classes and composite classes, where the system mechanism is a static model for the static world. The instances are used to form a session corresponding to motion with respect to the dynamic world, where the session is a dynamic model for the dynamic world. The cause and effect relationship of the object model is generated from the dynamic model into the static model.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: November 5, 1996
    Assignee: Fujitsu Limited
    Inventors: Tadamitsu Ryu, Hiroyuki Izumi, Masahiko Murakawa, Masanobu Toyota, Takeshi Adachi, Naomi Ichikawa
  • Patent number: 5560012
    Abstract: An object-oriented data processing system includes a link setting unit for setting a link between a plurality of composite objects to provide a structure to a static model and a dynamic model such that the link includes: a strong link that causes an automatic propagation of an operation applied to a composite object, to another composite object connected by the strong link; and a weak link wherein propagation of an operation applied to a composite object occurs to another composite object connected by the weak link, conditionally.
    Type: Grant
    Filed: May 25, 1994
    Date of Patent: September 24, 1996
    Assignee: Fujitsu Limited
    Inventors: Tadamitsu Ryu, Hiroyuki Izumi, Masahiko Murakawa, Masanobu Toyota, Takeshi Adachi, Naomi Ichikawa
  • Patent number: 5546149
    Abstract: A focal plane shutter for a camera comprises opening and closing blade units operable to open and close a shutter opening of the camera. Each blade unit has a leading blade and trailing blades in superposed relation to the leading blade. The leading blade and the trailing blades are supported by arm members through hollow pivot pins. The hollow pivot pins supporting the leading blade of each blade unit are covered by the trailing blades. Due to the use of hollow pivot pins, the overall weight and driving force of the blade units are effectively reduced to thereby make the shutter free of operational impact without light leakage.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: August 13, 1996
    Assignee: Seiko Precision Inc.
    Inventors: Ichiro Nemoto, Hiroyuki Izumi, Nobuyuki Fukui, Kunioki Takahashi
  • Patent number: 5214463
    Abstract: A focal plane shutter has at least one shutter blade group comprised of a leading blade and a set of trailing blades. A first parallel link mechanism is pivotally connected at two spaced locations to the leading blade to effect displacement of the leading blade relative to a shutter opening. A second parallel link mechanism is pivotally connected at two or more spaced locations to the set of trailing blades to effect displacement of the trailing blades relative to the shutter opening. The distance between the two pivotal connections of the first parallel link mechanism is greater than the distance between the at least two pivotal connections of the second parallel link mechanism.
    Type: Grant
    Filed: March 29, 1991
    Date of Patent: May 25, 1993
    Assignee: Seikosha Co., Ltd.
    Inventors: Hiroaki Ishida, Ichiro Nemoto, Hiroyuki Izumi