Patents by Inventor Hiroyuki Kabata

Hiroyuki Kabata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10702864
    Abstract: Disclosed is a solid-liquid separation method including: sucking a suspension containing particles, through an opening formed at a leading end of a suction nozzle, into the suction nozzle; allowing at least a part of the particles contained in the sucked suspension, to sediment to be clogged in the suction nozzle; and ejecting a liquid inside the suction nozzle, through the opening of the suction nozzle clogged with the particles.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: July 7, 2020
    Assignees: Sysmex Corporation, Mitsubishi Chemical Corporation
    Inventors: Satomi Kishimoto, Hiroyuki Kabata, Takanobu Katsuki
  • Publication number: 20180345272
    Abstract: Disclosed is a solid-liquid separation method including: sucking a suspension containing particles, through an opening formed at a leading end of a suction nozzle, into the suction nozzle; allowing at least a part of the particles contained in the sucked suspension, to sediment to be clogged in the suction nozzle; and ejecting a liquid inside the suction nozzle, through the opening of the suction nozzle clogged with the particles.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Satomi Kishimoto, Hiroyuki Kabata, Takanobu Katsuki
  • Patent number: 10119980
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: November 6, 2018
    Assignees: SYSMEX CORPORATION, Kagoshima University
    Inventors: Hiroyuki Kabata, Hideki Takahashi, Rena Tsuruoka, Ikuro Maruyama
  • Patent number: 10053488
    Abstract: Disclosed is a method of liberating a peptide, the method comprising a step of bringing a self-aggregate of albumin containing a peptide incorporated therein into contact with a solution that contains a compound represented by Formula (I) or (II) defined in the specification at a concentration of 80 mM to 1000 mM and allowing the peptide to be liberated from the self-aggregate of albumin into the solution.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: August 21, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Rena Tsuruoka, Sanai Tsunokuni, Yukiko Miura, Hiroyuki Kabata
  • Patent number: 9624263
    Abstract: Disclosed is a method of recovering a peptide including: mixing a liquid sample containing a complex of peptide and protein in blood with a reagent containing at least one selected from the group consisting of Zn2+, Ca2+, Li+, Ba2+, Mg2+, Mn2+, and a metal compound that forms any of these metal ions to liberate the peptide from the protein in blood; and recovering the liberated peptide.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: April 18, 2017
    Assignee: SYSMEX CORPORATION
    Inventors: Atsushi Iwai, Sanai Tsunokuni, Kana Kawasaki, Hiroyuki Kabata
  • Publication number: 20170089928
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Application
    Filed: December 15, 2016
    Publication date: March 30, 2017
    Applicants: SYSMEX CORPORATION, Kagoshima University
    Inventors: Hiroyuki KABATA, Hideki TAKAHASHI, Rena TSURUOKA, Ikuro MARUYAMA
  • Publication number: 20170057991
    Abstract: Disclosed is a method of liberating a peptide, the method comprising a step of bringing a self-aggregate of albumin containing a peptide incorporated therein into contact with a solution that contains a compound represented by Formula (I) or (II) defined in the specification at a concentration of 80 mM to 1000 mM and allowing the peptide to be liberated from the self-aggregate of albumin into the solution.
    Type: Application
    Filed: August 24, 2016
    Publication date: March 2, 2017
    Applicant: SYSMEX CORPORATION
    Inventors: Rena TSURUOKA, Sanai TSUNOKUNI, Yukiko MIURA, Hiroyuki KABATA
  • Publication number: 20160033500
    Abstract: Disclosed is a device for determining a type of target peptide includes: an acquisition unit that obtains first to third information on a target peptide contained in a test sample; a storage unit that stores first to third information on a known peptide obtained using a standard sample containing the known peptide; and a controller programmed to perform operations including: comparing the first to third information on the target peptide obtained from the test sample with the first to third information on the known peptide stored in the storage unit; and determining whether or not the target peptide is the known peptide, wherein the first information is a dissociation rate constant when the target peptide dissociates from a protein, in a solid phase carrier in which the target peptide is immobilized on a support through the protein binding to a peptide, the second information is a maximum value of a layer thickness change amount on the support, and the third information is information indicating that a dissoci
    Type: Application
    Filed: July 28, 2015
    Publication date: February 4, 2016
    Applicant: SYSMEX CORPORATION
    Inventors: Yukiko MIURA, Hiroyuki KABATA
  • Publication number: 20150210736
    Abstract: Disclosed is a method of recovering a peptide including: mixing a liquid sample containing a complex of peptide and protein in blood with a reagent containing at least one selected from the group consisting of Zn2+, Ca2+, Li+, Ba2+, Mg2+, Mn2+, and a metal compound that forms any of these metal ions to liberate the peptide from the protein in blood; and recovering the liberated peptide.
    Type: Application
    Filed: January 21, 2015
    Publication date: July 30, 2015
    Applicant: SYSMEX CORPORATION
    Inventors: Atsushi IWAI, Sanai TSUNOKUNI, Kana KAWASAKI, Hiroyuki KABATA
  • Patent number: 9090896
    Abstract: The present invention relates to a molecule capable of binding to adrenocorticotropic hormone (ACTH) with high affinity. The present invention also relates to use of the molecule for detection and/or purification of ACTH.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: July 28, 2015
    Assignee: SYSMEX CORPORATION
    Inventors: Katsunori Itoh, Hiroyuki Kabata
  • Publication number: 20140322821
    Abstract: The present invention relates to a molecule capable of binding to adrenocorticotropic hormone (ACTH) with high affinity. The present invention also relates to use of the molecule for detection and/or purification of ACTH.
    Type: Application
    Filed: June 26, 2014
    Publication date: October 30, 2014
    Applicant: SYSMEX CORPORATION
    Inventors: Katsunori ITOH, Hiroyuki KABATA
  • Patent number: 8765397
    Abstract: A cell dispersion method, a cell dispersing agent and a cell measurement method, each of which can disperse a cell mass while reducing damage to a cell are provided. Upon dispersing a cell mass, a fluororesin particle is used. A cell mass composed of an aggregated of multiple cells is mixed with a fluororesin particle in a liquid medium, thereby separating the cell mass into individual cells to disperse the cells. In addition, the dispersed cells are measured by flow cytometry, thereby carrying out cell measurement.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: July 1, 2014
    Assignee: Sysmex Corporation
    Inventor: Hiroyuki Kabata
  • Patent number: 8716440
    Abstract: A novel method capable of liberating a peptide from a complex of peptide and albumin and the associated method of recovering the peptide are provided. When a liquid sample containing a complex of peptide and albumin undergoes heat treatment, a self-aggregate of albumin formed in the liquid sample. The peptide is simultaneously liberated from the complex and recovered by removing the self-aggregate from the liquid sample.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: May 6, 2014
    Assignee: Sysmex Corporation
    Inventors: Yuta Yamamoto, Kana Kawasaki, Hiroyuki Kabata
  • Publication number: 20130295689
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Application
    Filed: June 12, 2013
    Publication date: November 7, 2013
    Inventors: Hiroyuki KABATA, Hideki TAKAHASHI, Rena TSURUOKA, Ikuro MARUYAMA
  • Patent number: 8486716
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: July 16, 2013
    Assignees: Sysmex Corporation, Kagoshima University
    Inventors: Hiroyuki Kabata, Hideki Takahashi, Ikuro Maruyama, Rena Tsuruoka
  • Publication number: 20120277407
    Abstract: A novel method capable of liberating a peptide from a complex of peptide and albumin and the associated method of recovering the peptide are provided. When a liquid sample containing a complex of peptide and albumin undergoes heat treatment, a self-aggregate of albumin formed in the liquid sample. The peptide is simultaneously liberated from the complex and recovered by removing the self-aggregate from the liquid sample.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 1, 2012
    Applicant: SYSMEX CORPORATION
    Inventors: Yuta YAMAMOTO, Kana KAWASAKI, Hiroyuki KABATA
  • Publication number: 20120244634
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Application
    Filed: June 7, 2012
    Publication date: September 27, 2012
    Applicants: KAGOSHIMA UNIVERSITY, SYSMEX CORPORATION
    Inventors: Hiroyuki KABATA, Hideki TAKAHASHI, Ikuro MARUYAMA, Rena TSURUOKA
  • Publication number: 20110117593
    Abstract: A cell dispersion method, a cell dispersing agent and a cell measurement method, each of which can disperse a cell mass while reducing damage to a cell are provided. Upon dispersing a cell mass, a fluororesin particle is used. A cell mass composed of an aggregated of multiple cells is mixed with a fluororesin particle in a liquid medium, thereby separating the cell mass into individual cells to disperse the cells. In addition, the dispersed cells are measured by flow cytometry, thereby carrying out cell measurement.
    Type: Application
    Filed: July 10, 2009
    Publication date: May 19, 2011
    Applicant: Sysmex Corporation
    Inventor: Hiroyuki Kabata