Abstract: An engine controller for a vehicle is provided, the engine controller having a tilt angle sensor incorporated therein. The tilt angle sensor is operatively connected to an electronic control unit via a signal line. The electronic control unit is operable to temporarily interrupt the operations of a fuel injector and/or an ignition coil when a tilt angle signal is input via the signal line when the tilt angle signal indicates a tilt angle in excess of a predetermined value. As a result of this configuration, the number of required parts is reduced and available space on the vehicle is used effectively.

Abstract: There is provided a heteroaryl 5-thio-?-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.

Abstract: There is provided a 5-thio-?-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.

Abstract: The present invention provides a 1-thio-D-glucitol compound of the following formula, which shows the action of inhibiting the activity of SGLT2, a pharmaceutically acceptable salt of the compound, or a hydrate of the compound or the salt; and a pharmaceutical comprising such a compound as an active ingredient, especially, a pharmaceutical for preventing or treating diabetes, diabetes-related disease, or diabetic complication. The invention also provides a method for producing the 1-thio-D-glucitol compound and its intermediate.

Abstract: Data driver modules are connected to a driver controller. In driver-data output clock selection sections and driver data control sections, each equal in number to the data driver modules that are connected to the driver controller, the phase of driver data is adjusted for each data driver module, while the phase of each driver clock is adjusted in driver-clock output clock selection sections and driver clock control sections.

Abstract: An N-hydroxyformamidine compound of the following formula or a pharmaceutically acceptable salt thereof: wherein R1, A and R are as defined herein. The compounds inhibit 20-HETE-producing enzymes, 20-HETE being involved in the effects of causing microvascular constriction or dilation in major organs (e.g., kidneys, cerebral blood vessels) or of inducing cell proliferation.

Abstract: The present invention provides a method for preparing an aryl 5-thio-?-D-aldohexopyranoside derivative of Formula (III), which comprises reacting a 5-thio-D-aldohexopyranose derivative of Formula (I) with Ar-OH of Formula (II) in the presence of a phosphine represented by PR11R12R13 and an azo reagent represented by R21—N?N—R22 in accordance with the following scheme

Abstract: A vehicle-mounted internal combustion engine controller is provided that can properly stop an internal combustion engine in accordance with an operational state no matter whether a vehicle body is inclined. The vehicle-mounted internal combustion engine controller comprises an inclination sensor for detecting vehicle body inclination; a mechanism for determining the operational state of a combustion engine; and a controller for stopping the operation of the combustion engine in accordance with a vehicle body inclination and an operational state. The cutoff mechanism stops the operation of the vehicle-mounted internal combustion engine when it is judged that a vehicle body inclination angle ? detected by the inclination sensor is greater than a predetermined angle A for a greater or equal period of time as a threshold stop time T1, T2 setting, which varies with the operational state determined by the operational state sensor.

Abstract: There is provided a heteroaryl 5-thio-?-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.

Abstract: An engine controller for a vehicle is provided, the engine controller having a tilt angle sensor incorporated therein. The tilt angle sensor is operatively connected to an electronic control unit via a signal line. The electronic control unit is operable to temporarily interrupt the operations of a fuel injector and/or an ignition coil when a tilt angle signal is input via the signal line when the tilt angle signal indicates a tilt angle in excess of a predetermined value. As a result of this configuration, the number of required parts is reduced and available space on the vehicle is used effectively.

Abstract: A vehicle-mounted internal combustion engine controller is provided that can properly stop an internal combustion engine in accordance with an operational state no matter whether a vehicle body is inclined. The vehicle-mounted internal combustion engine controller comprises an inclination sensor for detecting vehicle body inclination; a mechanism for determining the operational state of a combustion engine; and a controller for stopping the operation of the combustion engine in accordance with a vehicle body inclination and an operational state. The cutoff mechanism stops the operation of the vehicle-mounted internal combustion engine when it is judged that a vehicle body inclination angle a detected by the inclination sensor is greater than a predetermined angle A for a greater or equal period of time as a threshold stop time T1, T2 setting, which varies with the operational state determined by the operational state sensor.

Abstract: An N-hydroxyformamidine derivative of the following formula or a pharmaceutically acceptable salt thereof: (wherein R1 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkoxy group or a halogen atom, A represents a C1-10 alkylene group or a group of the following formula: (wherein m, n and p each represent an integer of 0 to 4), and R represents an N,N-di-C1-6 alkylamino group, a dioxanyl group, a C1-4 alkyl-substituted dioxanyl group, a C1-4 alkoxy-C1-4 alkoxy group or a group of the following formula: (wherein s and t each represent an integer of 1 to 4, B represents a methylene group, an oxygen atom, a sulfur atom, a nitrogen atom, a C1-4 alkyl-substituted nitrogen atom, a phenyl-substituted nitrogen atom or a benzyl-substituted nitrogen atom, R2 represents a hydrogen atom or a C1-4 alkyl group, and r represents an integer of 0 to 2)).

Abstract: The present invention provides a method for preparing an aryl 5-thio-?-D-aldohexopyranoside derivative of Formula (III), which comprises reacting a 5-thio-D-aldohexopyranose derivative of Formula (I) with Ar—OH of Formula (II) in the presence of a phosphine represented by PR11R12R13 and an azo reagent represented by R21—N?N—R22 in accordance with the following scheme.

Abstract: There is provided a 5-thio-?-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.

Abstract: In an automatic decompression device for an engine, having a decompression cam supported on a camshaft adjacent to a valve operating cam for movement between a biased valve opening position in which the decompression cam causes a cam surface to project beyond a base circle portion of the valve operating cam to bias open an exhaust valve or an intake valve in a compression stroke of the engine, and a retracted position in which the decompression cam retracts the cam surface inwardly of the base circle portion of the valve operating cam under centrifugal forces acting on the counterweight against spring forces of a spring when the engine operates at a relatively high rotational speed, to prevent oil from being trapped between the decompression cam and the camshaft and allow the decompression cam to operate smoothly to decompress the engine when the engine starts at low temperatures.