Abstract: The present invention herein provides a compound which promotes drug-permeation into nails. A penetrating promoter comprises, for instance, the following formulas. R1, R2 and R3 are alkyl groups having a carbon number of 1 to 15 and have OH groups at their ends.

Abstract: The present invention herein provides a 2-pyridone derivative which has a cell adhesion-inhibitory activity and which is useful for preventing and/or treating pathema or disease conditions including, for instance, inflammations which relate to leukocytic infiltration. The 2-pyridone derivative is a compound represented by the following general formula (1). In the formula, R1 represents, for instance, a phenyl or pyridyl group, R2 represents, for instance, a phenyl group, R3 represents, for instance, a lower alkyl group, R4 represents, for instance, a lower alkyl group, R5 represents, for instance, a lower alkyl group, and R6 represents, for instance, a lower alkyl group.

Abstract: An object is to provide a redundant supervisory control system and a redundancy switching method thereof. In the redundant supervisory control system, remote I/O apparatuses are less likely to be inaccessible, even in a case where failures occur in plural locations. Thus, the reliability of the system is enhanced. The redundant supervisory control system including a plurality of first loop interface units in each of a pair of controllers, second loop interface units, and communication cables each connecting the plurality of first and second loop interface units with one another in a circular loop. The redundant supervisory control system is configured by connecting the controllers and the remote I/O units to one another in a plurality of loop networks. In a case where abnormality in the loop networks is detected by use of received data in the networks, the first and second loop interface units that can perform normal reception are automatically selected.

Abstract: An object is to provide a redundant supervisory control system and a redundancy switching method thereof. In the redundant supervisory control system, remote I/O apparatuses are less likely to be inaccessible, even in a case where failures occur in plural locations. Thus, the reliability of the system is enhanced. The redundant supervisory control system including a plurality of first loop interface units in each of a pair of controllers, second loop interface units, and communication cables each connecting the plurality of first and second loop interface units with one another in a circular loop. The redundant supervisory control system is configured by connecting the controllers and the remote I/O units to one another in a plurality of loop networks. In a case where abnormality in the loop networks is detected by use of received data in the networks, the first and second loop interface units that can perform normal reception are automatically selected.

Abstract: The present invention provides a 4-oxoquinolizine antibacterial agent having a 2-pyridone skeleton as a partial structure and also having a strong antibacterial effect on gram-positive bacteria, gram-negative bacteria or anaerobic bacteria. The compound having the following formula (I) or a pharmaceutically acceptable salt thereof: wherein: R1 represents hydrogen atom or a carboxyl-protecting group, R2 represents hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxyl group or hydroxyl group, R3 represents phenyl group or an aromatic substituent selected from the group consisting of 5-membered and 6-membered heterocyclic groups and R3 has a substituent selected from the group consisting of a hydrogen atom, a lower alkyl group, a lower alkoxyl group, a nitro group, a cyano group, an amino group, an acyl group, a carbamoyl group and a ureido group, and R4 represents a hydrogen atom or a halogen atom.

Abstract: The present invention provides a 4-oxoquinolizine antibacterial agent having a 2-pyridone skeleton as a partial structure and also having a strong antibacterial effect on gram-positive bacteria, gram-negative bacteria or anaerobic bacteria.

Abstract: A compound represented by the following Formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or a carboxyl-protecting group, R2 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a hydroxyl group, R3 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group, a cyano group, a hydroxyl group or an amino group; R4 represents a hydrogen atom, an amino-protecting group, an alkyl group or a cycloalkyl group, and R5 represents a hydrogen atom, a halogen atom, an alkyl group, an alkenyl group, a cycloalkyl group, an aryl group, an alkoxy group, an alkylthio group, a hydroxyl group, an imino group or an amino group.

Abstract: A compound represented by the following Formula (I) or a pharmaceutically acceptable salt thereof: 1

Abstract: A programmable controller includes for controlling a system including a program memory unit for storing a group of sequence instructions including an instruction part and operand part, a data memory unit for storing a plurality of system data, a sequence execution control unit for executing sequence computations based on instructions fetched from the program memory unit and the system data from the data memory unit, and a holding register unit for holding the operand part as address part of the system data when the sequence execution control unit fetches the instruction from the program memory.

Abstract: A programmable controller is disclosed for controlling a system including a program memory unit for storing a group of sequence instructions including an instruction part and operand part, a data memory unit for storing a plurality of system data, a sequence execution control unit for executing sequence computations based on instructions fetched from the program memory unit and the system data from the data memory unit, and a holding register unit for holding the operand part as address part of the system data when the sequence execution control unit fetches the instruction from the program memory.

Abstract: A program memory and a data memory are independently arranged, and a holding register is arranged between the program memory and the data memory. The program memory and the holding register, the holding register and the data memory, and the data memory, a bit computation unit, and a numerical computation unit are respectively connected to each other through independent buses. After an operand address output from the program memory is latched by the holding register, the content of an instruction pointer for the program memory is updated. As a result, since an operand of the next instruction is set in a register file upon completion of execution of the first instruction, a processing speed can be increased.