Patents by Inventor Hiroyuki Matsueda

Hiroyuki Matsueda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazole derivatives and diabetic medicine containing them
    Patent number: 6815428
    Abstract: The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: November 9, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Koji Ohsumi, Takashi Umemura, Hiroyuki Matsueda, Toshihiro Hatanaka, Akiko Onuki, Katsumi Maezono, Yoko Kageyama, Nobuo Kondo
  • Process for preparing aminostilbene derivatives
    Publication number: 20040176642
    Abstract: The present invention relates to a novel process for preparing an aminostilbene derivative, which is important as an active component of anticancer drugs or an intermediate for preparation thereof, as well as methods of producing the same.
    Type: Application
    Filed: December 22, 2003
    Publication date: September 9, 2004
    Applicant: AJINOMOTO CO. INC
    Inventors: Takashi Yamamoto, Hiroyuki Matsueda, Masaki Naito, Isao Arai, Masanobu Yatagai
  • Stilbene derivative crystal and method for producing the same
    Patent number: 6784315
    Abstract: A Type IV crystal of (Z)-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)vinyl]phenyl]-L-serinamide hydrochloride, which can be produced by crystallization using a solvent containing water at 2% by weight at the maximum and which has a X ray powder diffraction pattern containing peaks at least at 13.4°, 18.7°, 19.4°, and 22.5° (2&thgr;), is provided. This compound is useful as an effective ingredient for a carcinostatic agent. The crystal of the present invention has excellent properties desirable from the standpoint of the production of medicinal products, i.e., reduced water adsorption and extremely high stability to water. Also provided are a method for producing the Type IV crystal thereof and a method for use of the crystal.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: August 31, 2004
    Assignee: Ajinomoto Co. Inc.
    Inventors: Shinichiro Takahashi, Yoko Sugawara, Hiroyuki Matsueda
  • N-substituted pyrazole-O-glycoside derivatives and therapeutic agent for diabetes containing the same
    Publication number: 20040110936
    Abstract: The present invention relates to pyrazole derivatives represented by the following formulas and analogues thereof, which can be used for a therapeutic agent for diabetes.
    Type: Application
    Filed: October 27, 2003
    Publication date: June 10, 2004
    Applicant: Ajinomoto Co., Inc.
    Inventors: Koji Ohsumi, Hiroyuki Matsueda, Toshihiro Hatanaka, Nozomu Ishida, Yoko Kageyama, Katsumi Maezono, Nobuo Kondo
  • Lactam compounds and pharmaceutical use thereof
    Publication number: 20040048847
    Abstract: An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.
    Type: Application
    Filed: June 2, 2003
    Publication date: March 11, 2004
    Applicant: AJINOMOTO CO. INC
    Inventors: Yukio Iino, Takao Ikenoue, Nobuo Kondo, Hiroyuki Matsueda, Toshihiro Hatanaka, Ryusuke Hirama, Yoko Masuzawa, Fumio Ohta, Akiyo Yamazaki
  • Pyrazole derivatives and diabetic medicine containing them
    Publication number: 20040006025
    Abstract: The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine.
    Type: Application
    Filed: May 2, 2003
    Publication date: January 8, 2004
    Applicant: AJINOMOTO CO. INC
    Inventors: Koji Ohsumi, Takashi Umemura, Hiroyuki Matsueda, Toshihiro Hatanaka, Akiko Onuki, Katsumi Maezono, Yoko Kageyama, Nobuo Kondo
  • Novel stilbene derivative crystal and method for producing the same
    Publication number: 20030065035
    Abstract: A Type IV crystal of (Z)-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)vinyl]phenyl]-L-serinamide hydrochloride, which can be produced by crystallization using a solvent containing water at 2% by weight at the maximum and which has a X ray powder diffraction pattern containing peaks at least at 13.4°, 18.7°, 19.4°, and 22.5° (2&thgr;), is provided. This compound is useful as an effective ingredient for a carcinostatic agent. The crystal of the present invention has excellent properties desirable from the standpoint of the production of medicinal products, i.e., reduced water adsorption and extremely high stability to water. Also provided are a method for producing the Type IV crystal thereof and a method for use of the crystal.
    Type: Application
    Filed: September 16, 2002
    Publication date: April 3, 2003
    Applicant: AJINOMOTO CO. INC
    Inventors: Shinichiro Takahashi, Yoko Sugawara, Hiroyuki Matsueda
  • Dihydropyridine derivatives
    Publication number: 20020147222
    Abstract: Compounds having a selective N-type calcium channel antagonistic activity are provided.
    Type: Application
    Filed: December 20, 2001
    Publication date: October 10, 2002
    Applicant: AJINOMOTO CO. INC
    Inventors: Chika Nakanishi, Yoko Masuzawa, Masako Hagihara, Takashi Yamamoto, Hiroyuki Matsueda, Seiji Ohno, Seiji Niwa, Morikazu Kito, Akira Takahara, Yukitsugu Ono, Tomoko Takeda, Yuki Kajigaya, Hajime Koganei
  • Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester
    Patent number: 6258975
    Abstract: Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid. The 2-acyloxy-4-oxo-4-arylbutyric acid is converted to an optically active 2-acyloxy-4-arylbutyric acid through catalytic reduction. The 2-acyloxy-4-arylbutyric acid is hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid. The 2-hydroxy-4-arylbutyric acid is reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: July 10, 2001
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masahiko Kurauchi, Yoshimasa Hagiwara, Hiroyuki Matsueda, Takashi Nakano, Kunisuke Izawa
  • Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester
    Patent number: 6087526
    Abstract: Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid. The 2-acyloxy-4-oxo-4-arylbutyric acid is converted to an optically active 2-acyloxy-4-arylbutyric acid through catalytic reduction. The 2-acyloxy-4-arylbutyric acid is hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid. The 2-hydroxy-4-arylbutyric acid is reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: July 11, 2000
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masahiko Kurauchi, Yoshimasa Hagiwara, Hiroyuki Matsueda, Takashi Nakano, Kunisuke Izawa
  • Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester
    Patent number: 5959139
    Abstract: Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid. The 2-acyloxy-4-oxo-4-arylbutyric acid is converted to an optically active 2-acyloxy-4-arylbutyric acid through catalytic reduction. The 2-acyloxy-4-arylbutyric acid is hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid. The 2-hydroxy-4-arylbutyric acid is reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: September 28, 1999
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masahiko Kurauchi, Yoshimasa Hagiwara, Hiroyuki Matsueda, Takashi Nakano, Kunisuke Izawa