Patents by Inventor Hiroyuki Miki

Hiroyuki Miki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092924
    Abstract: The present invention provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles. The present invention also provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles, the antibody having a reduced effect on bile acid transport by NTCP.
    Type: Application
    Filed: October 7, 2020
    Publication date: March 21, 2024
    Inventors: Toshitada TAKEMORI, Akiko SUGIMOTO, Michishige HARADA, Mikako SHIROUZU, Takehisa MATSUMOTO, Tomomi SOMEYA, Hiroyuki OSADA, Yushi FUTAMURA, Kunitada SHIMOTOHNO, Hironori NISHITSUJI, Kazuaki CHAYAMA, Daiki MIKI
  • Patent number: 8302408
    Abstract: In a temperature control device for liquid medicines provided with a flow path block having flow paths for liquid medicines at both of front and back surfaces, heat-transmitting plates respectively disposed at both of the front and back surfaces of the flow path block in a manner so as to face the flow paths, and thermo-modules for performing a cooling operation or a heating operation on the liquid medicines that flows through the flow path via the heat-transmitting plates, respectively, at least one ridge of mountain-shaped sealing projection portion surrounding a periphery of the flow path are integrally formed with the flow path block at sealing surfaces respectively surrounding the flow paths at both of the front and back surfaces of the flow path block, and the heat-transmitting plates are fixed to the flow path block in a state of pressure-contacting the sealing projection portion.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: November 6, 2012
    Assignee: SMC Corporation
    Inventor: Hiroyuki Miki
  • Publication number: 20080236805
    Abstract: In a temperature control device for liquid medicines provided with a flow path block having flow paths for liquid medicines at both of front and back surfaces, heat-transmitting plates respectively disposed at both of the front and back surfaces of the flow path block in a manner so as to face the flow paths, and thermo-modules for performing a cooling operation or a heating operation on the liquid medicines that flows through the flow path via the heat-transmitting plates, respectively, at least one ridge of mountain-shaped sealing projection portion surrounding a periphery of the flow path are integrally formed with the flow path block at sealing surfaces respectively surrounding the flow paths at both of the front and back surfaces of the flow path block, and the heat-transmitting plates are fixed to the flow path block in a state of pressure-contacting the sealing projection portion.
    Type: Application
    Filed: March 20, 2008
    Publication date: October 2, 2008
    Applicant: SMC Corporation
    Inventor: Hiroyuki Miki
  • Patent number: 6347661
    Abstract: In order to provide a cooling/heating apparatus for a semiconductor processing liquid being highly resistant to corrosive chemicals and free from elution of harmful impurities, a heat exchanging substrate 3 is formed by heat-depositing a fluorine-contained resin sheet 3B to a processing liquid contact surface of a graphite substrate 3A.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: February 19, 2002
    Assignee: SMC Corporation
    Inventor: Hiroyuki Miki
  • Publication number: 20010052409
    Abstract: In order to provide a cooling/heating apparatus for a semiconductor processing liquid being highly resistant to corrosive chemicals and free from elution of harmful impurities, a heat exchanging substrate 3 is formed by heat-depositing a fluorine-contained resin sheet 3B to a processing liquid contact surface of a graphite substrate 3A.
    Type: Application
    Filed: April 19, 1999
    Publication date: December 20, 2001
    Inventor: HIROYUKI MIKI
  • Patent number: 6071090
    Abstract: A diaphragm-type double-acting process pump has a reduced number of members to be assembled to a center plate and also a reduced number of hermetically sealed portions. A space defined by the center plate, together with a side cover and a side body, which are provided on both sides, respectively, of the center plate, is divided by two diaphragms into left and right driving chambers inside the diaphragms and left and right pump chambers outside the diaphragms. The left and right pump chambers are communicated with a suction opening through check valves and also communicated with a discharge opening through check valves. The center plate is fitted in a recess formed in the side body, and the side cover is brought into contact with both the side body and the center plate to clamp the center plate by the side cover and the side body.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: June 6, 2000
    Assignee: SMC Corporation
    Inventors: Hiroyuki Miki, Tsuyoshi Kagami, Yoshihiro Shono
  • Patent number: 5786100
    Abstract: A coated paper prepared by coating an original paper with a paper-coating composition is provided containing a pigment and a copolymer latex having a gel content of 10% by weight or more obtained by polymerizing,(a) 20-65% by weight of a conjugated diene compound,(b) 0.1 to 10% by weight of an ethylenically unsaturated carboxylic acid, and(c) 33-79.5% by weight of at least one ethylenically unsaturated compound other than said components (a) and (b),(d) in the presence of 0.1 to 10 parts by weight of .alpha.-methylstyrene dimer, per 100 parts by weight of a total of components (a), (b) and (c).
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: July 28, 1998
    Assignee: Japan Synthetic Rubber Co., Ltd.
    Inventors: Katsuhiko Tsuruoka, Shozo Nishida, Masafumi Wakamori, Takemitsu Tanaka, Masaaki Yada, Osamu Ishikawa, Hiroyuki Miki
  • Patent number: 5637644
    Abstract: A process is provided for producing a copolymer latex having a gel content of 10-98% by weight, involving emulsion polymerizing:(a) 20-65% by weight of a conjugated diene compound;(b) 0.1-10% by weight of a combination of an ethylenically unsaturated monocarboxylic acid with an ethylenically unsaturated dicarboxylic acid; and(c) 33-79.5% by weight of at least one ethylenically unsaturated compound other than the components (a) and (b),in the presence of (d) 0.1 to 10 parts by weight of an .alpha.-methylstyrene dimer, per 100 parts by weight of a total of components (a), (b) and (c).
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: June 10, 1997
    Assignee: Japan Synthetic Rubber Co., Ltd.
    Inventors: Katsuhiko Tsuruoka, Shozo Nishida, Masafumi Wakamori, Takemitsu Tanaka, Masaaki Yada, Osamu Ishikawa, Hiroyuki Miki
  • Patent number: 5503430
    Abstract: A rollover protection system for a working vehicle including a pair of lower props fixed at lower ends thereof to a chassis, a U-shaped upper cross bar pivotally connected to upper ends of the lower props, and connectors disposed between the lower props and the upper cross bar for selectively permitting the upper cross bar to pivot relative to the lower props. The connectors have a pair of right and left engaging members disposed at the upper ends of the lower props, respectively, a pair of right and left engageable members disposed at lower ends of the upper cross bar, respectively, and control handles for selecting between a first state to engage the engaging members and the engageable members, and a second state to disengage the engaging members and the engageable members.
    Type: Grant
    Filed: April 22, 1994
    Date of Patent: April 2, 1996
    Assignee: Kubota Corporation
    Inventors: Hiroyuki Miki, Tsutomu Toiguchi
  • Patent number: 5444118
    Abstract: A two-stage process for producing a copolymer, comprising emulsion polymerizing (a) a 2-80% by weight of a conjugated diene compound, (b) 0.1-10% by weight of an ethylenically unsaturated carboxylic acid, and (c) 10-97.9% by weight of an ethylenically unsaturated compound other than the components (a) and (b) in the presence of (d) and .alpha.-methylstyrene dimer, wherein in the first stage, 10-50% by weight of the total amount of the components (a), (b) and (c) are added and polymerized at 70.degree.-80.degree. C. for 2-6 hours after the addition of the monomer, and after said first stage, 50-90% by weight of the total amount of the components (a), (b) and (c) are continuously fed and polymerized in a second stage.
    Type: Grant
    Filed: March 19, 1993
    Date of Patent: August 22, 1995
    Assignee: Japan Synthetic Rubber Co., Ltd.
    Inventors: Katsuhiko Tsuruoka, Shozo Nishida, Masafumi Wakamori, Takemitsu Tanaka, Masaaki Yada, Osamu Ishikawa, Hiroyuki Miki
  • Patent number: 5385975
    Abstract: Polymer particles including polysiloxane is disclosed. The polymer particles are prepared by condensing at least one organosilane or organosiloxane compound in the presence of organic polymer particles which are prepared from specific monomers and dispersed in an aqueous medium. The polymer particles possess excellent water resistance, weatherability, water repellency, adhesion, and flexing resistance, and thus are useful as water paints, coating agents, carpet packing material, floor polishing agents, cementing medium, and the like.
    Type: Grant
    Filed: December 28, 1992
    Date of Patent: January 31, 1995
    Assignee: Japan Synthetic Rubber Co., Ltd.
    Inventors: Katsuhiro Nakamura, Minoru Kato, Yasuhisa Watanabe, Yasunori Matsubara, Yorinobu Ikeda, Yoshiaki Yonekawa, Hiroyuki Miki, Akio Hiraharu, Nobuyuki Ito, Osamu Kurita, Yasunobu Kaneko, Shouzou Nishida
  • Patent number: 4940275
    Abstract: An apparatus for scanning recording media (a cassette tape deck) with an automatic medium-change mechanism (automatic cassette tape change mechanism) and a novel structure for mounting same in a vehicle are disclosed. The apparatus is installed in the vehicle body, specifically on a floor console located between the left- and right-hand seats and behind the shift lever of the vehicle transmission to leave the forward field of vision clear and to facilitate operation of the cassette tape deck.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: July 10, 1990
    Assignee: Nissan Motor Company, Limited
    Inventors: Hiroyuki Miki, Yasushi Kawakami
  • Patent number: 4696365
    Abstract: A four wheel drive vehicle with dirigible front wheels, comprising a main propelling drive transmission, and a front wheel drive transmission connected to the main transmission. The front wheel drive transmission is switchable between a first four wheel drive mode in which the front wheels and the rear wheels are driven at a substantially equal peripheral speed and a second four wheel drive mode in which the front wheels are driven at a higher peripheral speed than the rear wheels. The front wheel drive transmission includes a piston operable by a hydraulic control system including a control valve mechanically interlocked to a steering section of the vehicle for switching the front wheel drive transmission from the first drive mode to the second drive mode. The piston, which normally is biased toward a position for the first drive mode, is movable against the biasing force to a position for the second drive mode when the front wheels are steered to an angle exceeding a predetermined angle.
    Type: Grant
    Filed: October 30, 1986
    Date of Patent: September 29, 1987
    Assignee: Kubota, Ltd.
    Inventors: Shozo Ishimori, Mikio Ishida, Hiroyuki Miki, Seiichi Ishiizumi, Kazuo Hirata
  • Patent number: 4669565
    Abstract: An agricultural tractor with a driver's cabin, in which the cabin is supported by a safety frame which is in turn supported by an axle case.
    Type: Grant
    Filed: December 14, 1984
    Date of Patent: June 2, 1987
    Assignee: Kubota, Ltd.
    Inventors: Hiroyuki Miki, Yasuo Nakata, Kazuo Hirata, Seiichi Ishiizumi, Genichi Funabashi
  • Patent number: 4609065
    Abstract: A wheel drive structure for an agricultural tractor comprising a drive case housing a differential mechanism and reduction mechanisms to transmit power from said differential mechanism to wheels. The drive case comprises first and second case portions and said first case portion is made of a structural steel pipe.
    Type: Grant
    Filed: January 16, 1985
    Date of Patent: September 2, 1986
    Assignee: Kubota, Ltd.
    Inventors: Hajime Shikiya, Hiroyuki Miki, Yasuo Nakata, Kazuo Hirata, Seiichi Ishiizumi
  • Patent number: 4574910
    Abstract: A transmission for agricultural tractors in which a front wheel speed increasing transmission part (12) is disposed forwardly of a main transmission part (8). An input shaft (13) and an output shaft (15) of the speed increasing transmission part (12) are arranged coaxial with a front wheel drive output shaft (14a) of the main transmission part (8).
    Type: Grant
    Filed: December 12, 1984
    Date of Patent: March 11, 1986
    Assignee: Kubota, Ltd.
    Inventors: Hiroyuki Miki, Mikio Kinoshita, Tetsu Fukui
  • Patent number: D306301
    Type: Grant
    Filed: March 27, 1987
    Date of Patent: February 27, 1990
    Assignee: Kubota, Ltd.
    Inventors: Genichi Funabashi, Hiroyuki Miki
  • Patent number: D306450
    Type: Grant
    Filed: February 20, 1987
    Date of Patent: March 6, 1990
    Assignee: Kubota, Ltd.
    Inventors: Genichi Funabashi, Hiroyuki Miki
  • Patent number: D321517
    Type: Grant
    Filed: April 28, 1989
    Date of Patent: November 12, 1991
    Assignee: Kubota, Ltd.
    Inventors: Hisato Katoh, Hiroyuki Miki
  • Patent number: D378755
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: April 8, 1997
    Assignee: Kubota Corporation
    Inventors: Hisato Kato, Hiroyuki Miki