Patents by Inventor Hiroyuki Miura

Hiroyuki Miura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11458107
    Abstract: The present invention relates generally to compositions and methods comprising abiotic, synthetic polymers with affinity and specificity to proteins. The synthetic polymers are an improvement over biological agents by providing a simpler, less expensive, and customizable platform for binding to proteins. In one embodiment, the compositions and methods relate to synthetic polymers with affinity and specificity to vascular endothelial growth factor (VEGF). In one embodiment, the compositions are useful for treating diseases and disorders related to the overexpression of VEGF. In one embodiment, the compositions are useful for treating cancer. In one embodiment, the compositions are useful for detecting VEGF levels from biological samples. In one embodiment, the compositions are useful for detecting overexpression of VEGF from biological samples. In one embodiment, the compositions are used to diagnose cancer.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: October 4, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kenneth J. Shea, Hiroyuki Koide, Yoshiko Miura, Yu Hoshino, Yuri Nishimura, Naoto Oku
  • Publication number: 20220310795
    Abstract: A method for manufacturing a silicon carbide epitaxial substrate which has a first surface which is a (000-1) C-face, a silicon carbide epitaxial layer located on the first surface of the silicon carbide substrate, and a line-shaped surface defect density on a top surface of the silicon carbide epitaxial layer is less than 1.0 cm?2 and a stacking fault density is less than 1.2 cm?2.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 29, 2022
    Inventors: Tsuyoshi MIURA, Hodaka ICHIKAWA, Naoya KIMURA, Hiroyuki OKUDA, Taisuke HIROOKA
  • Publication number: 20220302102
    Abstract: A modeling method of shape-approximating a shape measurement target provided in a structure having a stack structure by a boundary line, and a standard deviation is provided as a tolerance for a measurement value of the shape measurement target, and a calculation boundary line is arranged to converge within the tolerance, and thereby, a shape of the shape measurement target is expressed.
    Type: Application
    Filed: August 16, 2021
    Publication date: September 22, 2022
    Applicant: Kioxia Corporation
    Inventors: Shimpei MIURA, Hiroshi TSUKADA, Kiminori YOSHINO, Hiroyuki TANIZAKI
  • Publication number: 20220285143
    Abstract: An MT-TOFMS which is one mode of the present invention includes: a linear ion trap (2) configured to temporarily hold ions to be analyzed, and to eject the ions through an ion ejection opening (211) having a shape elongated in one direction; a loop flight section (3) configured to form a loop path (P) capable of making ions repeatedly fly; and a slit part (5) located on an ion path in which the ions ejected from the linear ion trap (2) travel until the ions are introduced into the loop path, the slit part configured to block a portion of the ions in a longitudinal direction of the ion ejection opening (211).
    Type: Application
    Filed: August 11, 2020
    Publication date: September 8, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Yoshihiro UENO, Ryugo MAEDA, Yusuke TATEISHI, Hiroyuki MIURA
  • Publication number: 20220278141
    Abstract: A photodetector according to an embodiment of the present disclosure including a plurality of photoelectric conversion sections that is provided to a semiconductor substrate. The photoelectric conversion sections each include a first region of a first electrical conduction type that is provided on a first surface side of the semiconductor substrate, a second region of a second electrical conduction type that is provided on a second surface side of the semiconductor substrate opposite to the first surface, a third region of a third electrical conduction type that is provided in a region between the first region and the second region of the semiconductor substrate, a first electrode that extends from the second surface in a thickness direction of the semiconductor substrate, a pixel separation layer having an insulation property, and a second electrode that is electrically coupled to the second region from the second surface side. The third region absorbs incident light.
    Type: Application
    Filed: March 30, 2020
    Publication date: September 1, 2022
    Applicant: SONY SEMICONDUCTOR SOLUTIONS CORPORATION
    Inventors: Takahiro HAMASAKI, Hiroyuki TAKASHINO, Koji NAGAHIRO, Hiroyuki OHRI, Satoe MIYATA, Takahiro MIURA, Hisao YOSHIMURA
  • Patent number: 11417575
    Abstract: A board in an aspect of the present invention includes a substrate, a first film, a first layer, and a second film. The substrate has a first elastic modulus. The first film is at an upper surface of the substrate. The first layer is at a lower surface of the substrate. The first layer has a second elastic modulus lower than the first elastic modulus and has a first thermal expansion coefficient. The second film is at a lower surface of the first layer. The second film includes the same material as the first film and has a second thermal expansion coefficient lower than the first thermal expansion coefficient.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: August 16, 2022
    Assignee: KYOCERA CORPORATION
    Inventors: Takayuki Kimura, Hisaki Masuda, Takayuki Ohyama, Yuko Tanaka, Yoshihiro Uemura, Hiroyuki Miura
  • Patent number: 11390948
    Abstract: A film forming apparatus for performing a predetermine film forming process on a substrate mounted on an upper surface of a rotary table installed within a process vessel while rotating the rotary table and heating the substrate by a heating part, includes: a contact type first temperature measuring part configured to measure a temperature of the heating part; a non-contact type second temperature measuring part configured to measure a temperature of the substrate; and a control part configured to control a power supplied to the heating part based on at least one among a first measurement value measured by the first temperature measuring part and a second measurement value measured by the second temperature measuring part. The control part changes a method for controlling the power when the predetermined film forming process is performed on the substrate and when the substrate is loaded into or unloaded from the process vessel.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: July 19, 2022
    Assignee: TOKYO ELECTRON LIMITED
    Inventors: Masato Yonezawa, Shigehiro Miura, Hiroyuki Akama, Koji Yoshii
  • Publication number: 20220189758
    Abstract: Provided is a time-of-flight mass spectrometer including: a loop-orbit defining electrode (21) including an outer electrode (211) and inner electrode (212) located on the outside and inside of a loop orbit, respectively; an ion inlet (22); an ion outlet (23) provided in either the outer or inner electrode; a loop-flight voltage applier (28) configured to apply loop-flight voltages to the outer and inner electrodes, respectively; a set of deflecting electrodes (24) facing each other across a section of an n-th loop orbit, where n is a predetermined number, the deflecting electrodes including a first portion (241) which faces the n-th loop orbit and a second portion (242) which includes other portions; and a voltage applier (29) configured to apply deflecting voltages to the first portion so as to reverse the drifting direction of the ions flying in the n-th loop orbit, and a voltage to the second portion so as to create the loop-flight electric field.
    Type: Application
    Filed: September 3, 2021
    Publication date: June 16, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Yusuke TATEISHI, Hiroyuki MIURA, Hideaki IZUMI
  • Publication number: 20220059329
    Abstract: Provided is a method for mass spectrometry in which ions to be analyzed are made to come in contact with a cooling gas in a cooling section, such as an ion trap 2, configured to perform the cooling of ions, and kinetic energy is subsequently imparted to the ions so as to introduce the ions into a flight space of a multi-turn time-of-flight mass separator 30 or similar device for separating ions according to their mass-to-charge ratios. According to the present invention, when a known or estimated number of charges of an ion to be analyzed is high, the amount of supply of the cooling gas to the cooling section is set to a lower level than when the number of charges is low. This operation improves the detection sensitivity for ions having large molecular weights and high numbers of charges.
    Type: Application
    Filed: May 25, 2021
    Publication date: February 24, 2022
    Applicant: SHIMADZU CORPORATION
    Inventors: Hiroyuki MIURA, Hideaki IZUMI
  • Publication number: 20210265226
    Abstract: Aboard in an aspect of the present invention includes a substrate, a first film, a first layer, and a second film. The substrate has a first elastic modulus. The first film is at an upper surface of the substrate. The first layer is at a lower surface of the substrate. The first layer has a second elastic modulus lower than the first elastic modulus and has a first thermal expansion coefficient. The second film is at a lower surface of the first layer. The second film includes the same material as the first film and has a second thermal expansion coefficient lower than the first thermal expansion coefficient.
    Type: Application
    Filed: June 27, 2019
    Publication date: August 26, 2021
    Applicant: KYOCERA Corporation
    Inventors: Takayuki KIMURA, Hisaki MASUDA, Takayuki OHYAMA, Yuko TANAKA, Yoshihiro UEMURA, Hiroyuki MIURA
  • Patent number: 11094522
    Abstract: To compensate for the distortion of the loop-flight electric field with a higher level of accuracy, a multiturn time-of-flight mass spectrometer 1 includes: a main electrode 21 configured to generate, within a predetermined loop-flight space, a loop-flight electric field which is an electric field that makes an ion fly in a loop orbit multiple times, the main electrode having an opening 24 or 25 through which ions are introduced into or extracted from the loop-flight space; a compensating-electrode attachment part 23 made of an insulating material and fixed to the main electrode; and a compensating electrode 22 configured to compensate for a distortion of the loop-flight electric field which occurs in the vicinity of the opening, the compensating electrode being fixed to the compensating-electrode attachment part directly or via a substrate 221 and located in the vicinity of the opening.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: August 17, 2021
    Assignee: SHIMADZU CORPORATION
    Inventors: Hiroyuki Miura, Hideaki Izumi
  • Publication number: 20210199539
    Abstract: A test device includes an input side drive part that drives a steering shaft of a steering device, a control part that controls the input side drive part, and a position detecting part that detects an angular position of the steering shaft. The control part restricts a maximum value of a torque of the steering shaft when the angular position reaches an end abutment position. The control part also controls driving of the steering shaft by a position control in which the angular position is used as a controlled variable and a torque control in which the torque is used as a controlled variable. The control part performs the position control when the angular position is outside a first angular range including the end-abutment position and switches the driving of the steering shaft from the position control to the torque control when the angular position reaches within the first angular range.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 1, 2021
    Applicant: KOKUSAI KEISOKUKI KABUSHIKI KAISHA
    Inventors: Sigeru MATSUMOTO, Hiroshi MIYASHITA, Kazuyoshi TASHIRO, Kazuhiro MURAUCHI, Hiroyuki MIURA, Akihiro YONEKAWA, Kazuki SHINOHARA
  • Patent number: 11014868
    Abstract: A method for producing acetic acid includes subjecting an acetic acid solution to an acetic anhydride decreasing treatment. The acetic acid solution is present typically in, or downstream from, a distillation column (5) of acetic acid production equipment (X), includes acetic acid in a concentration of 90 mass percent or more, acetic anhydride, and water, and is in such a state that an equilibrium concentration of acetic anhydride is higher than an acetic anhydride concentration. The acetic anhydride decreasing treatment includes at least one of water concentration increasing and temperature lowering so as to bring the acetic acid solution into such a state that the equilibrium concentration of acetic anhydride is lower than the acetic anhydride concentration. The acetic acid production method is suitable for yielding a high-purity acetic acid product.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 25, 2021
    Assignee: DAICEL CORPORATION
    Inventors: Masahiko Shimizu, Ryuji Saito, Hiroyuki Miura
  • Publication number: 20210111015
    Abstract: To compensate for the distortion of the loop-flight electric field with a higher level of accuracy, a multiturn time-of-flight mass spectrometer 1 includes: a main electrode 21 configured to generate, within a predetermined loop-flight space, a loop-flight electric field which is an electric field that makes an ion fly in a loop orbit multiple times, the main electrode having an opening 24 or 25 through which ions are introduced into or extracted from the loop-flight space; a compensating-electrode attachment part 23 made of an insulating material and fixed to the main electrode; and a compensating electrode 22 configured to compensate for a distortion of the loop-flight electric field which occurs in the vicinity of the opening, the compensating electrode being fixed to the compensating-electrode attachment part directly or via a substrate 221 and located in the vicinity of the opening.
    Type: Application
    Filed: October 1, 2020
    Publication date: April 15, 2021
    Applicant: SHIMADZU CORPORATION
    Inventors: Hiroyuki MIURA, Hideaki Izumi
  • Patent number: 10894759
    Abstract: A process for stably and safely producing acetic acid without increasing an internal pressure of a distillation column is provided. The process comprises (1) a carbonylation reaction step for allowing methanol to react with carbon monoxide; (2) a flash step for separating the reaction mixture into a volatile phase and a less-volatile phase; (3) a first distillation step for separating the volatile phase into a first overhead and a crude acetic acid stream rich in acetic acid; and (4) a separation step for separating at least acetaldehyde from the first overhead.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: January 19, 2021
    Assignee: DAICEL CORPORATION
    Inventors: Hiroyuki Miura, Yoshihisa Mizutani
  • Patent number: 10661196
    Abstract: A process for separating or removing permanganate reducing compounds (PRC's) from a first mixture containing at least one PRC, methyl iodide, and water comprises the steps of: feeding the first mixture to a feed port of a distillation column, and distilling and separating the first mixture into an upper stream and a lower stream, wherein the distillation of the first mixture forms a second mixture at an upper position than the feed port, and the process further comprises the steps of: withdrawing the second mixture as the upper stream, and withdrawing the lower stream from a lower position than the feed port.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 26, 2020
    Assignee: DAICEL CORPORATION
    Inventors: Masahiko Shimizu, Yoshihisa Mizutani, Hiroyuki Miura
  • Patent number: 10633322
    Abstract: A process for producing acetic acid comprises a process comprising: (1) carbonylating methanol; (2) separating the reaction mixture into a volatile phase and a less-volatile phase; (3) distilling the volatile phase to forma first overhead rich in a lower boiling component, and an acetic acid stream rich in acetic acid; and at least one step group selected from the group consisting of the following sections (4), (9), and (15): (4) a section for separating impurities from the acetic acid stream to give purified acetic acid, (9) a section for separating the first overhead into a stream rich in acetaldehyde and a stream rich in methyl iodide, and (15) a section for absorption-treating an off-gas from the process with an absorption solvent and forming a carbon monoxide-rich stream and an acetic acid-rich stream.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: April 28, 2020
    Assignee: DAICEL CORPORATION
    Inventors: Masahiko Shimizu, Yoshihisa Mizutani, Hiroyuki Miura
  • Patent number: 10562836
    Abstract: A process for producing acetic acid while efficiently separating permanganate reducing compounds (PRC's) and methyl iodide is provided. PRC's are separated or removed from a mixed composition (3A) containing PRC's and methyl iodide by distilling the mixed composition in a distillation step (5) to form an overhead stream (5A), a side-cut stream (5B), and a lower stream (5C). In a distillation column of the distillation step (5), an extractant (e.g., water) extracting PRC's preferentially to methyl iodide is added to a concentration zone in which PRC's and methyl iodide are concentrated, and an extraction mixture falling from the concentration zone is withdrawn as the side-cut stream (5B).
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: February 18, 2020
    Assignee: DAICEL CORPORATION
    Inventors: Masahiko Shimizu, Hiroyuki Miura, Yoshihisa Mizutani
  • Patent number: 10541125
    Abstract: A microchannel plate (MCP) 41 in an ion detection section 4 multiplies electrons. An anode 42 detects those electrons and produces a current signal. An amplifier 44 converts this signal into a voltage signal. A low-pass filter 5A acting as a smoothing section 5 is located at the output end of the amplifier 44. A waveform-shaping time adjuster 6 adjusts the time constant of the low-pass filter 5A beforehand according to the response time of the MCP 41, mass-to-charge ratio of an ion species to be subjected to the measurement, and duration of the spread of the ion species which depends on device-specific parameters. A plurality of peaks which sequentially appear in the detection signal corresponding to one ion species are thereby smoothed into a single broad peak. Thus, the distinguishability between signal waves and noise components is improved.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: January 21, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Hiroyuki Miura, Hideaki Izumi, Kiyoshi Ogawa
  • Patent number: RE48855
    Abstract: A production process of acetic acid according to the present invention inhibits concentration of hydrogen iodide and improves a liquid-liquid separation of an overhead from a distillation column. Acetic acid is produced by distilling a mixture containing hydrogen iodide, water, acetic acid and methyl acetate in a first distillation column (3) to form an overhead and a side cut stream or bottom stream containing acetic acid, cooling and condensing the overhead in a condenser (C3) to form separated upper and lower phases in a decanter (4). According to this process, a zone having a high water concentration is formed in the distillation column above the feed position of the mixture by feeding a mixture having a water concentration of not less than an effective amount to not more than 5% by weight (e.g., 0.5 to 4.5% by weight) and a methyl acetate concentration of 0.5 to 9% by weight (e.g., 0.5 to 8% by weight) as the mixture to the distillation column and distilling the mixture.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: December 21, 2021
    Assignee: DAICEL CORPORATION
    Inventors: Masahiko Shimizu, Hiroyuki Miura, Takashi Ueno, Hidehiko Nakajima