Patents by Inventor Hiroyuki Nunoi

Hiroyuki Nunoi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and reagent for testing for multiple organ failure in SIRS by cytochrome C measurement
    Patent number: 7138239
    Abstract: A method for testing for multiple organ failure in SIRS, which comprises determining cytochrome C in body fluid and using the determined result as an index of the multiple organ failure, and a reagent for testing for multiple organ failure in SIRS, which comprises a reagent for determination of cytochrome C in body fluid.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: November 21, 2006
    Assignee: Eisai Co., Ltd.
    Inventors: Fumio Endo, Naoto Adachi, Hiroyuki Nunoi, Keisuke Watanabe
  • Method and reagent for detecting cell death
    Publication number: 20060183176
    Abstract: A method for detecting cell death, which comprises determining cytochrome C in body fluid and detecting cell death based on a quantified value, as well as a method for determining cytochrome C in body fluid by a sandwich method and a reagent for measuring cytochrome C for determination cytochrome C in body fluid by a sandwich method, which comprises an antibody directed to cytochrome C as an ingredient.
    Type: Application
    Filed: April 12, 2006
    Publication date: August 17, 2006
    Inventors: Fumio Endo, Naoto Adachi, Hiroyuki Nunoi, Keisuke Watanabe
  • Method of detecting cell death and detection reagent
    Patent number: 7070924
    Abstract: A method for detecting cell death, which comprises determining cytochrome C in body fluid and detecting cell death based on a quantified value, as well as a method for determining cytochrome C in body fluid by a sandwich method and a reagent for measuring cytochrome C for determination cytochrome C in body fluid by a sandwich method, which comprises an antibody directed to cytochrome C as an ingredient.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: July 4, 2006
    Assignee: EISAI Co., Ltd.
    Inventors: Fumio Endo, Naoto Adachi, Hiroyuki Nunoi, Keisuke Watanabe
  • Method and reagent for testing for multiple organ failure in sirs by cytochrome C measurement
    Publication number: 20020192712
    Abstract: A method for testing for multiple organ failure in SIRS, which comprises determining cytochrome C in body fluid and using the determined result as an index of the multiple organ failure, and a reagent for testing for multiple organ failure in SIRS, which comprises a reagent for determination of cytochrome C in body fluid.
    Type: Application
    Filed: May 6, 2002
    Publication date: December 19, 2002
    Inventors: Fumio Endo, Naoto Adachi, Hiroyuki Nunoi, Keisuke Watanabe
  • Peptide derivatives of cytochrome b.sub.558 and their use as medicaments
    Patent number: 5585346
    Abstract: Peptide derivatives with inhibitory activity on the enzyme systems involved in the oxidative burst of human phagocytic cells comprise a certain sequence of a number of carboxyl-terminal amino acids of human cytochrome b.sub.558. The derivatives may be used in medicaments for the treatment of inflammatory diseases.
    Type: Grant
    Filed: March 31, 1989
    Date of Patent: December 17, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Harry L. Malech, Karen J. Lomax, Daniel Rotrosen, Hiroyuki Nunoi