Patents by Inventor Hiroyuki Ohno
Hiroyuki Ohno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050261371Abstract: Formula (I) compounds: wherein R1 is alkyl substituted by fluorine(s); R2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR3R4, in which R3, R4 is (i) hydrogen, (ii) alkyl, (iii) phenyl, (iv) phenyl substituted by alkoxy or carboxyl, (v) heterocyclic ring containing nitrogen atom, (vi) alkyl substituted by phenyl, phenyl subsituted by alkoxy or carboxyl, heterocyclic ring containing nitrogen atom, (vii) the nitrogen bonded to R3 and R4, taken together is a saturated heterocyclic ring or amino acid residue; and non-toxic salts and acid addition salts thereof.Type: ApplicationFiled: July 29, 2005Publication date: November 24, 2005Inventors: Shuichi Ohuchida, Kazuo Kishimoto, Narito Tateishi, Hiroyuki Ohno
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Publication number: 20050077498Abstract: A composite of an organic monomer compound and an organic or inorganic salt, wherein the organic monomer compound comprises an ion-complexing moiety, a mesogen moiety that expresses a liquid crystalline phase and a polymerizable moiety in its molecular structure, is polymerized at the polymerizable moiety of the organic monomer compound, thereby forming an anisotropic ion-conductive polymeric liquid crystalline composite as a novel material having high ion conductivity characteristic of polymeric electrolytes, anisotropy due to orientation of a liquid crystal, and self-supporting properties characteristic of polymeric compounds.Type: ApplicationFiled: January 22, 2003Publication date: April 14, 2005Inventors: Takashi Kato, Kenji Kishimoto, Hiroyuki Ohno
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Publication number: 20040169158Abstract: A novel liquid-crystalline ionic conductor, which is useful in the electric, electronic, chemical and bioengineering fields, as an anisotropic reaction solvent, ionic conductor, electric field-responsible conductor or the like, and a method for producing the same, is provided. The liquid-crystalline ionic conductor is obtained by mixing an organic molten salt with a liquid-crystalline organic molecule or a liquid-crystalline inorganic molecule, which comprises a moiety miscible to the organic molten salt and a moiety that shows liquid-crystalline orientation, thereby forming a liquid-crystalline ionic conductor, wherein the organic molten salt is assembled to the liquid-crystalline molecule.Type: ApplicationFiled: December 29, 2003Publication date: September 2, 2004Inventors: Takashi Kato, Kiyoshi Kanie, Masafumi Yoshio, Hiroyuki Ohno, Masahiro Yoshizawa
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Patent number: 6778816Abstract: A communication terminal device comprising: a plurality of demodulation circuits that correspond to the received signals of the same frequency band, said signals being modulated in the respectively different modulation modes, a decision circuit for determining the modulation mode of each of the received signals whose reception level is greater than a predetermined level, on the basis of the frequency component of the received signal, and a control circuit, which puts one of the demodulation circuits that corresponds to the modulation mode of said received signal to an active state on the basis of the decision made by said decision circuit, and simultaneously puts said decision circuit to an inactive state. Due to this construction, by use of this communication terminal device capable of communicating, in various communication modes corresponding to a plurality of communication system, the total power consumption can be greatly reduced.Type: GrantFiled: May 25, 2000Date of Patent: August 17, 2004Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Hiroyuki Ohno
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Publication number: 20030170865Abstract: The present invention is related to a novel protein p140 polypeptide which is a key protein involved in the signal transmission system of insulin; method for preparation of it; DNA encoding the said polypeptide; vector derived the said DNA; host cells transformed the said vector; antibody of the said polypeptide; pharmaceutical composition containing the said peptide or antibody; method for the prevention and/or treatment of diabetes, which is characterized by tyrosine phosphorylation of the said protein p140; agent for the prevention and/or treatment for the currently said the prevention and/or treatment method; agent for the prevention and/or treatment of diabetes, which is characterized by containing a compound which can tyrosine phosphorylation of protein p140, as active ingredient and the screening methods of the said prevention and/or treatment agent.Type: ApplicationFiled: July 3, 2002Publication date: September 11, 2003Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Hisao Tajima, Koichiro Kitagawa, Hiroyuki Ohno
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Publication number: 20030096802Abstract: The compound of the formula (I) 1Type: ApplicationFiled: July 15, 2002Publication date: May 22, 2003Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Shuichi Ohuchida, Kazuo Kishimoto, Narito Tateishi, Hiroyuki Ohno
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Publication number: 20030028537Abstract: Herein disclosed a relay server comprising: protocol conversion means for receiving an input data signal in an input-side protocol transmitted by an output entity, converting the input data signal in the input-side communications protocol into an output data signal in an output-side communications protocol applicable to an input entity, and transmitting the output data signal in the output-side communications protocol to the input entity; and control means for receiving terminal protocol information indicative of the output-side communications protocol applicable to the input entity from the input entity and controlling the protocol conversion means in response to the terminal protocol information, thereby making it possible for an output entity and an input entity to receive and transmit data signals between them regardless of whether the output entity and the input entity share the same communications protocol or not.Type: ApplicationFiled: July 24, 2002Publication date: February 6, 2003Inventors: Manabu Nakamura, Kazuya Matsumoto, Hiroyuki Ohno, Motohiro Misawa
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Patent number: 6451796Abstract: The compound of the formula (I): wherein all the symbols are meaning the same as descriptions of the specification; and salts thereof. The compounds of the formula (I) have inhibitory activity of adhesion molecules expression, and are useful for prevention and/or treatment of inflammation, rheumatoid arthritis, allergies, asthma, atopic dermatitis, psoriasis, suppression of ischemia reperfusion injury, nephritis, hepatitis, multiple sclerosis, ulcerative colitis, adult respiratory distress syndrome (ARDS), suppression of transplant rejection, sepsis, diabetes, autoimmune diseases, tumor metastasis, arteriosclerosis and AIDS.Type: GrantFiled: May 10, 2000Date of Patent: September 17, 2002Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Kaoru Kobayashi, Tadashi Tatsumi, Kiyoyuki Sato, Hiroyuki Ohno
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Publication number: 20020110864Abstract: The present invention is related to novel polypeptide consisting of 205 amino acids which is produced in an endothelial cell line of human umbilical cord vein, a method of producing it, DNA encoding the polypeptide, a vector comprising the DNA, host cells transformed or transfected with the vector, an antibody to the polypeptide and pharmaceutical composition containing the polypeptide or antibody. The polypeptide of the present invention may be useful as itself or secretion type for the prevention of or in treatment of immune diseases caused by adhesion of platelet, many kind of leukocytes and macrophage and disease relating to thrombus formation (e.g. rheumatoid arthritic, allergy, arteriosclerosis, rejection after an internal organ plantation, myocardial infarction, brain infraction or reperfusion failure caused by it, DIC and septicemia etc.), or for screening test of the prevention of and/or in treatment of the above disease.Type: ApplicationFiled: February 25, 2002Publication date: August 15, 2002Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Shiro Shibayama, Atsushi Hirano, Hiroyuki Ohno
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Patent number: 6432913Abstract: The present invention is related to a novel protein p140 polypeptide which is a key protein involved in the signal transmission system of insulin; method for preparation of it; DNA encoding the said polypeptide; vector derived the said DNA; host cells transformed the said vector; antibody of the said polypeptide; pharmaceutical composition containing the said peptide or antibody; method for the prevention and/or treatment of diabetes, which is characterized by tyrosine phosphorylation of the said protein p140; agent for the prevention and/or treatment for the currently said the prevention and/or treatment method; agent for the prevention and/or treatment of diabetes, which is characterized by containing a compound which can tyrosine phosphorylation of protein p140, as active ingredient and the screening methods of the said prevention and/or treatment agent. Tyrosine phosphorylation of protein p140 is an essential step in the induction of hypoglycemia by glucose uptake.Type: GrantFiled: April 26, 2000Date of Patent: August 13, 2002Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Hisao Tajima, Koichiro Kitagawa, Hiroyuki Ohno
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Patent number: 6395857Abstract: A modified organopolysiloxane in which a carboxyl group of a heterocyclic compound having a carboxyl group and containing a nitrogen atom as a heteroatom is combined with an amino group of an amino-modified silicone is used as a gelling agent for low-viscosity silicone oil, which can allow the low-viscosity silicone oil to stably gel without losing the characteristics thereof.Type: GrantFiled: May 23, 2000Date of Patent: May 28, 2002Assignee: Chiba Flour Milling Co. Ltd.Inventors: Takanao Suzuki, Daisuke Tsukioka, Hiroyuki Ohno, Natsue Kawahara
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Patent number: 6376484Abstract: A tetrazole derivatives of formula (I) wherein R1 is H, alkyl, alkoxy, carbocyclic ring, hetero ring, alkyl or alkoxy substituted by carbocyclic ring or hetero ring, etc.; AA1 is bond or AA2 is bond or AA1 and AA2, together, may have the formula (a); Y is the formula (b) (in which Tet ring is tetrazole; Z is alkylene, alkenylene, O, S, SO, SO2, NR26, methylene in alkylene replaced by O, S, —SO—, —SO2— or —NR26—; E is H, alkyl, COOR27 or in which Cyc is carbocyclic ring or hetero ring); a non-toxic salt thereof, an acid addition salt thereof or a hydrate thereof which has a pharmaceutical agents as an active ingredient. The compound of the formula (I) has an inhibitory effect on interleukin-1&bgr; converting enzyme, therefore, they are useful for prevention and/or treatment of various kinds of inflammatory disease.Type: GrantFiled: May 16, 2000Date of Patent: April 23, 2002Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Kazuyuki Ohmoto, Makoto Tanaka, Tohru Miyazaki, Hiroyuki Ohno
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Patent number: 6303320Abstract: The present invention is related to a novel protein p140 polypeptide which is a key protein involved in the signal transmission system of insulin; method for preparation of it; DNA encoding the polypeptide; vector derived with the DNA; host cells transformed with the vector; antibody of the polypeptide; pharmaceutical composition containing the peptide or antibody; method for the prevention and/or treatment of diabetes, which is characterized by tyrosine phosphorylation of the protein p140; agent for the prevention and/or treatment of diabetes, which is characterized by containing a compound which can tyrosine phosphorylate protein p140, as active ingredient and the screening methods of the prevention and/or treatment agent. Tyrosine phosphorylation of protein p140 is an essential step in the induction of hypoglycemia by glucose uptake.Type: GrantFiled: January 8, 1998Date of Patent: October 16, 2001Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Hisao Tajima, Koichiro Kitagawa, Hiroyuki Ohno
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Patent number: 6249276Abstract: A pen-inputted personal information terminal device comprises a dedicated pen incorporating therein an ID code transmitting section for transmitting a specific ID code. When the dedicated pen is accommodated in a pen accommodating section of the main system of the terminal, an ID receiving section receives ID code from the dedicated pen, and a control section authorizes the input, if it is determined that the received ID code matches an ID code stored in a storage section, from a tablet with any other pen. When input from the tablet is executed with the dedicated pen even if the dedicated pen is not accommodated in the pen accommodating section of the main system thereof, the control section determines the ID code, and authorizes the input from the tablet if the inputted ID code matches the previously stored ID code.Type: GrantFiled: August 27, 1997Date of Patent: June 19, 2001Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Hiroyuki Ohno
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Patent number: 6201021Abstract: Formula (I) compounds: wherein R1 is alkyl substituted by fluorine(s); R2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR3R4, in which R3, R4 is (i) hydrogen, (ii) alkyl, (iii) phenyl, (iv) phenyl substituted by alkoxy or carboxyl, (v) heterocyclic ring containing nitrogen atom, (vi) alkyl substituted by phenyl, phenyl subsituted by alkoxy or carboxyl, heterocyclic ring containing nitrogen atom, (vii) the nitrogen bonded to R3 and R4, taken together is a saturated heterocyclic ring or amino acid residue; and non-toxic salts and acid addition salts thereof.Type: GrantFiled: July 23, 1996Date of Patent: March 13, 2001Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Shuichi Ohuchida, Kazuo Kishimoto, Narito Tateishi, Hiroyuki Ohno
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Patent number: 6136834Abstract: A tetrazole derivative of formula (I) ##STR1## wherein R is H, alkyl, alkoxy, carbocyclic ring, alkyl or alkoxy substituted by carbocyclic ring;AA.sup.1 and AA.sup.2 is a bond or ##STR2## and ##STR3## respectively, or AA.sup.1 and AA.sup.2, together, may have the formula (a); ##STR4## and Y is formula (b) ##STR5## wherein the Tet ring is tetrazole; Z is alkylene, alkenylene, O, S, SO, SO.sub.2, NR.sup.26, methylene in alkylene replaced by O, S, --SO--, --SO.sub.2 -- or --NR.sup.26 --; and E is H, alkyl, or COOR.sup.27.Type: GrantFiled: June 29, 1998Date of Patent: October 24, 2000Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Kazuyuki Ohmoto, Makoto Tanaka, Tohru Miyazaki, Hiroyuki Ohno
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Patent number: 6048639Abstract: In a thin type sealed cell utilizing a cell case made of a laminated material, a storage life and reliability of the cell is increased by preventing a sectional surface at an end of the laminated material from being exposed in the cell case, and thereby a leakage of an electrolyte out of the cell and a short circuit in the cell are avoided. This is achieved by disposing a resin layer on the inner surface of the cell case composed of a sheet type laminated material, and covering the sectional surface existing inside the cell case with resin.Type: GrantFiled: January 19, 1999Date of Patent: April 11, 2000Assignee: Sanyo Electric Co., Ltd.Inventors: Tsutomu Sonozaki, Hiroyuki Ohno, Ikuro Nakane, Satoshi Narukawa
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Patent number: 6025457Abstract: Novel molten-salt type polyelectrolytes are disclosed which contain as an essential ingredient a molten salt polymer obtained by reacting an imidazolium derivative, such as a 1,3-dialkylimidazolium halide, 1,2,3-trialkylimidazolium halide, 1-vinyl-3-alkylimidazolium halide, or 1-vinyl-2,3-alkylimidazolium halide, with an acid monomer, a poly(vinylsulfonamide), trifluoromethanesulfonimide, or the like. The electrolytes show high ionic conductivity at room temperature and have excellent stability to temperature fluctuations and excellent mechanical properties.Type: GrantFiled: December 23, 1997Date of Patent: February 15, 2000Assignee: Shikoku Chemicals CorporationInventors: Hiroyuki Ohno, Kaori Ito
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Patent number: 5998410Abstract: A sulfonamide derivatives of formula (I) ##STR1## a non-toxic salts, an acid addition salts or a solvates thereof which has an inhibitory effect on elastase.Type: GrantFiled: February 26, 1998Date of Patent: December 7, 1999Assignee: Ono Pharmaceuticals Co., Ltd.Inventors: Takahiko Nakae, Masashi Kato, Takehito Fujita, Kazuhito Kawabata, Hiroyuki Ohno
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Patent number: 5859243Abstract: Disclosed are amino silicone derivatives having triazinyl groups or pyrimidinyl groups bound to amino groups of amino silicones, their production and use, said silicone derivatives being able to gel silicone oil or to increase the viscosity thereof stably and homogeneously, and therefore being useful as bases for cosmetics, pharmaceutical preparations and industrial materials.Type: GrantFiled: September 15, 1997Date of Patent: January 12, 1999Assignee: Chiba Flour Milling Co., Ltd.Inventors: Hiroyuki Ohno, Natsue Kawahara, Isaburo Amano, Takanao Suzuki, Koji Chiba