Patents by Inventor Hiroyuki Okihana

Hiroyuki Okihana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REPAIR AND TREATMENT OF BONE DEFECT USING AGENT PRODUCED BY CHONDROCYTES CAPABLE OF HYPERTROPHICATION AND SCAFFOLD
    Publication number: 20100297210
    Abstract: The present invention provides a composite material for promoting or inducing osteogenesis in a biological organism. The composite material includes: A) an induced osteoblast differentiation inducing agent obtained by culturing chondrocytes capable of hypertrophication in a differentiation agent producing medium containing dexamethasone, ?-glycerophosphate, ascorbic acid and a serum component; and B) a biocompatible scaffold. The present invention also provides a method of producing this composite material and a method of promoting or inducing osteogenesis in a biological organism.
    Type: Application
    Filed: June 20, 2008
    Publication date: November 25, 2010
    Applicant: HOYA CORPORATION
    Inventor: Hiroyuki Okihana
  • REPAIR AND TREATMENT OF BONE DEFECT USING CELLS INDUCED BY AGENT PRODUCED BY CHONDROCYTES CAPABLE OF HYPERTROPHICATION AND SCAFFOLD
    Publication number: 20100247601
    Abstract: The present invention provides a method of inducing undifferentiated cells into induced osteoblasts. The method includes: A) a step of providing an induced osteoblast differentiation inducing agent obtained by culturing chondrocytes capable of hypertrophication in a differentiation agent producing medium containing dexamethasone, ?-glycerophosphate, ascorbic acid and a serum component; and B) a step of culturing the undifferentiated cells in an undifferentiated cell culture medium containing the induced osteoblast differentiation inducing agent and a medium component, to differentiate the undifferentiated cells into the induced osteoblasts.
    Type: Application
    Filed: June 20, 2008
    Publication date: September 30, 2010
    Applicant: HOYA CORPORATION
    Inventor: Hiroyuki Okihana
  • Novel cellular function regulating agent produced by a chondrocyte capable of hypertrophication
    Publication number: 20070160976
    Abstract: The present invention provides an agent obtainable by culturing a chondrocyte capable of hypertrophication in a differentiation agent producing medium, wherein the differentiation agent producing medium comprises at least one conventional osteoblast differentiation component selected from the group consisting of glucocorticoid, ?-glycerophosphate and ascorbic acid. The differentiation agent producing medium may comprise all of glucocorticoid, ?-glycerophosphate and ascorbic acid.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 12, 2007
    Applicant: PENTAX Corporation
    Inventor: Hiroyuki Okihana
  • Bone repairing material using a chondrocyte having the potential for hypertrophy and a scaffold
    Publication number: 20060212125
    Abstract: The present invention provides a composite material for enhancing or inducing osteogenesis in a biological organism, comprising A) a chondrocyte having the potential for hypertrophy, and B) a scaffold that is biocompatible with the biological organism. The present invention also provides a method for producing a composite material for enhancing or inducing osteogenesis in a biological organism, comprising A) providing a collected chondrocyte having the potential for hypertrophy, and B) culturing the chondrocyte having the potential for hypertrophy on a scaffold that is biocompatible with the biological organism.
    Type: Application
    Filed: March 17, 2006
    Publication date: September 21, 2006
    Applicant: PENTAX Corporation
    Inventor: Hiroyuki Okihana
  • Method for producing decalcified hard tissue sample
    Publication number: 20060067970
    Abstract: A method for producing a decalcified hard tissue sample by embedding a hard tissue in a liquid-penetration-permitting resin, and then decalcifying it.
    Type: Application
    Filed: September 28, 2005
    Publication date: March 30, 2006
    Applicant: PENTAX Corporation
    Inventors: Hiroyuki Okihana, Masahiro Mukaida