Patents by Inventor Hiroyuki Yokoi

Hiroyuki Yokoi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140127661
    Abstract: Provided is a syringe operation detection device 1 for detecting a drawing or injecting operation of a plunger 120 in a syringe 100. A female joint part 52 is joined to a barrel tip 116 of the syringe 100, a male joint part 60 is joined to a needle hub 132 of a syringe needle 130, and a coupling container 70 is placed between the female joint part 52 and the male joint part 60, for allowing them to be continuous with each other while being closed externally. A detector for detecting a pressure, flow velocity, or flow rate of a fluid moving therein is placed in any one of the coupling container 70, the female joint part 52, and the male joint part 60. As a result, there is provided the syringe operation detection device capable of being applied to a syringe actually used and evaluating a drawing or injecting state in objective terms.
    Type: Application
    Filed: July 20, 2012
    Publication date: May 8, 2014
    Applicant: ICST CORPORATION
    Inventor: Hiroyuki Yokoi
  • Publication number: 20140017712
    Abstract: In a known method of measuring a target substance, comprising: providing a sample solution containing the target substance, a first reaction solution, and a second reaction solution; sequentially aspirating the sample solution and the first reaction solution, using a measuring apparatus equipped with a dispensing unit, into the dispensing unit; discharging them at a time from the dispensing unit, to bring them into contact with the second reaction solution, and to form a complex of the target substance and a first partner which is contained in at least one of the first reaction solution or the second reaction solution and reacts specifically with the target substance; and analyzing the resulting complex, an improved method capable of inhibiting a reaction which adversely affects measurement results is provided.
    Type: Application
    Filed: March 27, 2012
    Publication date: January 16, 2014
    Applicant: Mitsubishi Chemical Medience Corporation
    Inventors: Keiichi Shoji, Hiroyuki Yokoi
  • Patent number: 8557599
    Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: October 15, 2013
    Assignee: Mitsubishi Chemical Medience Corporation
    Inventors: Atsushi Koyata, Hiroyuki Yokoi
  • Publication number: 20130255801
    Abstract: A fluid supply device includes a fluid supply source, a valve, a differential-pressure generator, and a pressurizing device. The valve includes a casing, a displacement member that divides an inside of the casing into a first valve chamber and a second valve chamber, the displacement member being displaced by a pressure of a fluid being exerted on a front main surface and a back main surface of the displacement member, a first opening provided in the first valve chamber, a second opening provided in the first valve chamber, and a third opening provided in the second valve chamber. Thus, flow rate fluctuations are reduced even when the pressure on the ejection side or the suction side of the device fluctuates due to changes in atmospheric conditions.
    Type: Application
    Filed: May 31, 2013
    Publication date: October 3, 2013
    Inventors: Atsuhiko HIRATA, Gaku KAMITANI, Hiroyuki YOKOI
  • Publication number: 20130225939
    Abstract: Provided is a glove for sensitizing touch perception with which fingertips can be moved smoothly across a wide area without influencing subtle touch perception and an examination by means of palpation can be performed highly accurately and smoothly. A glove 1 according to the present invention is a glove for sensitizing touch perception that is for use in detecting minute irregularities of an object via a sensitizing layer 2 by means of a hand inserted between the sensitizing layer 2 and an external cover 3. The sensitizing layer 2 includes: a first film 10 to be in contact with the object; a second film 12 layered on the first film 10; and an air introduction opening 14 for introducing air between the first film 10 and the second film 12 to allow the second film 12 to slide relative to the first film 10.
    Type: Application
    Filed: July 15, 2011
    Publication date: August 29, 2013
    Applicant: ICST CORPORATION
    Inventor: Hiroyuki Yokoi
  • Patent number: 8409872
    Abstract: A cartridge for use in measuring a component to be measured contained in a sample includes a diluting well for diluting a predetermined amount of the sample to a desired dilution, and a reaction well in which the component to be measured contained in the sample and a substance specifically reacting therewith are allowed to react. A diluting solution is filled in the diluting well in a predetermined amount to provide the desired dilution based on a type of the component to be measured when the predetermined amount of the sample is dispensed in the diluting well by a uniform operation.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: April 2, 2013
    Assignee: Mitsubishi Chemical Medience Corporation
    Inventors: Hiroyuki Yokoi, Takashi Kurihara
  • Patent number: 8383421
    Abstract: An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: February 26, 2013
    Assignee: Mitsubishi Chemical Medience Corporation
    Inventors: Atsushi Yanagida, Takashi Kurihara, Hiroyuki Yokoi, Atsushi Koyata, Yoshikazu Okamura, Daishi Miyamoto
  • Publication number: 20130011856
    Abstract: An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Applicant: MITSUBISHI KAGAKU IATRON, INC.
    Inventors: Atsushi YANAGIDA, Takashi KURIHARA, Hiroyuki YOKOI, Atsushi KOYATA, Yoshikazu OKAMURA, Daishi MIYAMOTO
  • Publication number: 20120309025
    Abstract: An analysis method capable of accurately measuring human sCD14-ST when using a whole blood sample is provided. In the analysis method, human sCD14-ST in a whole blood sample is analyzed within 6 hours of the collection of the sample.
    Type: Application
    Filed: January 28, 2011
    Publication date: December 6, 2012
    Applicant: MOCHIDA PHARMACEUTICAL CO., LTD
    Inventors: Yoshikazu Okamura, Hiroyuki Yokoi
  • Publication number: 20120142043
    Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.
    Type: Application
    Filed: December 12, 2011
    Publication date: June 7, 2012
    Applicant: MITSUBISHI CHEMICAL MEDIENCE CORPORATION
    Inventors: Atsushi KOYATA, Hiroyuki YOKOI
  • Patent number: 8053580
    Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: November 8, 2011
    Assignee: Eisal R&D Management Co., Ltd.
    Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga
  • Patent number: 7829718
    Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: November 9, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga
  • Patent number: 7749722
    Abstract: A method for measuring an analyte in a whole blood sample comprising the steps of (1) bringing the whole blood sample into contact with a first substance which is carried on an insoluble carrier and specifically binds to the analyte to be measured and a second substance which is labeled with an alkaline phosphatase and specifically binds to the analyte to be measured, and (2) measuring a resulting complex on the basis of an enzyme reaction of the alkaline phosphatase, the measuring step (2) being carried out in the presence of an inhibitor of endogenous alkaline phosphatases, is disclosed.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: July 6, 2010
    Assignee: Mitsubishi Kagaku Istron, Inc.
    Inventors: Yoshikazu Okamura, Takashi Kurihara, Hiroyuki Yokoi, Junichi Ogawa
  • Patent number: 7740613
    Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: June 22, 2010
    Assignee: Nipro Corporation
    Inventors: Hiroyuki Yokoi, Yukinori Ebara
  • Publication number: 20100049129
    Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.
    Type: Application
    Filed: December 12, 2008
    Publication date: February 25, 2010
    Inventors: Hiroyuki YOKOI, Yukinori Ebara
  • Publication number: 20090264658
    Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
    Type: Application
    Filed: June 24, 2009
    Publication date: October 22, 2009
    Inventors: Hiroyuki YOKOI, Masanori MIZUNO, Toyokazu HAGA
  • Publication number: 20090264659
    Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
    Type: Application
    Filed: June 24, 2009
    Publication date: October 22, 2009
    Inventors: Hiroyuki YOKOI, Masanori MIZUNO, Toyokazu HAGA
  • Publication number: 20090131807
    Abstract: A blood pressure level display device or the like is provided which allows easy measurement and has an improved convenience during measurement. It has a blood pressure display panel 24 having a circumferentially-calibrated scale, and includes: a systolic blood pressure indicating unit for providing a systolic blood pressure indication based on a state of systolic blood pressure; and a diastolic blood pressure indicating unit for providing a diastolic blood pressure indication based on a state of diastolic blood pressure.
    Type: Application
    Filed: July 21, 2006
    Publication date: May 21, 2009
    Inventor: Hiroyuki Yokoi
  • Publication number: 20080096285
    Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.
    Type: Application
    Filed: July 27, 2005
    Publication date: April 24, 2008
    Inventors: Atsushi Koyata, Hiroyuki Yokoi
  • Publication number: 20080090877
    Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
    Type: Application
    Filed: August 5, 2005
    Publication date: April 17, 2008
    Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga