Patents by Inventor Hiroyuki Yokoi
Hiroyuki Yokoi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140127661Abstract: Provided is a syringe operation detection device 1 for detecting a drawing or injecting operation of a plunger 120 in a syringe 100. A female joint part 52 is joined to a barrel tip 116 of the syringe 100, a male joint part 60 is joined to a needle hub 132 of a syringe needle 130, and a coupling container 70 is placed between the female joint part 52 and the male joint part 60, for allowing them to be continuous with each other while being closed externally. A detector for detecting a pressure, flow velocity, or flow rate of a fluid moving therein is placed in any one of the coupling container 70, the female joint part 52, and the male joint part 60. As a result, there is provided the syringe operation detection device capable of being applied to a syringe actually used and evaluating a drawing or injecting state in objective terms.Type: ApplicationFiled: July 20, 2012Publication date: May 8, 2014Applicant: ICST CORPORATIONInventor: Hiroyuki Yokoi
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Publication number: 20140017712Abstract: In a known method of measuring a target substance, comprising: providing a sample solution containing the target substance, a first reaction solution, and a second reaction solution; sequentially aspirating the sample solution and the first reaction solution, using a measuring apparatus equipped with a dispensing unit, into the dispensing unit; discharging them at a time from the dispensing unit, to bring them into contact with the second reaction solution, and to form a complex of the target substance and a first partner which is contained in at least one of the first reaction solution or the second reaction solution and reacts specifically with the target substance; and analyzing the resulting complex, an improved method capable of inhibiting a reaction which adversely affects measurement results is provided.Type: ApplicationFiled: March 27, 2012Publication date: January 16, 2014Applicant: Mitsubishi Chemical Medience CorporationInventors: Keiichi Shoji, Hiroyuki Yokoi
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Patent number: 8557599Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.Type: GrantFiled: December 12, 2011Date of Patent: October 15, 2013Assignee: Mitsubishi Chemical Medience CorporationInventors: Atsushi Koyata, Hiroyuki Yokoi
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Publication number: 20130255801Abstract: A fluid supply device includes a fluid supply source, a valve, a differential-pressure generator, and a pressurizing device. The valve includes a casing, a displacement member that divides an inside of the casing into a first valve chamber and a second valve chamber, the displacement member being displaced by a pressure of a fluid being exerted on a front main surface and a back main surface of the displacement member, a first opening provided in the first valve chamber, a second opening provided in the first valve chamber, and a third opening provided in the second valve chamber. Thus, flow rate fluctuations are reduced even when the pressure on the ejection side or the suction side of the device fluctuates due to changes in atmospheric conditions.Type: ApplicationFiled: May 31, 2013Publication date: October 3, 2013Inventors: Atsuhiko HIRATA, Gaku KAMITANI, Hiroyuki YOKOI
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Publication number: 20130225939Abstract: Provided is a glove for sensitizing touch perception with which fingertips can be moved smoothly across a wide area without influencing subtle touch perception and an examination by means of palpation can be performed highly accurately and smoothly. A glove 1 according to the present invention is a glove for sensitizing touch perception that is for use in detecting minute irregularities of an object via a sensitizing layer 2 by means of a hand inserted between the sensitizing layer 2 and an external cover 3. The sensitizing layer 2 includes: a first film 10 to be in contact with the object; a second film 12 layered on the first film 10; and an air introduction opening 14 for introducing air between the first film 10 and the second film 12 to allow the second film 12 to slide relative to the first film 10.Type: ApplicationFiled: July 15, 2011Publication date: August 29, 2013Applicant: ICST CORPORATIONInventor: Hiroyuki Yokoi
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Patent number: 8409872Abstract: A cartridge for use in measuring a component to be measured contained in a sample includes a diluting well for diluting a predetermined amount of the sample to a desired dilution, and a reaction well in which the component to be measured contained in the sample and a substance specifically reacting therewith are allowed to react. A diluting solution is filled in the diluting well in a predetermined amount to provide the desired dilution based on a type of the component to be measured when the predetermined amount of the sample is dispensed in the diluting well by a uniform operation.Type: GrantFiled: October 28, 2002Date of Patent: April 2, 2013Assignee: Mitsubishi Chemical Medience CorporationInventors: Hiroyuki Yokoi, Takashi Kurihara
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Patent number: 8383421Abstract: An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.Type: GrantFiled: January 17, 2006Date of Patent: February 26, 2013Assignee: Mitsubishi Chemical Medience CorporationInventors: Atsushi Yanagida, Takashi Kurihara, Hiroyuki Yokoi, Atsushi Koyata, Yoshikazu Okamura, Daishi Miyamoto
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Publication number: 20130011856Abstract: An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.Type: ApplicationFiled: September 14, 2012Publication date: January 10, 2013Applicant: MITSUBISHI KAGAKU IATRON, INC.Inventors: Atsushi YANAGIDA, Takashi KURIHARA, Hiroyuki YOKOI, Atsushi KOYATA, Yoshikazu OKAMURA, Daishi MIYAMOTO
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Publication number: 20120309025Abstract: An analysis method capable of accurately measuring human sCD14-ST when using a whole blood sample is provided. In the analysis method, human sCD14-ST in a whole blood sample is analyzed within 6 hours of the collection of the sample.Type: ApplicationFiled: January 28, 2011Publication date: December 6, 2012Applicant: MOCHIDA PHARMACEUTICAL CO., LTDInventors: Yoshikazu Okamura, Hiroyuki Yokoi
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Publication number: 20120142043Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.Type: ApplicationFiled: December 12, 2011Publication date: June 7, 2012Applicant: MITSUBISHI CHEMICAL MEDIENCE CORPORATIONInventors: Atsushi KOYATA, Hiroyuki YOKOI
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Patent number: 8053580Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).Type: GrantFiled: June 24, 2009Date of Patent: November 8, 2011Assignee: Eisal R&D Management Co., Ltd.Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga
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Patent number: 7829718Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).Type: GrantFiled: August 5, 2005Date of Patent: November 9, 2010Assignee: Eisai R&D Management Co., Ltd.Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga
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Patent number: 7749722Abstract: A method for measuring an analyte in a whole blood sample comprising the steps of (1) bringing the whole blood sample into contact with a first substance which is carried on an insoluble carrier and specifically binds to the analyte to be measured and a second substance which is labeled with an alkaline phosphatase and specifically binds to the analyte to be measured, and (2) measuring a resulting complex on the basis of an enzyme reaction of the alkaline phosphatase, the measuring step (2) being carried out in the presence of an inhibitor of endogenous alkaline phosphatases, is disclosed.Type: GrantFiled: December 15, 2005Date of Patent: July 6, 2010Assignee: Mitsubishi Kagaku Istron, Inc.Inventors: Yoshikazu Okamura, Takashi Kurihara, Hiroyuki Yokoi, Junichi Ogawa
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Patent number: 7740613Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.Type: GrantFiled: December 12, 2008Date of Patent: June 22, 2010Assignee: Nipro CorporationInventors: Hiroyuki Yokoi, Yukinori Ebara
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Publication number: 20100049129Abstract: An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.Type: ApplicationFiled: December 12, 2008Publication date: February 25, 2010Inventors: Hiroyuki YOKOI, Yukinori Ebara
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Publication number: 20090264658Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).Type: ApplicationFiled: June 24, 2009Publication date: October 22, 2009Inventors: Hiroyuki YOKOI, Masanori MIZUNO, Toyokazu HAGA
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Publication number: 20090264659Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).Type: ApplicationFiled: June 24, 2009Publication date: October 22, 2009Inventors: Hiroyuki YOKOI, Masanori MIZUNO, Toyokazu HAGA
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Publication number: 20090131807Abstract: A blood pressure level display device or the like is provided which allows easy measurement and has an improved convenience during measurement. It has a blood pressure display panel 24 having a circumferentially-calibrated scale, and includes: a systolic blood pressure indicating unit for providing a systolic blood pressure indication based on a state of systolic blood pressure; and a diastolic blood pressure indicating unit for providing a diastolic blood pressure indication based on a state of diastolic blood pressure.Type: ApplicationFiled: July 21, 2006Publication date: May 21, 2009Inventor: Hiroyuki Yokoi
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Publication number: 20080096285Abstract: A method of determining a kind of a sample, in a method for analyzing a substance by the steps of supplying the sample to be analyzed to a reaction system by a supplying means comprising a transparent region composed of a transparent material, reacting a reagent for detecting the substance with the sample in the reaction system, and analyzing a signal derived from a product obtained by the reaction, characterized by irradiating the transparent region with light in the supplying step, and analyzing an optical intensity of the light.Type: ApplicationFiled: July 27, 2005Publication date: April 24, 2008Inventors: Atsushi Koyata, Hiroyuki Yokoi
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Publication number: 20080090877Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).Type: ApplicationFiled: August 5, 2005Publication date: April 17, 2008Inventors: Hiroyuki Yokoi, Masanori Mizuno, Toyokazu Haga