Patents by Inventor Hisaaki Ishiguro

Hisaaki Ishiguro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activation of endothelial nitric oxide synthase by midkine and uses therefor in effecting vasodilation
    Patent number: 8288343
    Abstract: The object is to find a nitric oxide synthase activator, a method for the administration of the activator, and the amount of the activator to be administered. Disclosed is a nitric oxide synthase activator comprising a midkine family protein or a midkine derivative as an active ingredient. Specifically disclosed is a nitric oxide synthase activator which is intended to be administered through the blood, a coronary artery or a vein and which comprises a midkine family protein or a midkine derivative as an active ingredient.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: October 16, 2012
    Assignee: National University Corporation Nagoya University
    Inventors: Mitsuru Horiba, Kenji Kadomatsu, Itsuo Kodama, Takashi Muramatsu, Hisaaki Ishiguro, Hiroharu Takenaka, Arihiro Sumida
  • NITRIC OXIDE SYNTHASE ACTIVATOR
    Publication number: 20100197577
    Abstract: The object is to find a nitric oxide synthase activator, a method for the administration of the activator, and the amount of the activator to be administered. Disclosed is a nitric oxide synthase activator comprising a midkine family protein or a midkine derivative as an active ingredient. Specifically disclosed is a nitric oxide synthase activator which is intended to be administered through the blood, a coronary artery or a vein and which comprises a midkine family protein or a midkine derivative as an active ingredient.
    Type: Application
    Filed: March 28, 2008
    Publication date: August 5, 2010
    Inventors: Mitsuru Horiba, Kenji Kadomatsu, Itsuo Kodama, Takashi Muramatsu, Hisaaki Ishiguro, Hiroharu Takenaka, Arihiro Sumida