Patents by Inventor Hisakage Funabashi

Hisakage Funabashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INSULIN DETECTION METHOD AND INSULIN DETECTION KIT
    Publication number: 20230068436
    Abstract: An insulin detection method includes: adding a sample to an electrode having an insulin binding protein immobilized on a surface of the electrode, the insulin binding protein specifically recognizing insulin; and detecting an electrochemical change associated with formation of a complex of the insulin and the insulin binding protein. The insulin binding protein includes: a first region that includes an ?-CT segment of an insulin receptor and does not include a ? subunit of the insulin receptor, and a second region that includes an L1 domain of the insulin receptor and does not include the ? subunit of the insulin receptor; and one of the first region and the second region is immobilized on the surface of the electrode.
    Type: Application
    Filed: October 14, 2022
    Publication date: March 2, 2023
    Applicants: HIROSHIMA UNIVERSITY, TERUMO KABUSHIKI KAISHA
    Inventors: Hisakage FUNABASHI, Akio KURODA, Hiroya SATO
  • Purification method, purification kit, and silicon oxide-binding tag for use therein
    Patent number: 10253064
    Abstract: The present invention provides a method for purifying an intended substance, a kit for purifying the intended substance, and a silicon oxide-binding tag for use in the method and the kit. In the present invention, a complex of a silicon oxide-binding tag and a substance is caused to specifically bind to silicon oxide in a solution for binding, to which solution no salt is added, and binding between the silicon oxide-binding tag and the silicon oxide is broken with use of arginine.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: April 9, 2019
    Assignee: Hiroshima University
    Inventors: Akio Kuroda, Takeshi Ikeda, Hisakage Funabashi
  • PURIFICATION METHOD, PURIFICATION KIT, AND SILICON OXIDE-BINDING TAG FOR USE THEREIN
    Publication number: 20180327448
    Abstract: The present invention provides a method for purifying an intended substance, a kit for purifying the intended substance, and a silicon oxide-binding tag for use in the method and the kit. In the present invention, a complex of a silicon oxide-binding tag and a substance is caused to specifically bind to silicon oxide in a solution for binding, to which solution no salt is added, and binding between the silicon oxide-binding tag and the silicon oxide is broken with use of arginine.
    Type: Application
    Filed: October 21, 2015
    Publication date: November 15, 2018
    Applicant: Hiroshima University
    Inventors: Akio KURODA, Takeshi IKEDA, Hisakage FUNABASHI
  • Nucleic acid hydrogel via rolling circle amplification
    Patent number: 8715732
    Abstract: Methods and compositions are provided for producing nucleic acid-based compositions. Methods include enzyme catalyzed or nucleic acid polymer conjugation. Compositions include nucleic acid-containing hydrogels which can be elongated via rolling circle amplification. The hydrogels can encapsulate bioactive agents for drug delivery.
    Type: Grant
    Filed: January 5, 2010
    Date of Patent: May 6, 2014
    Assignee: Cornell University
    Inventors: Dan Luo, Jong Bum Lee, Hisakage Funabashi
  • NUCLEIC ACID HYDROGEL VIA ROLLING CIRCLE AMPLIFICATION
    Publication number: 20100189794
    Abstract: Methods and compositions are provided for producing nucleic acid-based compositions. Methods include enzyme catalyzed or nucleic acid polymer conjugation. Compositions include nucleic acid-containing hydrogels which can be elongated via rolling circle amplification. The hydrogels can encapsulate bioactive agents for drug delivery.
    Type: Application
    Filed: January 5, 2010
    Publication date: July 29, 2010
    Applicant: Cornell University
    Inventors: Dan Luo, Jong Bum Lee, Hisakage Funabashi