Abstract: Chronic pain patients complain about sleep disturbance with a high probability, while sleep loss increases pain in chronic pain patients. Sleep problems and pain promote a vicious spiral, suggesting a need for simultaneous treatment of both. The present invention provides a method to treat pain-related sleep disorders through distribution of a therapeutic amount of a KOR antagonist. The use of KOR antagonist could be a novel therapeutic agent for sleep disturbance in chronic pain patients. Additionally, KOR antagonists could be used to improve sleep in other conditions, such as depression or general anxiety disorder, where KOR signaling is induced.

Abstract: A three-dimensional image display apparatus of the invention can be easily operated by the operator while a three-dimensional image created by the apparatus is observed by him. A depth information maximum value acquisition circuit acquires depth information contained in a first image signal. A parallax control circuit controls the parallax amount of a second image signal on the basis of depth information contained in the first and second image signals such that an image corresponding to the second image signal can be three-dimensionally displayed in front of an image corresponding to the first image signal. A three-dimensional image synthesizer synthesizes the first and second image signals which has been controlled by the parallax control circuit, on the basis of the parallax amount of each image signal, such that images correspond to that the first and second image signals in the three-dimensional display space.

Abstract: A video signal processor for preventing image damage resulting from when a first signal and a second signal are converted into each other. When a first signal (an interlaced scanning format signal) is inputted, according to a mode discriminating signal from a mode discriminator, a mixer/selector receives the motion detecting signal from the mode discriminator, adaptively mixes both outputs of a delay circuit and a line interpolating filter (IPF) and uses the combined outputs as an interpolation signal. When a second signal (a progressive scanning format signal converted to an interlaced scanning format signal) is inputted, the mixer/selector selects either the output of the second signal or the output of a delay circuit according to the mode discriminating signal and the field indexes from the mode discriminator and makes it as an interpolation signal.

Abstract: A novel 2-imino derivative of an antifungal product KA-7367A represented by formula, ##STR1## which has high antifungal activity and excellent stability and is useful as an antifungal agent for warm-blooded animals including humans and for agricultural and horticultural usages.

Abstract: Novel azoxy compounds having antifungal activity and being useful for the treatment of mycoses, represented by the following formula ##STR1## are prepared by culturing a microorganism of Streptomyces sp. (KC-7367, FERM BP-1277) and separating the compounds from the culture broth.

Abstract: A novel antibiotic designated as KA-6643 and having the formula, ##STR1## wherein R is hydrogen or --SO.sub.3 H.

Abstract: A-KA-6643-series antibiotic comprising at least one substance represented by any of the following formulae, or a salt or ester thereof: ##STR1## is effectively useful as an antibacterial and .beta.-lactamase inhibiting agent.

Abstract: Novel antibiotics of the following structure ##STR1## wherein R represents a moiety selected from the group consisting of hydrogen, --COCH.sub.2 NH.sub.2, --COCH.sub.2 NHCONH.sub.2 and --COCH.sub.2 NHCHO;process for preparation thereof; and biologically pure culture for use therein.

Abstract: Novel antibiotics of the following structure ##STR1## wherein R represents a moiety selected from the group consisting of hydrogen, --COCH.sub.2 NH.sub.2, --COCH.sub.2 NHCONH.sub.2 and --COCH.sub.2 NHCHO; process for preparation thereof; and biologically pure culture for use therein.

Abstract: Novel antibiotics of the following structure ##STR1## wherein R represents a moiety selected from the group consisting of hydrogen, --COCH.sub.2 NH.sub.2, --COCH.sub.2 NHCONH.sub.2 and --COCH.sub.2 NHCHO;process for preparation thereof; and biologically pure culture for use therein.