Patents by Inventor Hisakazu Hasegawa

Hisakazu Hasegawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8937218
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: January 20, 2015
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Mikio Shoji, Takeshi Kawarabayashi, Yasuko Utsumi
  • Patent number: 8912145
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: December 16, 2014
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • Publication number: 20120052086
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 1, 2012
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • Publication number: 20110243975
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Application
    Filed: November 26, 2009
    Publication date: October 6, 2011
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Shigeru Utsumi, Yasuko Utsumi, Mikio Shoji, Takeshi Kawarabayashi
  • Patent number: 7795505
    Abstract: A DNA encoding a phosphinothricin acetyltransferase protein obtained from Streptomyces sp. AB3534 strain is described which imparts a resistance to herbicides, particularly the herbicide phosphinothricin (PPT). Plants having a herbicide resistance are constructed by transforming a plant cell with DNA encoding the phosphinothricin acetyltransferase protein and then regenerating the transformed plant cell into a plant. A recombinant protein having the herbicide-resistant activity is also described.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: September 14, 2010
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Hisakazu Hasegawa, Teruhiko Terakawa, Kiyoshi Hirazawa
  • Publication number: 20090158469
    Abstract: To provide a novel herbicide-resistance gene and a plant imparted a resistance to herbicides by using this gene, a plant having a resistance to herbicides is constructed by transforming a plant cell by a DNA encoding the following protein (A) or (B) and then regenerating the thus transformed plant cell in a plant. (A) A protein having the amino acid sequence represented by SEQ ID NO:2. (B) A protein having an amino acid sequence of SEQ ID NO:2 including substitution, deletion, insertion or addition of one or plural amino acids and having a herbicide-resistant activity.
    Type: Application
    Filed: November 8, 2005
    Publication date: June 18, 2009
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Hisakazu Hasegawa, Teruhiko Terakawa, Kiyoshi Hirazawa
  • Publication number: 20090100552
    Abstract: A plant having improved heat tolerance and/or increased growth is produced by steps of: introducing DNA into a plant cell to produce a transformed plant cell, wherein the DNA is selected from the group consisting of: (a) DNA coding for a protein consisting of the amino acid sequence represented by SEQ ID NO: 2, (b) DNA including the coding region of the nucleotide sequence represented by SEQ ID NO: 1, (c) DNA coding for a protein having an amino acid sequence represented by SEQ ID NO: 2 in which one or a few amino acids are substituted, deleted, inserted, and/or added, and being involved in growth promoting effect and heat tolerance, (d) DNA hybridizing with DNA consisting of the nucleotide sequence represented by SEQ ID NO: 1 under stringent conditions and coding for a protein which is involved in growth promoting effect and heat tolerance, and (e) DNA coding for a protein having an amino acid sequence having 90% or more identity with the amino acid sequence represented by SEQ ID NO: 2 and being involved in
    Type: Application
    Filed: January 16, 2007
    Publication date: April 16, 2009
    Inventors: Tomokazu Koshiba, Teruhiko Terakawa, Hisakazu Hasegawa, Setsuko Komatsu, Takashi Okamoto, Toshiko Furukawa, Kentaroh Shimaya
  • Patent number: 6451537
    Abstract: In accordance with this invention, there is provided a DNA sequence which can encode an enzyme protein functioning as the rice dihydrodipicolinate synthase (DHDPS). One example of the DNA sequence according to this invention is the DNA having the nucleotide sequence shown in SEQ ID No. 1 of Sequence Listing. Additionally, this invention provides the DNA having the nucleotide sequence of SEQ ID No. 5, as well as the DNA having the nucleotide sequence of SEQ ID No. 7 of Sequence Listing, as the DNA which is capable of encoding the protein having the DHDPS activity. When cultivation is made of the plant cells in which there has been introduced a recombinant vector having carried therein a DNA fragment containing the DNA of this invention as inserted at downstream of the promoter of said recombinant vector, it is feasible to regenerate from said plant cells a transgenic plant having a high lysine content.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: September 17, 2002
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masanori Yamaguchi
  • Patent number: 6388174
    Abstract: A DNA sequence is provided, which encodes an enzyme that is the &agr;-subunit of the first isozyme of rice anthranilate synthase (ASA). Transformed plants having a high tryptophan content can be regenerated by culturing the plant cells having introduced therein such a recombinant vector which contains, at a position downstream of a promoter, an inserted DNA fragment carrying the above DNA sequence. In addition, methods of selecting transformed plant cells are disclosed, wherein plant cells transformed with the discloses DNA are resistant to inhibitory concentrations of tryptophan or tryptophan analogues.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: May 14, 2002
    Assignees: Hokko Chemical Industry Co., Ltd., National Agricultural Research Organization (NARO)
    Inventors: Kyo Wakasa, Yuzuru Tozawa, Teruhiko Terakawa, Hisakazu Hasegawa