Patents by Inventor Hisaki Nagai

Hisaki Nagai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9353416
    Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: May 31, 2016
    Assignees: Mitsubishi Rayon Co., Ltd., Nippon Medical School
    Inventors: Mitsuru Emi, Masamitsu Onda, Hisaki Nagai
  • Publication number: 20130203621
    Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.
    Type: Application
    Filed: January 9, 2013
    Publication date: August 8, 2013
    Inventors: Mitsuru Emi, Masamitsu Onda, Hisaki Nagai
  • Publication number: 20110009284
    Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.
    Type: Application
    Filed: May 21, 2010
    Publication date: January 13, 2011
    Applicants: MITSUBISHI RAYON CO., LTD., NIPPON MEDICAL SCHOOL
    Inventors: Mitsuru EMI, Masamitsu ONDA, Hisaki NAGAI
  • Publication number: 20080026950
    Abstract: It is intended to provide a system of predicting the postoperative prognosis in a patient with breast cancer from the viewpoint of gene expression based on the data obtained by genome-wide and comprehensive analysis on gene expression in breast cancer. Expression of human genes is comprehensively analyzed by using a DNA microarray and gene expression functions in various breast cancer conditions are compared, thereby establishing a system of predicting the postoperative prognosis of breast cancer.
    Type: Application
    Filed: August 24, 2004
    Publication date: January 31, 2008
    Applicant: Mitsubishi Rayon Co., Ltd.
    Inventors: Mitsuru Emi, Masamitsu Onda, Hisaki Nagai
  • Publication number: 20040076950
    Abstract: Compositions for the diagnosis of hepatocellular carcinoma (HCC), tumor suppressor genes associated with HCC, methods for diagnosing various forms of HCC, methods for detecting genetic abnormalities associated with HCC, as well as kits for carrying out the methods, are disclosed.
    Type: Application
    Filed: March 28, 2001
    Publication date: April 22, 2004
    Applicants: Institut Pasteur, Institut Nationale de la Sante et de la Recherche Medicale
    Inventors: Anne Dejean, Marie Annick Buendia, Pascal Pineau, Hisaki Nagai
  • Patent number: 6410724
    Abstract: The present invention pertains to new polynucleotides or new combinations of polynucleotides useful as diagnostic tools for predicting the occurrence of a human hepatocellular carcinoma disease. The invention is also directed to polynucleotides that consist in candidate tumor suppressor genes the alteration of which is involved in the occurrence of hepatocellular carcinoma in a patient, as well as to polynucleotides derived from such new candidate tumor suppressor genes and to the corresponding expressed polypeptides. The invention also concerns diagnostic methods using said polynucleotides as diagnostic tools.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: June 25, 2002
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Anne Dejean, Marie-Annick Buendia, Pascal Pineau, Hisaki Nagai, Pierre Tiollais
  • Publication number: 20020042073
    Abstract: The present invention pertains to new polynucleotides or new combinations of polynucleotides useful as diagnostic tools for predicting the occurrence of a human hepatocellular carcinoma disease. The invention is also directed to polynucleotides that consist in candidate tumor suppressor genes the alteration of which is involved in the occurrence of hepatocellular carcinoma in a patient, as well as to polynucleotides derived from such new candidate tumor suppressor genes and to the corresponding expressed polypeptides. The invention also concerns diagnostic methods using said polynucleotides as diagnostic tools.
    Type: Application
    Filed: July 6, 2001
    Publication date: April 11, 2002
    Applicant: INSTITUT PASTEUR
    Inventors: Anne Dejean, Marie-Annick Buendia, Pascal Pineau, Hisaki Nagai, Pierre Tiollais
  • Patent number: 6265161
    Abstract: A method for detecting a predisposition to hepatocellular carcinoma (HCC) using a unique panel of primers for identifying genetic alterations that are linked to HCC, as well as kits for carrying out the methods, are disclosed.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: July 24, 2001
    Assignee: Institut Pasteur and Institut Nationale de la Sante et de la Recherche Medicale
    Inventors: Anne Dejean, Marie Annick Buendia, Pascal Pineau, Hisaki Nagai