Patents by Inventor Hisanori Nasu

Hisanori Nasu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5290419
    Abstract: In the multi-color fluorescence detection type electrophoresis apparatus provided with the electrophoresis gel plate, excitation laser source, means to separate the fluorescence images according to each emission wavelength, and the detector of the fluorescence subjected to wavelength selection, two or more laser sources are provided, each of laser lights is irradiated on the sample on a time-sharing basis, and the filter which cuts off the scattered light of each the laser synchronous with the laser beam is installed in front of the wavelength separation means thereby providing simultaneous, quick and real-time analysis of a great number of samples such as DNA and RNA labeled by many types of fluorophores, without overlapping the wavelengths of the excitation light and the fluorescence.
    Type: Grant
    Filed: April 12, 1993
    Date of Patent: March 1, 1994
    Assignees: Hitachi, Ltd., Hitachi Electronics Engineering Co., Ltd., Hitachi Software Engineering Co.
    Inventors: Hideki Kambara, Takashi Anazawa, Keiichi Nagai, Hiroaki Machida, Hisanori Nasu
  • Patent number: 5246866
    Abstract: A DNA sequence transcribing method involves labeling a DNA fragment with a fluorescent substance, subjecting the labeled fragments to electrophoresis, exposing a gel containing the DNA fragment to light during electrophoresis, and detecting fluorescence generated upon exposure. An image corresponding to a fluorescent image on the gel is transcribed on a recording medium by entering a detecting signal in synchronization with operation of detecting fluorescence on the gel containing the DNA fragment after electrophoresis. This arrangement enables a crude fluorescent image on the gel containing the DNA fragment to be recorded as an intact image of the DNA sequencing on the basis of the fluorescent method, and the image can be retained.
    Type: Grant
    Filed: March 2, 1992
    Date of Patent: September 21, 1993
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hisanori Nasu, Toshitsugu Okayama, Hitoshi Fujimiya
  • Patent number: 5242567
    Abstract: A fluorescence pattern reading apparatus for reading a fluorescence pattern by exciting a fluorescence substance labeled on a sample developed into an electrophoresis pattern by electrophoresis of the sample has optical scanning mechanisms, a light-receiving unit, a photoelectric converting unit, and amplifiers. The mechanisms are to irradiate the gel in the direction of thickness of the gel by scanning the irradiation light for exciting the fluorescent substance of the fluorescence patter. The light-receiving unit is to receive the fluorescence by separating the fluorescence from the light scattered on the reading surface of the gel due to a spatial position relationship of a light-receiving path in which the light-receiving surface is set to exist in the direction different from the axis of the irradiation light. The photoelectric converting unit is to generate electric signals by converting light signals received by the light-receiving unit.
    Type: Grant
    Filed: May 22, 1991
    Date of Patent: September 7, 1993
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hitoshi Fujimiya, Hiromichi Mishima, Toshitaka Ishikawa, Kouji Yuda, Hisanori Nasu
  • Patent number: 5213673
    Abstract: A multi-colored electrophoresis pattern reading apparatus is capable of labelling each of plural samples separately with each of plural fluorescent substances having different fluorescence wavelengths, by electrophoresing the plural samples to develop a pattern, exciting the fluorescent substances labelled on the samples to emit fluorescence, and reading a fluorescent pattern emitting the fluorescence.
    Type: Grant
    Filed: November 29, 1991
    Date of Patent: May 25, 1993
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hitoshi Fujimiya, Hisanori Nasu
  • Patent number: 5190632
    Abstract: The multi-colored electrophoresis pattern reading system compares the patterns of electrophoresis without a warp to be caused upon electrophoresis by reading the patterns of electrophoresis which is carried out concurrently for plural samples and by labelling the samples with fluorescent substances having different fluorescent wavelengths. The patterns of electrophoresis are read by allowing fluorescence to emit from the plural samples. In reading the fluorescent patterns, optical signals are received by the light receiving section and then the fluorescence having a predetermined wavelength is separated by the fluorescent-wavelength separating section from the optical signals with the aid of an optical filter capable of controlling an angle of incidence relative to the optical axis of the optical filter.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: March 2, 1993
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hitoshi Fujimiya, Hisanori Nasu
  • Patent number: 5069769
    Abstract: An electrophoresis pattern reading system of fluorescent type is comprised of a detachable migration unit comprising a gel functioning as a base for electrophoresis and a gel-supporting body for supporting the gel; an electrophoresis unit, to which the migration unit is mounted, for performing electrophoresis by applying migrating voltage to the gel to which a sample labeled with a fluorescent substance is added; and a reading unit including an instrumentation subunit for reading an electrophoresis pattern, to which the migration unit is mounted after electrophoresis and which receives fluorescence emitted from the fluorescent substance of the sample on the gel upon application of light to the gel.
    Type: Grant
    Filed: June 6, 1990
    Date of Patent: December 3, 1991
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hitoshi Fujimiya, Shigeo Nakajima, Hisanori Nasu
  • Patent number: 4706192
    Abstract: An input apparatus for entering base sequence information of the gene, comprises a computer for analyzing the base sequence of the gene, an input apparatus for entering base sequence information of the gene to the computer which successively stores the base sequence information entered by the input apparatus and produces the stored base sequence information, and a speech sounding apparatus supplied with the base sequence information produced from the computer for sounding speech corresponding to the base sequence information produced from the computer.
    Type: Grant
    Filed: April 26, 1985
    Date of Patent: November 10, 1987
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Hisanori Nasu, Satoru Suzuki, Hiroaki Yoshida, Tomoichi Fukuda, Eiichi Soeda